MGE detailed information
MGE type: Conjugative plasmid MGE length: 123467 bp
Accession: NZ_AP022526 Location: 1..123467 Organism: Escherichia coli strain THO-003 Replicon: plasmid pTHO-003-1
Accession: NZ_AP022526 Location: 1..123467 Organism: Escherichia coli strain THO-003 Replicon: plasmid pTHO-003-1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JLF28_RS25630 () | 102..359 | + | 258 | WP_000083833.1 | replication regulatory protein RepA | - |
| JLF28_RS25635 () | 595..669 | + | 75 | WP_032336874.1 | RepA leader peptide Tap | - |
| JLF28_RS25640 () | 662..1108 | + | 447 | Protein_2 | incFII family plasmid replication initiator RepA | - |
| JLF28_RS25645 () | 1054..1536 | - | 483 | Protein_3 | VENN motif pre-toxin domain-containing protein | - |
| JLF28_RS25650 () | 2429..3649 | + | 1221 | WP_000410951.1 | arginine deiminase | - |
| JLF28_RS25655 () | 3660..4571 | + | 912 | WP_000440183.1 | carbamate kinase | - |
| JLF28_RS25660 () | 4656..5660 | + | 1005 | WP_000154545.1 | Ornithine carbamoyltransferase | VF |
| JLF28_RS25665 () | 5708..7111 | + | 1404 | WP_000514417.1 | YfcC family protein | - |
| JLF28_RS25670 () | 7192..7671 | + | 480 | WP_001496175.1 | ArgR family transcriptional regulator | - |
| JLF28_RS25675 () | 7735..8076 | - | 342 | Protein_9 | transposase | - |
| JLF28_RS25680 () | 8028..8249 | - | 222 | WP_000080227.1 | IS66 family transposase ISEc43 | Transposase |
| JLF28_RS25685 () | 8280..8630 | - | 351 | WP_000624725.1 | IS66 family transposase ISEc47 | Transposase |
| JLF28_RS25690 () | 8627..8989 | - | 363 | WP_059330006.1 | IS66 family transposase ISEc23 | Transposase |
| JLF28_RS25695 () | 9098..9795 | - | 698 | Protein_13 | IS1 family transposase IS1S | Transposase |
| JLF28_RS25700 () | 9828..10406 | + | 579 | WP_032152936.1 | DUF2726 domain-containing protein | - |
| JLF28_RS25705 () | 10819..11172 | - | 354 | WP_000005489.1 | hypothetical protein | - |
| JLF28_RS25710 () | 11644..12666 | - | 1023 | WP_000156883.1 | IS110 family transposase ISSm1 | Transposase |
| JLF28_RS25715 () | 13071..13328 | + | 258 | WP_000083821.1 | replication regulatory protein RepA | - |
| JLF28_RS25720 () | 13563..13637 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| JLF28_RS25725 () | 13630..14487 | + | 858 | WP_032152935.1 | incFII family plasmid replication initiator RepA | - |
| JLF28_RS25730 () | 15426..16079 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| JLF28_RS25735 () | 16172..16429 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| JLF28_RS25740 () | 16362..16763 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| JLF28_RS25745 () | 16900..19182 | - | 2283 | Protein_23 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| JLF28_RS25750 () | 19236..19940 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| JLF28_RS25755 () | 20273..20992 | + | 720 | Protein_25 | restriction endonuclease | - |
| JLF28_RS25760 () | 21055..21759 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| JLF28_RS25765 () | 21769..21978 | + | 210 | WP_200922648.1 | nitrile hydratase subunit alpha | - |
| JLF28_RS25770 () | 22218..23693 | - | 1476 | WP_020324153.1 | SEC-C domain-containing protein | - |
| JLF28_RS25775 () | 25691..26410 | - | 720 | WP_013263795.1 | replication initiation protein | - |
| JLF28_RS25780 () | 26855..27559 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| JLF28_RS25785 () | 27624..28517 | + | 894 | Protein_31 | translesion error-prone DNA polymerase V subunit MucB | - |
| JLF28_RS25790 () | 28668..29459 | + | 792 | WP_001452808.1 | SprT-like domain-containing protein | - |
| JLF28_RS25795 () | 29474..29815 | - | 342 | WP_000057569.1 | hypothetical protein | - |
| JLF28_RS25800 () | 30054..30758 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| JLF28_RS25805 () | 30798..31358 | + | 561 | WP_101862740.1 | Tn3 family transposase TnpR_ISPa38 | Transposase |
| JLF28_RS25810 () | 32768..33049 | - | 282 | WP_039032642.1 | hypothetical protein | - |
| JLF28_RS25815 () | 33190..34219 | + | 1030 | Protein_37 | translesion error-prone DNA polymerase V subunit UmuC | - |
| JLF28_RS25820 () | 34377..35045 | - | 669 | WP_200922649.1 | SOS response-associated peptidase family protein | - |
| JLF28_RS25825 () | 35112..35335 | - | 224 | Protein_39 | LysR family transcriptional regulator | - |
| JLF28_RS25830 () | 35590..36747 | + | 1158 | WP_200922643.1 | MFS transporter | - |
| JLF28_RS25835 () | 36744..38030 | - | 1287 | WP_200922644.1 | MFS transporter | - |
| JLF28_RS25840 () | 38145..39557 | - | 1413 | WP_200922645.1 | amidase | - |
| JLF28_RS25845 () | 39818..40750 | + | 933 | WP_200922646.1 | helix-turn-helix domain-containing protein | - |
| JLF28_RS25850 () | 40890..41039 | + | 150 | WP_200922647.1 | hypothetical protein | - |
| JLF28_RS25855 () | 41076..41780 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| JLF28_RS25860 () | 41844..42659 | + | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| JLF28_RS25865 () | 43006..44892 | + | 1887 | WP_000118029.1 | FTR1 family iron permease | - |
| JLF28_RS25870 () | 44933..45460 | + | 528 | WP_000178050.1 | iron transporter | - |
| JLF28_RS25875 () | 45564..46943 | + | 1380 | WP_000119836.1 | DUF2318 domain-containing protein | - |
| JLF28_RS25880 () | 46946..48229 | + | 1284 | WP_000964653.1 | ABC transporter permease | - |
| JLF28_RS25885 () | 48219..49349 | + | 1131 | WP_000729219.1 | ABC transporter permease | - |
| JLF28_RS25890 () | 49354..50049 | + | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| JLF28_RS25895 () | 50036..50521 | + | 486 | WP_001267176.1 | TlpA family protein disulfide reductase | - |
| JLF28_RS25900 () | 50546..51031 | + | 486 | WP_000874189.1 | hypothetical protein | - |
| JLF28_RS25905 () | 51153..51785 | + | 633 | Protein_55 | histidine-type phosphatase | - |
| JLF28_RS25910 () | 51935..52039 | - | 105 | Protein_56 | IS5/IS1182 family transposase | - |
| JLF28_RS25915 () | 52073..54487 | - | 2415 | Protein_57 | Tn3 family transposase TnpA_ISSba14 | Transposase |
| JLF28_RS25920 () | 54545..55249 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| JLF28_RS25925 () | 55303..55644 | - | 342 | Protein_59 | DNA helicase UvrD | - |
| JLF28_RS25930 () | 55629..57194 | - | 1566 | WP_001128474.1 | AAA family ATPase | - |
| JLF28_RS25935 () | 57269..57685 | - | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| JLF28_RS25940 () | 57682..57912 | - | 231 | WP_001261286.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| JLF28_RS25945 () | 58472..58690 | + | 219 | WP_000813630.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| JLF28_RS25950 () | 58692..58997 | + | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| JLF28_RS25955 () | 58998..59804 | + | 807 | WP_000016970.1 | site-specific integrase | - |
| JLF28_RS25960 () | 60526..61281 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| JLF28_RS25965 () | 61869..63035 | + | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| JLF28_RS25970 () | 63035..64006 | + | 972 | WP_000817031.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| JLF28_RS25975 () | 64744..65646 | + | 903 | WP_064766247.1 | DUF1281 domain-containing protein | - |
| JLF28_RS25980 () | 65650..65954 | + | 305 | Protein_70 | hypothetical protein | - |
| JLF28_RS25985 () | 66031..66714 | + | 684 | WP_032181561.1 | DNA methylase | - |
| JLF28_RS25990 () | 66715..66936 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| JLF28_RS25995 () | 66950..67384 | + | 435 | WP_001546462.1 | DUF1380 family protein | - |
| JLF28_RS26000 () | 67429..68199 | + | 771 | WP_001006251.1 | hypothetical protein | - |
| JLF28_RS26005 () | 68736..69038 | + | 303 | WP_001666994.1 | antirestriction protein | - |
| JLF28_RS26010 () | 69085..69507 | + | 423 | WP_000271685.1 | DUF1380 family protein | - |
| JLF28_RS26015 () | 69504..69695 | + | 192 | WP_001027495.1 | hypothetical protein | - |
| JLF28_RS26020 () | 69967..70215 | - | 249 | WP_071781657.1 | hypothetical protein | - |
| JLF28_RS26025 () | 70727..70957 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| JLF28_RS26030 () | 71009..72370 | + | 1362 | WP_000199439.1 | DUF3560 domain-containing protein | - |
| JLF28_RS26035 () | 72418..72983 | + | 566 | Protein_81 | class I SAM-dependent methyltransferase | - |
| JLF28_RS26040 () | 73009..73221 | + | 213 | WP_001348622.1 | hypothetical protein | - |
| JLF28_RS26045 () | 73631..73837 | + | 207 | WP_000275856.1 | hypothetical protein | - |
| JLF28_RS26050 () | 74515..76416 | + | 1902 | WP_000936285.1 | group II intron reverse transcriptase/maturase | - |
| JLF28_RS26055 () | 76566..77063 | + | 498 | WP_042039995.1 | single-stranded DNA-binding protein | - |
| JLF28_RS26060 () | 77131..77364 | + | 234 | WP_000005990.1 | DUF905 family protein | - |
| JLF28_RS26065 () | 77392..77589 | + | 198 | Protein_87 | hypothetical protein | - |
| JLF28_RS26070 () | 77644..78078 | + | 435 | WP_000845937.1 | conjugation system SOS inhibitor PsiB | - |
| JLF28_RS26075 () | 78075..78794 | + | 720 | WP_001276238.1 | plasmid SOS inhibition protein A | - |
| JLF28_RS26080 () | 78806..78994 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - () | 78806..79003 | + | 198 | NuclAT_0 | - | - |
| - () | 78806..79003 | + | 198 | NuclAT_0 | - | - |
| - () | 78806..79003 | + | 198 | NuclAT_0 | - | - |
| - () | 78806..79003 | + | 198 | NuclAT_0 | - | - |
| JLF28_RS26085 () | 79051..80420 | + | 1370 | WP_085947770.1 | IS3-like element IS150 family transposase | - |
| - () | 80445..80476 | + | 32 | NuclAT_1 | - | Antitoxin Detail |
| - () | 80445..80476 | + | 32 | NuclAT_1 | - | Antitoxin Detail |
| - () | 80445..80476 | + | 32 | NuclAT_1 | - | Antitoxin Detail |
| - () | 80445..80476 | + | 32 | NuclAT_1 | - | Antitoxin Detail |
| JLF28_RS26090 () | 80520..80678 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| JLF28_RS26095 () | 81011..82624 | - | 1614 | WP_000080195.1 | IS66 family transposase ISEc23 | Transposase |
| JLF28_RS26100 () | 82655..83005 | - | 351 | WP_000624722.1 | IS66 family transposase ISEc23 | Transposase |
| JLF28_RS26105 () | 83002..83427 | - | 426 | WP_000422741.1 | IS66 family transposase ISEc23 | Transposase |
| JLF28_RS26110 () | 84139..84426 | + | 288 | WP_000107535.1 | hypothetical protein | - |
| JLF28_RS26115 () | 84544..85365 | + | 822 | WP_001234426.1 | DUF945 domain-containing protein | - |
| JLF28_RS26120 () | 85662..86264 | - | 603 | WP_013362798.1 | hypothetical protein | VF |
| JLF28_RS26125 () | 86585..86968 | + | 384 | WP_001151524.1 | relaxosome protein TraM | - |
| JLF28_RS26130 () | 87155..87844 | + | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| JLF28_RS26135 () | 87943..88338 | + | 396 | WP_001309237.1 | conjugal transfer relaxosome protein TraY | - |
| JLF28_RS26140 () | 88371..88736 | + | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| JLF28_RS26145 () | 88751..89062 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| JLF28_RS26150 () | 89084..89650 | + | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| JLF28_RS26155 () | 89661..90365 | + | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| JLF28_RS26160 () | 90365..91792 | + | 1428 | WP_000146685.1 | conjugal transfer protein TraB | - |
| JLF28_RS26165 () | 91782..92372 | + | 591 | WP_000002787.1 | conjugal transfer protein TraP | - |
| JLF28_RS26170 () | 92326..92556 | + | 231 | WP_001352845.1 | conjugal transfer protein TrbD | - |
| JLF28_RS26175 () | 92568..92819 | + | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| JLF28_RS26180 () | 92816..93331 | + | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| JLF28_RS26185 () | 93466..93687 | + | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| JLF28_RS26190 () | 93847..96474 | + | 2628 | WP_001064245.1 | type IV secretion system protein TraC | - |
| JLF28_RS26195 () | 96471..96857 | + | 387 | WP_000099686.1 | type-F conjugative transfer system protein TrbI | - |
| JLF28_RS26200 () | 96854..97486 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| JLF28_RS26205 () | 97483..98475 | + | 993 | WP_000830180.1 | conjugal transfer pilus assembly protein TraU | - |
| JLF28_RS26210 () | 98484..99122 | + | 639 | WP_021518374.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| JLF28_RS26215 () | 99119..100927 | + | 1809 | WP_000821840.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| JLF28_RS26220 () | 100954..101211 | + | 258 | WP_000864312.1 | conjugal transfer protein TrbE | - |
| JLF28_RS26225 () | 101204..101947 | + | 744 | WP_001030378.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| JLF28_RS26230 () | 101961..102302 | + | 342 | WP_000556794.1 | conjugal transfer protein TrbA | - |
| JLF28_RS26235 () | 102283..102618 | - | 336 | WP_000415571.1 | hypothetical protein | - |
| JLF28_RS26240 () | 102699..102983 | + | 285 | WP_000624105.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| JLF28_RS26245 () | 102970..103524 | + | 555 | WP_001553830.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| JLF28_RS26250 () | 103454..103828 | + | 375 | WP_071788165.1 | P-type conjugative transfer protein TrbJ | - |
| JLF28_RS26255 () | 103782..104174 | + | 393 | WP_000164675.1 | F-type conjugal transfer protein TrbF | - |
| JLF28_RS26260 () | 104161..105534 | + | 1374 | WP_021518370.1 | conjugal transfer protein TraH | - |
| JLF28_RS26265 () | 105531..108356 | + | 2826 | WP_001553826.1 | conjugal transfer mating pair stabilization protein TraG | - |
| JLF28_RS26270 () | 108353..108862 | + | 510 | WP_000628100.1 | conjugal transfer entry exclusion protein TraS | - |
| JLF28_RS26275 () | 108876..109607 | + | 732 | WP_000850424.1 | complement resistance protein TraT | - |
| JLF28_RS26280 () | 109859..112048 | + | 2190 | WP_040110343.1 | type IV conjugative transfer system coupling protein TraD | - |
| JLF28_RS26285 () | 112048..117168 | + | 5121 | WP_013362805.1 | Multifunctional conjugation protein TraI | Relaxase |
| JLF28_RS26290 () | 117188..117934 | + | 747 | WP_023149624.1 | conjugal transfer pilus acetylase TraX | - |
| JLF28_RS26295 () | 117989..118549 | + | 561 | WP_000139363.1 | fertility inhibition protein FinO | - |
| JLF28_RS26300 () | 118683..118895 | + | 213 | WP_005012601.1 | hypothetical protein | - |
| JLF28_RS26305 () | 119196..119285 | - | 90 | Protein_135 | IS1 family transposase | - |
| JLF28_RS26310 () | 119340..120017 | + | 678 | WP_001339397.1 | IS66 family transposase ISCro1 | Transposase |
| JLF28_RS26315 () | 120017..120364 | + | 348 | WP_000624622.1 | IS66 family transposase ISCro1 | Transposase |
| JLF28_RS26320 () | 120384..121955 | + | 1572 | WP_023149734.1 | IS66 family transposase ISCro1 | Transposase |
| JLF28_RS26325 () | 121993..122609 | - | 617 | Protein_139 | IS1 family transposase IS1G | Transposase |
| JLF28_RS26330 () | 122710..122892 | + | 183 | WP_000968309.1 | hypothetical protein | - |
| - () | 123031..123092 | - | 62 | NuclAT_2 | - | - |
| - () | 123031..123092 | - | 62 | NuclAT_2 | - | - |
| - () | 123031..123092 | - | 62 | NuclAT_2 | - | - |
| - () | 123031..123092 | - | 62 | NuclAT_2 | - | - |
| JLF28_RS26335 () | 123079..123285 | + | 207 | WP_015387399.1 | type I toxin-antitoxin system Hok family toxin | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|