MGE detailed information
MGE type: Conjugative plasmid MGE length: 101966 bp
Accession: NZ_AP022535 Location: 1..101966 Organism: Escherichia coli strain THO-006 Replicon: plasmid pTHO-006-2
Accession: NZ_AP022535 Location: 1..101966 Organism: Escherichia coli strain THO-006 Replicon: plasmid pTHO-006-2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JLF32_RS24920 () | 102..1079 | + | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| JLF32_RS24925 () | 1364..2104 | - | 741 | WP_001066941.1 | tyrosine-type recombinase/integrase | - |
| JLF32_RS24930 () | 2225..2413 | - | 189 | WP_001309252.1 | hypothetical protein | - |
| JLF32_RS24935 () | 2780..3949 | + | 1170 | WP_001072358.1 | hypothetical protein | - |
| JLF32_RS24940 () | 4175..4350 | - | 176 | Protein_4 | IS3 family transposase | - |
| JLF32_RS24945 () | 4796..5068 | - | 273 | WP_001322642.1 | Major pilu subunit operon regulatory protein PapB | VF |
| JLF32_RS24950 () | 5593..6029 | - | 437 | Protein_6 | IS3 family transposase IS2 | Transposase |
| JLF32_RS24955 () | 6311..7678 | + | 1368 | Protein_7 | Hemin receptor | VF |
| JLF32_RS24960 () | 7732..8436 | - | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| JLF32_RS24965 () | 8499..8750 | + | 252 | Protein_9 | IS1 family transposase IS1R | Transposase |
| JLF32_RS24970 () | 8887..9819 | - | 933 | WP_000991832.1 | hypothetical protein | - |
| JLF32_RS24975 () | 9823..10818 | - | 996 | WP_000246636.1 | hypothetical protein | - |
| JLF32_RS24980 () | 11526..11744 | + | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| JLF32_RS24985 () | 11746..12051 | + | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| JLF32_RS24990 () | 12052..12858 | + | 807 | WP_000016982.1 | site-specific integrase | - |
| JLF32_RS24995 () | 13632..14387 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| JLF32_RS25000 () | 14975..16141 | + | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| JLF32_RS25005 () | 16141..17112 | + | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| JLF32_RS25010 () | 17979..18881 | + | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| JLF32_RS25015 () | 18885..19189 | + | 305 | Protein_19 | hypothetical protein | - |
| JLF32_RS25020 () | 19266..19949 | + | 684 | WP_000086185.1 | DNA methylase | - |
| JLF32_RS25025 () | 19950..20171 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| JLF32_RS25030 () | 20185..20619 | + | 435 | WP_000274437.1 | DUF1380 family protein | - |
| JLF32_RS25035 () | 20670..21446 | + | 777 | WP_001753849.1 | hypothetical protein | - |
| JLF32_RS25040 () | 21986..22288 | + | 303 | WP_001671341.1 | antirestriction protein | - |
| JLF32_RS25045 () | 22335..22757 | + | 423 | WP_000271753.1 | DUF1380 family protein | - |
| JLF32_RS25050 () | 22754..22945 | + | 192 | WP_001027516.1 | hypothetical protein | - |
| JLF32_RS25055 () | 23980..24210 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| JLF32_RS25060 () | 24262..25623 | + | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| JLF32_RS25065 () | 25671..26234 | + | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| JLF32_RS25070 () | 26260..26508 | + | 249 | WP_001553845.1 | hypothetical protein | - |
| JLF32_RS25075 () | 26671..27006 | + | 336 | WP_013023883.1 | hypothetical protein | - |
| JLF32_RS25080 () | 27151..27690 | + | 540 | WP_000290841.1 | single-stranded DNA-binding protein | - |
| JLF32_RS25085 () | 27753..27986 | + | 234 | WP_000005990.1 | DUF905 family protein | - |
| JLF32_RS25090 () | 28052..30010 | + | 1959 | WP_000117179.1 | ParB/RepB/Spo0J family partition protein | - |
| JLF32_RS25095 () | 30065..30499 | + | 435 | WP_000845940.1 | conjugation system SOS inhibitor PsiB | - |
| JLF32_RS25100 () | 30496..31215 | + | 720 | WP_001276232.1 | plasmid SOS inhibition protein A | - |
| - () | 31227..31413 | + | 187 | NuclAT_0 | - | - |
| - () | 31227..31413 | + | 187 | NuclAT_0 | - | - |
| - () | 31227..31413 | + | 187 | NuclAT_0 | - | - |
| - () | 31227..31413 | + | 187 | NuclAT_0 | - | - |
| JLF32_RS25105 () | 31461..32830 | + | 1370 | WP_085947770.1 | IS3 family transposase IS150 | Transposase |
| - () | 32857..32897 | + | 41 | NuclAT_1 | - | Antitoxin Detail |
| - () | 32857..32897 | + | 41 | NuclAT_1 | - | Antitoxin Detail |
| - () | 32857..32897 | + | 41 | NuclAT_1 | - | Antitoxin Detail |
| - () | 32857..32897 | + | 41 | NuclAT_1 | - | Antitoxin Detail |
| JLF32_RS25110 () | 32941..33099 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| JLF32_RS25115 () | 33542..33877 | + | 336 | WP_013023876.1 | hypothetical protein | - |
| JLF32_RS25120 () | 33790..33996 | + | 207 | WP_000275859.1 | hypothetical protein | - |
| JLF32_RS25125 () | 34021..34308 | + | 288 | WP_000107535.1 | hypothetical protein | - |
| JLF32_RS25130 () | 34427..35248 | + | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| JLF32_RS25135 () | 35545..36147 | - | 603 | WP_000243712.1 | hypothetical protein | VF |
| JLF32_RS25140 () | 36478..36861 | + | 384 | WP_001151566.1 | relaxosome protein TraM | - |
| JLF32_RS25145 () | 36994..37671 | + | 678 | WP_001348626.1 | PAS domain-containing protein | - |
| JLF32_RS25150 () | 37759..37986 | + | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| JLF32_RS25155 () | 38020..38382 | + | 363 | WP_000338606.1 | type IV conjugative transfer system pilin TraA | - |
| JLF32_RS25160 () | 38387..38698 | + | 312 | WP_000012107.1 | type IV conjugative transfer system protein TraL | - |
| JLF32_RS25165 () | 38772..39469 | + | 698 | Protein_49 | IS1 family transposase IS1G | Transposase |
| JLF32_RS25170 () | 39517..39837 | + | 321 | WP_001348757.1 | conjugal transfer protein TrbA | - |
| JLF32_RS25175 () | 39964..40248 | + | 285 | WP_001617873.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| JLF32_RS25180 () | 40235..40780 | + | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| JLF32_RS25185 () | 40710..41057 | + | 348 | WP_071571857.1 | P-type conjugative transfer protein TrbJ | - |
| JLF32_RS25190 () | 41005..41430 | + | 426 | WP_001348758.1 | F-type conjugal transfer protein TrbF | - |
| JLF32_RS25195 () | 41417..42790 | + | 1374 | WP_000944328.1 | conjugal transfer protein TraH | - |
| JLF32_RS25200 () | 42787..45606 | + | 2820 | WP_001007062.1 | conjugal transfer mating pair stabilization protein TraG | - |
| JLF32_RS25205 () | 45625..46122 | + | 498 | WP_000605862.1 | entry exclusion protein | - |
| JLF32_RS25210 () | 46154..46885 | + | 732 | WP_000850429.1 | complement resistance protein TraT | - |
| JLF32_RS25215 () | 47088..47867 | + | 780 | WP_000199914.1 | hypothetical protein | - |
| JLF32_RS25220 () | 47864..50107 | + | 2244 | WP_077393706.1 | type IV conjugative transfer system coupling protein TraD | - |
| JLF32_RS25225 () | 50107..55377 | + | 5271 | WP_001617867.1 | Multifunctional conjugation protein TraI | Relaxase |
| JLF32_RS25230 () | 55397..56143 | + | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| JLF32_RS25235 () | 56198..56758 | + | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| JLF32_RS25240 () | 56889..57101 | + | 213 | WP_013023861.1 | hypothetical protein | - |
| JLF32_RS25245 () | 57660..58085 | + | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| JLF32_RS25250 () | 58082..58432 | + | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| JLF32_RS25255 () | 58463..60076 | + | 1614 | WP_000080195.1 | IS66 family transposase ISEc23 | Transposase |
| JLF32_RS25260 () | 60154..60440 | + | 287 | Protein_68 | DUF2726 domain-containing protein | - |
| - () | 60407..60467 | - | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 60407..60467 | - | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 60407..60467 | - | 61 | NuclAT_2 | - | Antitoxin Detail |
| - () | 60407..60467 | - | 61 | NuclAT_2 | - | Antitoxin Detail |
| JLF32_RS25265 () | 60512..60646 | + | 135 | WP_023144756.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| JLF32_RS25270 () | 60943..61197 | + | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| JLF32_RS25275 () | 61303..61437 | + | 135 | Protein_71 | protein CopA/IncA | - |
| JLF32_RS25280 () | 61434..61508 | + | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| JLF32_RS25285 () | 61501..62358 | + | 858 | WP_001617855.1 | incFII family plasmid replication initiator RepA | - |
| JLF32_RS25290 () | 63060..63200 | + | 141 | WP_001333237.1 | hypothetical protein | - |
| JLF32_RS25295 () | 63298..63951 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| JLF32_RS25300 () | 64044..64301 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| JLF32_RS25305 () | 64234..64635 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| JLF32_RS25310 () | 64884..65299 | + | 416 | Protein_78 | IS1 family transposase | - |
| JLF32_RS25315 () | 65335..65880 | - | 546 | Protein_79 | Tn3 family transposase TnpA_Tn3 | Transposase |
| JLF32_RS25320 () | 65946..66650 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| JLF32_RS25325 () | 66711..67007 | + | 297 | Protein_81 | replication protein C | - |
| JLF32_RS25330 () | 67195..68010 | + | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| JLF32_RS25335 () | 68071..68874 | + | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| JLF32_RS25340 () | 68874..69710 | + | 837 | WP_000480972.1 | hypothetical protein | ARG |
| JLF32_RS25345 () | 69764..70000 | + | 237 | WP_042005022.1 | hypothetical protein | - |
| JLF32_RS25350 () | 70032..70658 | - | 627 | WP_031606906.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| JLF32_RS25355 () | 70764..71963 | + | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| JLF32_RS25360 () | 71995..72327 | - | 333 | Protein_88 | EamA family transporter | - |
| JLF32_RS25365 () | 72380..73084 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| JLF32_RS25370 () | 73148..73495 | - | 348 | Protein_90 | IS5 family transposase IS903B | Transposase |
| JLF32_RS25375 () | 73530..74405 | - | 876 | WP_032277257.1 | Beta-lactamase CTX-M-97 | ARG |
| JLF32_RS25380 () | 74719..75423 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| JLF32_RS25385 () | 75545..76450 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| JLF32_RS25390 () | 76447..77685 | + | 1239 | WP_000004159.1 | MFS transporter | - |
| JLF32_RS25395 () | 77685..78269 | + | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| JLF32_RS25400 () | 78762..79526 | - | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| JLF32_RS25405 () | 79644..79709 | - | 66 | Protein_97 | EAL domain-containing protein | - |
| JLF32_RS25410 () | 79753..80058 | - | 306 | WP_000130000.1 | hypothetical protein | Relaxase |
| JLF32_RS25415 () | 80069..81274 | - | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| JLF32_RS25420 () | 81430..81633 | - | 204 | WP_000376616.1 | hypothetical protein | - |
| JLF32_RS25425 () | 81761..82600 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| JLF32_RS25430 () | 82594..82941 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| JLF32_RS25435 () | 83147..83935 | - | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| JLF32_RS25440 () | 84066..84539 | - | 474 | WP_001389366.1 | Dihydrofolate reductase type 1 | ARG |
| JLF32_RS25445 () | 84697..85446 | + | 750 | Protein_105 | IS91 family transposase ISAzo26 | Transposase |
| JLF32_RS25450 () | 85505..86209 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| JLF32_RS25455 () | 86262..86716 | - | 455 | Protein_107 | IS1 family transposase | - |
| JLF32_RS25460 () | 86930..90046 | - | 3117 | WP_001553854.1 | HsdR family type I site-specific deoxyribonuclease | - |
| JLF32_RS25465 () | 90168..91439 | - | 1272 | WP_023142242.1 | restriction endonuclease subunit S | - |
| JLF32_RS25470 () | 91436..92992 | - | 1557 | WP_001617892.1 | type I restriction-modification system subunit M | - |
| JLF32_RS25475 () | 93175..93396 | + | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| JLF32_RS25480 () | 93396..93776 | + | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | Toxin Detail |
| JLF32_RS25485 () | 93781..93960 | + | 180 | WP_001513661.1 | hypothetical protein | - |
| JLF32_RS25490 () | 93988..94347 | + | 360 | WP_001513660.1 | hypothetical protein | - |
| JLF32_RS25495 () | 94271..94684 | + | 414 | Protein_115 | DDE-type integrase/transposase/recombinase | - |
| JLF32_RS25500 () | 94634..94951 | - | 318 | WP_001513659.1 | hypothetical protein | - |
| JLF32_RS25505 () | 95179..96195 | - | 1017 | WP_012372828.1 | IS5 family transposase IS5D | Transposase |
| JLF32_RS25510 () | 96403..97806 | + | 1404 | WP_001373486.1 | S-methylmethionine permease | - |
| JLF32_RS25515 () | 97793..98725 | + | 933 | WP_000081352.1 | homocysteine S-methyltransferase | - |
| JLF32_RS25520 () | 98834..99163 | - | 330 | Protein_120 | TOBE domain-containing protein | - |
| JLF32_RS25525 () | 99179..99876 | - | 698 | Protein_121 | IS1 family transposase IS1R | Transposase |
| JLF32_RS25530 () | 99934..100182 | + | 249 | Protein_122 | abortive infection family protein | - |
| JLF32_RS25535 () | 100551..101282 | - | 732 | WP_001617898.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|