MGE detailed information
MGE type: Conjugative plasmid MGE length: 67915 bp
Accession: NZ_AP022328 Location: 1..67915 Organism: Escherichia coli O25:H4 strain 18044 Replicon: plasmid p18044_2
Accession: NZ_AP022328 Location: 1..67915 Organism: Escherichia coli O25:H4 strain 18044 Replicon: plasmid p18044_2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ECO25NV_RS25330 () | 34..108 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| ECO25NV_RS25335 () | 101..958 | + | 858 | WP_181717161.1 | incFII family plasmid replication initiator RepA | - |
| ECO25NV_RS25340 () | 1659..1871 | + | 213 | WP_032155400.1 | hypothetical protein | - |
| ECO25NV_RS25345 () | 1986..2294 | - | 309 | Protein_3 | IS91 family transposase ISSbo1 | Transposase |
| ECO25NV_RS25350 () | 2487..2585 | + | 99 | WP_137491101.1 | transposase | - |
| ECO25NV_RS25355 () | 2735..2983 | - | 249 | WP_000738203.1 | hypothetical protein | - |
| ECO25NV_RS25360 () | 3013..3783 | - | 771 | WP_000712166.1 | molybdopterin-dependent oxidoreductase | - |
| ECO25NV_RS25365 () | 3794..4393 | - | 600 | WP_001177183.1 | cytochrome b/b6 domain-containing protein | - |
| ECO25NV_RS25370 () | 4535..5257 | + | 723 | WP_001057737.1 | Transcriptional regulatory protein WalR | VF |
| ECO25NV_RS25375 () | 5254..6726 | + | 1473 | WP_000621194.1 | sensor histidine kinase | - |
| ECO25NV_RS25380 () | 7104..7271 | - | 168 | Protein_10 | IS110 family transposase | - |
| ECO25NV_RS25385 () | 7325..8036 | - | 712 | Protein_11 | IS6 family transposase IS26 | Transposase |
| ECO25NV_RS25390 () | 8102..8533 | + | 432 | WP_001707302.1 | hypothetical protein | - |
| ECO25NV_RS25395 () | 8530..9321 | + | 792 | WP_000016494.1 | site-specific integrase | - |
| ECO25NV_RS25400 () | 9459..9734 | - | 276 | WP_000239529.1 | hypothetical protein | - |
| ECO25NV_RS25405 () | 9728..10372 | - | 645 | WP_000633913.1 | AAA family ATPase | - |
| ECO25NV_RS25410 () | 10601..11572 | + | 972 | WP_001103690.1 | hypothetical protein | - |
| ECO25NV_RS25415 () | 11577..11969 | + | 393 | WP_000340829.1 | plasmid partitioning/stability family protein | - |
| ECO25NV_RS25420 () | 11974..13245 | - | 1272 | WP_000457518.1 | Y-family DNA polymerase | - |
| ECO25NV_RS25425 () | 13245..13682 | - | 438 | WP_097498060.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| ECO25NV_RS25430 () | 13679..13927 | - | 249 | WP_000618105.1 | DinI-like family protein | - |
| ECO25NV_RS25435 () | 14345..15280 | + | 936 | Protein_21 | DUF1281 domain-containing protein | - |
| ECO25NV_RS25440 () | 15512..15742 | + | 231 | WP_072131853.1 | hypothetical protein | - |
| ECO25NV_RS25445 () | 15794..17155 | + | 1362 | WP_181717157.1 | DUF3560 domain-containing protein | - |
| ECO25NV_RS25450 () | 17203..17766 | + | 564 | WP_001315564.1 | class I SAM-dependent methyltransferase | - |
| ECO25NV_RS25455 () | 17792..18013 | + | 222 | WP_042111886.1 | hypothetical protein | - |
| ECO25NV_RS25460 () | 18176..18511 | + | 336 | WP_077763704.1 | hypothetical protein | - |
| ECO25NV_RS25465 () | 18424..18630 | + | 207 | WP_000275853.1 | hypothetical protein | - |
| ECO25NV_RS25470 () | 18656..19195 | + | 540 | WP_097498141.1 | single-stranded DNA-binding protein | - |
| ECO25NV_RS25475 () | 19258..19492 | + | 235 | Protein_29 | DUF905 family protein | - |
| ECO25NV_RS25480 () | 19558..21516 | + | 1959 | WP_000117163.1 | ParB/RepB/Spo0J family partition protein | - |
| ECO25NV_RS25485 () | 21571..22005 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| ECO25NV_RS25490 () | 22002..22721 | + | 720 | WP_052925806.1 | plasmid SOS inhibition protein A | - |
| ECO25NV_RS25495 () | 22733..22921 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - () | 22733..22957 | + | 225 | NuclAT_0 | - | - |
| - () | 22733..22957 | + | 225 | NuclAT_0 | - | - |
| - () | 22733..22957 | + | 225 | NuclAT_0 | - | - |
| - () | 22733..22957 | + | 225 | NuclAT_0 | - | - |
| ECO25NV_RS25500 () | 23001..23159 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| ECO25NV_RS25505 () | 23562..24212 | + | 651 | WP_001487415.1 | IS66 family transposase IS679 | Transposase |
| ECO25NV_RS25510 () | 24212..24559 | + | 348 | WP_000624618.1 | IS66 family transposase ISCro1 | Transposase |
| ECO25NV_RS25515 () | 24579..26150 | + | 1572 | WP_199805184.1 | IS66 family transposase IS679 | Transposase |
| ECO25NV_RS25520 () | 26768..27064 | + | 297 | WP_001272251.1 | hypothetical protein | - |
| ECO25NV_RS25525 () | 27175..27996 | + | 822 | WP_001234445.1 | DUF945 domain-containing protein | - |
| ECO25NV_RS25530 () | 28293..28883 | - | 591 | WP_000252683.1 | hypothetical protein | VF |
| ECO25NV_RS25535 () | 29216..29599 | + | 384 | WP_001151529.1 | relaxosome protein TraM | - |
| ECO25NV_RS25540 () | 29791..30438 | + | 648 | WP_000332523.1 | transcriptional regulator TraJ family protein | - |
| ECO25NV_RS25545 () | 30546..30785 | + | 240 | WP_042018283.1 | conjugal transfer relaxosome protein TraY | - |
| ECO25NV_RS25550 () | 30819..31181 | + | 363 | WP_012881131.1 | type IV conjugative transfer system pilin TraA | - |
| ECO25NV_RS25555 () | 31196..31507 | + | 312 | WP_000012100.1 | type IV conjugative transfer system protein TraL | - |
| ECO25NV_RS25560 () | 31529..32095 | + | 567 | WP_000399780.1 | type IV conjugative transfer system protein TraE | - |
| ECO25NV_RS25565 () | 32082..32810 | + | 729 | WP_001230769.1 | type-F conjugative transfer system secretin TraK | - |
| ECO25NV_RS25570 () | 32810..34237 | + | 1428 | WP_012881130.1 | conjugal transfer protein TraB | - |
| ECO25NV_RS25575 () | 34227..34817 | + | 591 | WP_012881129.1 | conjugal transfer protein TraP | - |
| ECO25NV_RS25580 () | 34756..35124 | + | 369 | WP_001681801.1 | conjugal transfer protein TrbD | - |
| ECO25NV_RS25585 () | 35121..35636 | + | 516 | WP_000809881.1 | type IV conjugative transfer system lipoprotein TraV | - |
| ECO25NV_RS25590 () | 35771..35992 | + | 222 | WP_001278683.1 | conjugal transfer protein TraR | - |
| ECO25NV_RS25595 () | 35985..36461 | + | 477 | WP_012881127.1 | hypothetical protein | - |
| ECO25NV_RS25600 () | 36560..36778 | + | 219 | WP_000556745.1 | hypothetical protein | - |
| ECO25NV_RS25605 () | 36806..37153 | + | 348 | WP_000836682.1 | hypothetical protein | - |
| ECO25NV_RS25610 () | 37279..39909 | + | 2631 | WP_000069772.1 | type IV secretion system protein TraC | - |
| ECO25NV_RS25615 () | 39906..40292 | + | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| ECO25NV_RS25620 () | 40289..40921 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| ECO25NV_RS25625 () | 40918..41910 | + | 993 | WP_000830849.1 | conjugal transfer pilus assembly protein TraU | - |
| ECO25NV_RS25630 () | 41940..42245 | + | 306 | WP_000224418.1 | hypothetical protein | - |
| ECO25NV_RS25635 () | 42254..42892 | + | 639 | WP_012881126.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| ECO25NV_RS25640 () | 42889..44739 | + | 1851 | WP_012881125.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| ECO25NV_RS25645 () | 44766..45023 | + | 258 | WP_000864353.1 | conjugal transfer protein TrbE | - |
| ECO25NV_RS25650 () | 45016..45759 | + | 744 | WP_001030371.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| ECO25NV_RS25655 () | 45773..46114 | + | 342 | WP_000556795.1 | conjugal transfer protein TrbA | - |
| ECO25NV_RS25660 () | 46095..46430 | - | 336 | WP_000736414.1 | hypothetical protein | - |
| ECO25NV_RS25665 () | 46511..46795 | + | 285 | WP_000624107.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| ECO25NV_RS25670 () | 46782..47327 | + | 546 | WP_000059830.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| ECO25NV_RS25675 () | 47257..47604 | + | 348 | WP_011666494.1 | P-type conjugative transfer protein TrbJ | - |
| ECO25NV_RS25680 () | 47552..47977 | + | 426 | WP_001348758.1 | F-type conjugal transfer protein TrbF | - |
| ECO25NV_RS25685 () | 47964..49337 | + | 1374 | WP_139570830.1 | conjugal transfer protein TraH | - |
| ECO25NV_RS25690 () | 49334..52159 | + | 2826 | WP_139570829.1 | conjugal transfer mating pair stabilization protein TraG | - |
| ECO25NV_RS25695 () | 52156..52665 | + | 510 | WP_000628111.1 | conjugal transfer entry exclusion protein TraS | - |
| ECO25NV_RS25700 () | 52679..53410 | + | 732 | WP_012881123.1 | complement resistance protein TraT | - |
| ECO25NV_RS25705 () | 53613..54350 | + | 738 | WP_012881122.1 | hypothetical protein | - |
| ECO25NV_RS25710 () | 54401..56599 | + | 2199 | WP_025746094.1 | type IV conjugative transfer system coupling protein TraD | - |
| ECO25NV_RS25715 () | 56599..61869 | + | 5271 | WP_060578160.1 | Multifunctional conjugation protein TraI | Relaxase |
| ECO25NV_RS25720 () | 61889..62635 | + | 747 | WP_060578161.1 | conjugal transfer pilus acetylase TraX | - |
| ECO25NV_RS25725 () | 62694..63554 | + | 861 | WP_000704523.1 | putative protein YcjY | VF |
| ECO25NV_RS25730 () | 63657..64217 | + | 561 | WP_000139321.1 | fertility inhibition protein FinO | - |
| ECO25NV_RS25735 () | 64346..64558 | + | 213 | WP_001309245.1 | ANR family transcriptional regulator | - |
| ECO25NV_RS25740 () | 64803..65264 | + | 462 | WP_001233838.1 | thermonuclease family protein | - |
| ECO25NV_RS25745 () | 65310..65519 | + | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| ECO25NV_RS25750 () | 65557..66147 | + | 591 | WP_033807967.1 | DUF2726 domain-containing protein | - |
| ECO25NV_RS25755 () | 66302..66775 | + | 474 | WP_016240489.1 | hypothetical protein | - |
| - () | 66918..66977 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 66918..66977 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 66918..66977 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 66918..66977 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| ECO25NV_RS25760 () | 67022..67171 | + | 150 | WP_001312851.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| ECO25NV_RS25765 () | 67456..67704 | + | 249 | WP_000083839.1 | replication regulatory protein RepA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|