MGE detailed information
MGE type: Conjugative plasmid MGE length: 105973 bp
Accession: NZ_AP021934 Location: 1..105973 Organism: Escherichia coli strain WP2-W18-ESBL-08 Replicon: plasmid pWP2-W18-ESBL-08_1
Accession: NZ_AP021934 Location: 1..105973 Organism: Escherichia coli strain WP2-W18-ESBL-08 Replicon: plasmid pWP2-W18-ESBL-08_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H7R10_RS23315 () | 101..1054 | + | 954 | WP_000280980.1 | Protease 7 | VF |
| H7R10_RS23320 () | 1487..2596 | + | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| H7R10_RS23325 () | 2665..3567 | + | 903 | WP_001312822.1 | hypothetical protein | VF |
| H7R10_RS23330 () | 3941..4129 | + | 189 | WP_001324033.1 | hypothetical protein | - |
| H7R10_RS23335 () | 4250..4990 | + | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| H7R10_RS23340 () | 5275..6252 | - | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| H7R10_RS23345 () | 6998..7321 | + | 324 | Protein_6 | IS21 family transposase IS21 | Transposase |
| H7R10_RS23350 () | 7323..7427 | + | 105 | Protein_7 | AAA family ATPase | - |
| H7R10_RS23355 () | 7488..8001 | + | 514 | Protein_8 | DUF4113 domain-containing protein | - |
| H7R10_RS23360 () | 8181..8878 | - | 698 | Protein_9 | IS1 family transposase | - |
| H7R10_RS23365 () | 9234..10148 | + | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| H7R10_RS23370 () | 10148..10975 | + | 828 | WP_000983710.1 | Vitamin B12 import ATP-binding protein BtuD | VF |
| H7R10_RS23375 () | 10972..11829 | + | 858 | WP_001101723.1 | hypothetical protein | ARG |
| H7R10_RS23380 () | 11826..12683 | + | 858 | WP_000968139.1 | hypothetical protein | ARG |
| H7R10_RS23385 () | 12917..13174 | - | 258 | Protein_14 | Tn3 family transposase | - |
| H7R10_RS23390 () | 13172..13585 | + | 414 | Protein_15 | phosphopyruvate hydratase | - |
| H7R10_RS23395 () | 13926..14306 | + | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| H7R10_RS23400 () | 14686..15879 | - | 1194 | WP_000095526.1 | MFS transporter | - |
| H7R10_RS23405 () | 16015..17739 | + | 1725 | WP_000602863.1 | hypothetical protein | VF |
| H7R10_RS23410 () | 17740..18687 | + | 948 | WP_000011910.1 | hypothetical protein | VF |
| H7R10_RS23415 () | 18687..20429 | + | 1743 | WP_001015721.1 | hypothetical protein | VF |
| H7R10_RS23420 () | 20426..21703 | + | 1278 | WP_000750130.1 | Ferredoxin--NADP reductase | VF |
| H7R10_RS23425 () | 21785..23986 | + | 2202 | WP_000973520.1 | Vitamin B12 transporter BtuB | VF |
| H7R10_RS23430 () | 24471..25168 | + | 698 | Protein_23 | IS1-like element IS1A family transposase | - |
| H7R10_RS23435 () | 25468..26634 | + | 1167 | WP_001238646.1 | Sporulation initiation inhibitor protein Soj | VF |
| H7R10_RS23440 () | 26634..27605 | + | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| H7R10_RS23445 () | 28744..28950 | + | 207 | WP_000275856.1 | hypothetical protein | - |
| H7R10_RS23450 () | 28976..29515 | + | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
| H7R10_RS23455 () | 29583..29816 | + | 234 | WP_000005987.1 | DUF905 family protein | - |
| H7R10_RS23460 () | 29844..30041 | + | 198 | Protein_29 | hypothetical protein | - |
| H7R10_RS23465 () | 30096..30530 | + | 435 | WP_000845936.1 | conjugation system SOS inhibitor PsiB | - |
| H7R10_RS23470 () | 30527..31246 | + | 720 | WP_001276238.1 | plasmid SOS inhibition protein A | - |
| H7R10_RS23475 () | 31258..31446 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - () | 31258..31482 | + | 225 | NuclAT_0 | - | - |
| - () | 31258..31482 | + | 225 | NuclAT_0 | - | - |
| - () | 31258..31482 | + | 225 | NuclAT_0 | - | - |
| - () | 31258..31482 | + | 225 | NuclAT_0 | - | - |
| H7R10_RS23480 () | 31526..31684 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| H7R10_RS23485 () | 32605..32892 | + | 288 | WP_000107535.1 | hypothetical protein | - |
| H7R10_RS23490 () | 33010..33831 | + | 822 | WP_001234426.1 | DUF945 domain-containing protein | - |
| H7R10_RS23495 () | 34128..34730 | - | 603 | WP_000243712.1 | hypothetical protein | VF |
| H7R10_RS23500 () | 35051..35434 | + | 384 | WP_001151524.1 | relaxosome protein TraM | - |
| H7R10_RS23505 () | 35621..36310 | + | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| H7R10_RS23510 () | 36409..36804 | + | 396 | WP_001309237.1 | conjugal transfer relaxosome protein TraY | - |
| H7R10_RS23515 () | 36837..37202 | + | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| H7R10_RS23520 () | 37217..37528 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| H7R10_RS23525 () | 37550..38116 | + | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| H7R10_RS23530 () | 38127..38831 | + | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| H7R10_RS23535 () | 38831..40258 | + | 1428 | WP_000146685.1 | conjugal transfer protein TraB | - |
| H7R10_RS23540 () | 40248..40838 | + | 591 | WP_001376242.1 | conjugal transfer protein TraP | - |
| H7R10_RS23545 () | 40792..41022 | + | 231 | WP_001352845.1 | conjugal transfer protein TrbD | - |
| H7R10_RS23550 () | 41034..41285 | + | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| H7R10_RS23555 () | 41282..41797 | + | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| H7R10_RS23560 () | 41932..42153 | + | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| H7R10_RS23565 () | 42313..44940 | + | 2628 | WP_001064245.1 | type IV secretion system protein TraC | - |
| H7R10_RS23570 () | 44937..45323 | + | 387 | WP_000099686.1 | type-F conjugative transfer system protein TrbI | - |
| H7R10_RS23575 () | 45320..45952 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| H7R10_RS23580 () | 45949..46941 | + | 993 | WP_000830183.1 | conjugal transfer pilus assembly protein TraU | - |
| H7R10_RS23585 () | 46950..47588 | + | 639 | WP_000777700.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| H7R10_RS23590 () | 47585..49393 | + | 1809 | WP_000821841.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| H7R10_RS23595 () | 49420..49677 | + | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| H7R10_RS23600 () | 49670..50413 | + | 744 | WP_001030393.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| H7R10_RS23605 () | 50429..50776 | + | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| H7R10_RS23610 () | 50778..51092 | - | 315 | WP_001324103.1 | hypothetical protein | - |
| H7R10_RS23615 () | 51173..51457 | + | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| H7R10_RS23620 () | 51444..51989 | + | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| H7R10_RS23625 () | 51919..52260 | + | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| H7R10_RS23630 () | 52214..52627 | + | 414 | WP_001324104.1 | F-type conjugal transfer protein TrbF | - |
| H7R10_RS23635 () | 52627..54000 | + | 1374 | WP_001517790.1 | conjugal transfer protein TraH | - |
| H7R10_RS23640 () | 53997..56819 | + | 2823 | WP_001007018.1 | conjugal transfer mating pair stabilization protein TraG | - |
| H7R10_RS23645 () | 56835..57332 | + | 498 | WP_000605857.1 | entry exclusion protein | - |
| H7R10_RS23650 () | 57364..58095 | + | 732 | WP_023565183.1 | complement resistance protein TraT | - |
| H7R10_RS23655 () | 58348..60501 | + | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
| H7R10_RS23660 () | 60510..60908 | - | 399 | WP_000911313.1 | tRNA(fMet)-specific endonuclease VapC | Toxin Detail |
| H7R10_RS23665 () | 60908..61135 | - | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| H7R10_RS23670 () | 61217..66487 | + | 5271 | WP_000986962.1 | Multifunctional conjugation protein TraI | Relaxase |
| H7R10_RS23675 () | 66507..67253 | + | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| H7R10_RS23680 () | 67312..68172 | + | 861 | WP_000704514.1 | hypothetical protein | VF |
| H7R10_RS23685 () | 68275..68835 | + | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| H7R10_RS23690 () | 68971..69183 | + | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| H7R10_RS23695 () | 69429..69503 | + | 75 | Protein_76 | endonuclease | - |
| - () | 69759..69820 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 69759..69820 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 69759..69820 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 69759..69820 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| H7R10_RS23700 () | 69807..70013 | + | 207 | WP_001351576.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| H7R10_RS23705 () | 70297..70554 | + | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| H7R10_RS23710 () | 70786..70860 | + | 75 | WP_001442103.1 | RepA leader peptide Tap | - |
| H7R10_RS23715 () | 70853..71335 | + | 483 | WP_001273588.1 | hypothetical protein | - |
| H7R10_RS23720 () | 71328..72185 | + | 858 | WP_000774297.1 | incFII family plasmid replication initiator RepA | - |
| H7R10_RS23725 () | 73124..73777 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| H7R10_RS23730 () | 73870..74127 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| H7R10_RS23735 () | 74060..74461 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| H7R10_RS23740 () | 74746..76056 | + | 1311 | WP_001262765.1 | DUF262 domain-containing protein | - |
| H7R10_RS23745 () | 76085..76183 | + | 99 | Protein_86 | IS1 family transposase | - |
| H7R10_RS23750 () | 76333..77193 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| H7R10_RS23755 () | 77325..78029 | + | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| H7R10_RS23760 () | 78083..80212 | + | 2130 | Protein_89 | AAA family ATPase | - |
| H7R10_RS23765 () | 80212..80838 | + | 627 | WP_000434930.1 | hypothetical protein | - |
| H7R10_RS23770 () | 80902..81093 | + | 192 | Protein_91 | transposase | - |
| H7R10_RS23775 () | 81343..82218 | + | 876 | WP_013188475.1 | hypothetical protein | ARG |
| H7R10_RS23780 () | 82253..83221 | + | 969 | WP_013362812.1 | IS5 family transposase IS903B | Transposase |
| H7R10_RS23785 () | 83278..84375 | + | 1098 | Protein_94 | TonB-dependent receptor | - |
| H7R10_RS23790 () | 84443..84979 | - | 537 | Protein_95 | PAS domain-containing protein | - |
| H7R10_RS23795 () | 85244..85705 | + | 462 | Protein_96 | Tn3 family transposase TnpR_TnAs2 | Transposase |
| H7R10_RS23800 () | 85758..86462 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| H7R10_RS23805 () | 86523..86699 | + | 177 | Protein_98 | replication protein C | - |
| H7R10_RS23810 () | 87007..87822 | + | 816 | WP_001043260.1 | hypothetical protein | ARG |
| H7R10_RS23815 () | 87883..88686 | + | 804 | WP_001082319.1 | hypothetical protein | ARG |
| H7R10_RS23820 () | 88686..89522 | + | 837 | WP_000480972.1 | hypothetical protein | ARG |
| H7R10_RS23825 () | 89576..89812 | + | 237 | WP_042005022.1 | hypothetical protein | - |
| H7R10_RS23830 () | 89844..90494 | - | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| H7R10_RS23835 () | 90600..91799 | + | 1200 | WP_000804064.1 | Multidrug resistance protein MdtG | ARG |
| H7R10_RS23840 () | 91831..92691 | - | 861 | WP_000493383.1 | EamA family transporter | - |
| H7R10_RS23845 () | 92700..92930 | - | 231 | Protein_106 | transposase | - |
| H7R10_RS23850 () | 92995..93699 | - | 705 | Protein_107 | IS6 family transposase | - |
| H7R10_RS23855 () | 93906..94105 | + | 200 | Protein_108 | lysis protein | - |
| H7R10_RS23860 () | 94163..94456 | - | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| H7R10_RS23865 () | 95083..96311 | + | 1229 | WP_088130945.1 | IS3 family transposase IS2 | Transposase |
| H7R10_RS23870 () | 97534..98727 | + | 1194 | WP_000450494.1 | GTP-binding protein | - |
| H7R10_RS23875 () | 98905..99054 | + | 150 | Protein_112 | IS3 family transposase IS2 | Transposase |
| H7R10_RS23880 () | 99584..100684 | + | 1101 | WP_072714138.1 | hypothetical protein | - |
| H7R10_RS23885 () | 100674..101159 | + | 486 | WP_001015823.1 | hypothetical protein | - |
| H7R10_RS23890 () | 101162..102988 | + | 1827 | WP_001339650.1 | AAA family ATPase | - |
| H7R10_RS23895 () | 103129..103410 | + | 282 | WP_072834405.1 | hypothetical protein | - |
| H7R10_RS23900 () | 103404..104101 | - | 698 | Protein_117 | IS1 family transposase IS1G | Transposase |
| H7R10_RS23905 () | 104157..104459 | - | 303 | Protein_118 | IS3 family transposase IS1203 | Transposase |
| H7R10_RS23910 () | 104643..104801 | + | 159 | WP_001324039.1 | integrase core domain-containing protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|