MGE detailed information
MGE type: Conjugative plasmid MGE length: 123767 bp
Accession: NZ_AP019804 Location: 1..123767 Organism: Escherichia coli strain KY 1497 Replicon: plasmid pKY1497_1
Accession: NZ_AP019804 Location: 1..123767 Organism: Escherichia coli strain KY 1497 Replicon: plasmid pKY1497_1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ECKY1497_RS24735 (1) | 1..858 | + | 858 | WP_029702152.1 | incFII family plasmid replication initiator RepA | - |
| ECKY1497_RS24740 (1559) | 1559..1699 | + | 141 | WP_001333237.1 | hypothetical protein | - |
| ECKY1497_RS24745 (1797) | 1797..2450 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| ECKY1497_RS24750 (2543) | 2543..2800 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| ECKY1497_RS24755 (2733) | 2733..3134 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| ECKY1497_RS24760 (3383) | 3383..3798 | + | 416 | Protein_5 | IS1-like element IS1B family transposase | - |
| ECKY1497_RS24765 (3834) | 3834..4379 | - | 546 | Protein_6 | Tn3 family transposase TnpA_Tn3 | Transposase |
| ECKY1497_RS24770 (4445) | 4445..5149 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ECKY1497_RS24775 (5214) | 5214..5894 | - | 681 | Protein_8 | IS91 family transposase ISAzo26 | Transposase |
| ECKY1497_RS24780 (6039) | 6039..6536 | + | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| ECKY1497_RS24785 (6648) | 6648..6938 | + | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| ECKY1497_RS24790 (6944) | 6944..7782 | + | 839 | Protein_11 | Streptomycin 3''-adenylyltransferase | ARG |
| ECKY1497_RS24795 (7899) | 7899..8246 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| ECKY1497_RS24800 (8240) | 8240..9079 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| ECKY1497_RS24805 (9484) | 9484..11025 | + | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
| ECKY1497_RS24810 (11338) | 11338..11712 | + | 375 | Protein_15 | protein-disulfide reductase DsbD family protein | - |
| ECKY1497_RS24815 (11812) | 11812..12369 | + | 558 | Protein_16 | twin-arginine translocation (TAT) pathway signal sequence domain protein | - |
| ECKY1497_RS24820 (12380) | 12380..13018 | - | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| ECKY1497_RS24825 (13023) | 13023..13388 | - | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| ECKY1497_RS24830 (13392) | 13392..14204 | - | 813 | WP_023408309.1 | Metallo-beta-lactamase type 2 | ARG |
| ECKY1497_RS24835 (14305) | 14305..14598 | - | 294 | Protein_20 | IS30 family transposase ISAba125 | Transposase |
| ECKY1497_RS24840 (14763) | 14763..15467 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ECKY1497_RS24845 (15589) | 15589..16494 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| ECKY1497_RS24850 (16491) | 16491..17729 | + | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| ECKY1497_RS24855 (17729) | 17729..18313 | + | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| ECKY1497_RS24860 (18806) | 18806..19570 | - | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| ECKY1497_RS24865 (19872) | 19872..20429 | + | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| ECKY1497_RS24870 (20612) | 20612..21472 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| ECKY1497_RS24875 (22089) | 22089..23421 | + | 1333 | Protein_28 | group II intron reverse transcriptase/maturase | - |
| ECKY1497_RS24880 (23525) | 23525..23680 | + | 156 | Protein_29 | type II toxin-antitoxin system antitoxin YacA | - |
| ECKY1497_RS24885 (23680) | 23680..23958 | + | 279 | Protein_30 | type II toxin-antitoxin system toxin YacB | - |
| ECKY1497_RS24890 (24050) | 24050..24573 | - | 524 | Protein_31 | IS1 family transposase | - |
| ECKY1497_RS24895 (25100) | 25100..25549 | + | 450 | WP_029702172.1 | hypothetical protein | - |
| ECKY1497_RS24900 (25765) | 25765..26462 | + | 698 | WP_224053117.1 | IS1 family transposase IS1X2 | Transposase |
| ECKY1497_RS24905 (26502) | 26502..27242 | + | 741 | WP_029702141.1 | IS91 family transposase ISMno23 | Transposase |
| ECKY1497_RS24910 (27538) | 27538..27806 | + | 269 | Protein_35 | type II toxin-antitoxin system ParD family antitoxin | - |
| ECKY1497_RS24915 (27793) | 27793..28083 | + | 291 | Protein_36 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| ECKY1497_RS24920 (28150) | 28150..28332 | + | 183 | WP_042004909.1 | hypothetical protein | - |
| ECKY1497_RS24925 (28453) | 28453..29193 | + | 741 | WP_001586233.1 | tyrosine-type recombinase/integrase | - |
| ECKY1497_RS24930 (29516) | 29516..30505 | - | 990 | WP_123002471.1 | RepB family plasmid replication initiator protein | - |
| ECKY1497_RS24935 (31393) | 31393..31662 | + | 270 | WP_001275013.1 | DUF1778 domain-containing protein | Antitoxin Detail |
| ECKY1497_RS24940 (31666) | 31666..32196 | + | 531 | WP_000348883.1 | GNAT family N-acetyltransferase | Toxin Detail |
| ECKY1497_RS24945 (32197) | 32197..32414 | + | 218 | Protein_42 | transposase | - |
| ECKY1497_RS24950 (32470) | 32470..32786 | - | 317 | Protein_43 | type II toxin-antitoxin system VapC family toxin | - |
| ECKY1497_RS24955 (32783) | 32783..33013 | - | 231 | WP_001261274.1 | type II toxin-antitoxin system VapB family antitoxin | - |
| ECKY1497_RS24960 (32970) | 32970..33068 | + | 99 | Protein_45 | hypothetical protein | - |
| ECKY1497_RS24965 (33212) | 33212..35833 | - | 2622 | WP_001586230.1 | hypothetical protein | - |
| ECKY1497_RS24970 (36224) | 36224..36725 | + | 502 | Protein_47 | HEPN family nuclease | - |
| ECKY1497_RS24975 (36738) | 36738..37175 | + | 438 | WP_001403959.1 | hypothetical protein | - |
| ECKY1497_RS24980 (37121) | 37121..37510 | + | 390 | WP_001403960.1 | hypothetical protein | - |
| ECKY1497_RS24985 (37677) | 37677..38810 | + | 1134 | WP_000545985.1 | DUF3800 domain-containing protein | - |
| ECKY1497_RS24990 (38844) | 38844..39332 | - | 489 | WP_024187433.1 | hypothetical protein | - |
| ECKY1497_RS24995 (39643) | 39643..41208 | + | 1566 | WP_001586226.1 | AAA family ATPase | - |
| ECKY1497_RS25000 (41265) | 41265..42143 | - | 879 | WP_225522546.1 | hypothetical protein | - |
| ECKY1497_RS25005 (42136) | 42136..43224 | - | 1089 | Protein_54 | transcriptional regulator | - |
| ECKY1497_RS25010 (43517) | 43517..44449 | - | 933 | WP_000991831.1 | S-4TM family putative pore-forming effector | - |
| ECKY1497_RS25015 (44453) | 44453..45448 | - | 996 | WP_000246635.1 | hypothetical protein | - |
| ECKY1497_RS25020 (46126) | 46126..46476 | + | 351 | WP_039052452.1 | hypothetical protein | - |
| ECKY1497_RS25025 (46546) | 46546..47154 | + | 609 | WP_039052451.1 | hypothetical protein | - |
| ECKY1497_RS25030 (47222) | 47222..47982 | + | 761 | Protein_59 | tyrosine-type recombinase/integrase | - |
| ECKY1497_RS25035 (48120) | 48120..48395 | - | 276 | WP_000239529.1 | hypothetical protein | - |
| ECKY1497_RS25040 (48389) | 48389..49033 | - | 645 | WP_000633913.1 | division plane positioning ATPase MipZ | - |
| ECKY1497_RS25045 (49262) | 49262..50233 | + | 972 | WP_039052450.1 | plasmid segregation protein ParM | - |
| ECKY1497_RS25050 (50238) | 50238..50630 | + | 393 | WP_039052449.1 | plasmid partitioning/stability family protein | - |
| ECKY1497_RS25055 (50635) | 50635..51725 | - | 1091 | Protein_64 | translesion error-prone DNA polymerase V subunit UmuC | - |
| ECKY1497_RS25060 (52139) | 52139..53119 | - | 981 | WP_039052448.1 | IS5 family transposase ISKpn26 | Transposase |
| ECKY1497_RS25065 (53462) | 53462..55726 | - | 2265 | WP_039052447.1 | UvrD-helicase domain-containing protein | - |
| ECKY1497_RS25070 (55728) | 55728..56516 | - | 789 | WP_224053116.1 | hypothetical protein | - |
| ECKY1497_RS25080 (58629) | 58629..59846 | + | 1218 | WP_061856962.1 | IS4 family transposase IS10R | Transposase |
| ECKY1497_RS25085 (59856) | 59856..60272 | - | 417 | WP_000275180.1 | Transposon Tn10 TetD protein | VF |
| ECKY1497_RS25090 (60360) | 60360..60953 | + | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| ECKY1497_RS25095 (61066) | 61066..62271 | - | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| ECKY1497_RS25100 (62353) | 62353..62976 | + | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| ECKY1497_RS25105 (62954) | 62954..63640 | - | 687 | WP_001284954.1 | winged helix-turn-helix domain-containing protein | - |
| ECKY1497_RS25110 (63648) | 63648..64034 | - | 387 | WP_000460651.1 | hypothetical protein | - |
| ECKY1497_RS25115 (64027) | 64027..64347 | - | 321 | WP_000562370.1 | antibiotic biosynthesis monooxygenase | - |
| ECKY1497_RS25120 (64791) | 64791..65024 | + | 234 | Protein_77 | sodium/glutamate symporter | - |
| ECKY1497_RS25130 (65856) | 65856..66509 | - | 654 | WP_039052615.1 | DUF5710 domain-containing protein | - |
| ECKY1497_RS25135 (66547) | 66547..66894 | - | 348 | WP_077877391.1 | hypothetical protein | - |
| ECKY1497_RS25140 (67080) | 67080..67529 | + | 450 | Protein_81 | hypothetical protein | - |
| ECKY1497_RS25145 (67945) | 67945..68370 | + | 426 | WP_061856959.1 | antirestriction protein | - |
| ECKY1497_RS25150 (68419) | 68419..68610 | + | 192 | WP_001027495.1 | hypothetical protein | - |
| ECKY1497_RS25155 (68752) | 68752..69048 | - | 297 | Protein_84 | hypothetical protein | - |
| ECKY1497_RS25160 (69563) | 69563..69792 | + | 230 | Protein_85 | hypothetical protein | - |
| ECKY1497_RS25165 (69844) | 69844..71205 | + | 1362 | WP_039052595.1 | DUF3560 domain-containing protein | - |
| ECKY1497_RS25170 (71253) | 71253..71816 | + | 564 | WP_001377760.1 | class I SAM-dependent methyltransferase | - |
| ECKY1497_RS25175 (71904) | 71904..72333 | - | 430 | Protein_88 | hypothetical protein | - |
| ECKY1497_RS25180 (72516) | 72516..73436 | + | 921 | WP_039052596.1 | aminoimidazole riboside kinase | - |
| ECKY1497_RS25185 (73604) | 73604..75121 | + | 1518 | WP_039052597.1 | carbohydrate porin | - |
| ECKY1497_RS25190 (75182) | 75182..76552 | + | 1371 | WP_000344915.1 | sucrose-specific PTS transporter subunit IIBC | - |
| ECKY1497_RS25195 (76552) | 76552..77961 | + | 1410 | WP_039052598.1 | sucrose-6-phosphate hydrolase | - |
| ECKY1497_RS25200 (77987) | 77987..78994 | + | 1008 | WP_001232702.1 | LacI family DNA-binding transcriptional regulator | - |
| ECKY1497_RS25205 (79458) | 79458..80075 | - | 618 | Protein_94 | ISL3 family transposase ISEc38 | Transposase |
| ECKY1497_RS25210 (80248) | 80248..80945 | + | 698 | WP_103215986.1 | IS1 family transposase IS1G | Transposase |
| ECKY1497_RS25215 (81025) | 81025..81156 | - | 132 | Protein_96 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| ECKY1497_RS25220 (81147) | 81147..81475 | - | 329 | Protein_97 | hypothetical protein | - |
| ECKY1497_RS25225 (81776) | 81776..82063 | + | 288 | WP_061856957.1 | hypothetical protein | - |
| ECKY1497_RS25230 (82182) | 82182..83003 | + | 822 | WP_061856956.1 | DUF932 domain-containing protein | - |
| ECKY1497_RS25235 (83299) | 83299..83901 | - | 603 | WP_077878371.1 | hypothetical protein | VF |
| ECKY1497_RS25240 (84221) | 84221..84604 | + | 384 | WP_061856954.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| ECKY1497_RS25245 (84791) | 84791..85480 | + | 690 | WP_061856953.1 | conjugal transfer transcriptional regulator TraJ | - |
| ECKY1497_RS25250 (85573) | 85573..85974 | + | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| ECKY1497_RS25255 (86007) | 86007..86369 | + | 363 | WP_039052460.1 | type IV conjugative transfer system pilin TraA | - |
| ECKY1497_RS25260 (86374) | 86374..86685 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| ECKY1497_RS25265 (86707) | 86707..87273 | + | 567 | WP_039052461.1 | type IV conjugative transfer system protein TraE | - |
| ECKY1497_RS25270 (87260) | 87260..87988 | + | 729 | WP_039052462.1 | type-F conjugative transfer system secretin TraK | - |
| ECKY1497_RS25275 (87988) | 87988..89439 | + | 1452 | WP_039052463.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| ECKY1497_RS25280 (89429) | 89429..89989 | + | 561 | WP_039052464.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| ECKY1497_RS25285 (89976) | 89976..90296 | + | 321 | WP_001057302.1 | conjugal transfer protein TrbD | - |
| ECKY1497_RS25290 (90289) | 90289..90540 | + | 252 | WP_039052465.1 | conjugal transfer protein TrbG | - |
| ECKY1497_RS25295 (90537) | 90537..91052 | + | 516 | WP_039052466.1 | type IV conjugative transfer system lipoprotein TraV | - |
| ECKY1497_RS25300 (91187) | 91187..91408 | + | 222 | WP_001278685.1 | conjugal transfer protein TraR | - |
| ECKY1497_RS25305 (91568) | 91568..94195 | + | 2628 | WP_001064265.1 | type IV secretion system protein TraC | - |
| ECKY1497_RS25310 (94192) | 94192..94578 | + | 387 | WP_000099693.1 | type-F conjugative transfer system protein TrbI | - |
| ECKY1497_RS25315 (94575) | 94575..95207 | + | 633 | WP_039052467.1 | type-F conjugative transfer system protein TraW | - |
| ECKY1497_RS25320 (95204) | 95204..96196 | + | 993 | WP_000830835.1 | conjugal transfer pilus assembly protein TraU | - |
| ECKY1497_RS25325 (96205) | 96205..96843 | + | 639 | WP_039052468.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| ECKY1497_RS25330 (96840) | 96840..97220 | + | 381 | WP_039052469.1 | hypothetical protein | - |
| ECKY1497_RS25335 (97456) | 97456..99318 | + | 1863 | WP_224053115.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| ECKY1497_RS25340 (99345) | 99345..99602 | + | 258 | WP_039023152.1 | conjugal transfer protein TrbE | - |
| ECKY1497_RS25345 (99595) | 99595..100338 | + | 744 | WP_001030376.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| ECKY1497_RS25350 (100354) | 100354..100701 | + | 348 | WP_001287894.1 | conjugal transfer protein TrbA | - |
| ECKY1497_RS25355 (100820) | 100820..101104 | + | 285 | WP_000624110.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| ECKY1497_RS25360 (101091) | 101091..101636 | + | 546 | WP_039052470.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| ECKY1497_RS25365 (101566) | 101566..101928 | + | 363 | WP_071550055.1 | P-type conjugative transfer protein TrbJ | - |
| ECKY1497_RS25370 (101928) | 101928..103301 | + | 1374 | WP_039023150.1 | conjugal transfer pilus assembly protein TraH | - |
| ECKY1497_RS25375 (103298) | 103298..106117 | + | 2820 | WP_039023149.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| ECKY1497_RS25380 (106136) | 106136..106633 | + | 498 | WP_000605862.1 | entry exclusion protein | - |
| ECKY1497_RS25385 (106665) | 106665..107396 | + | 732 | WP_000850422.1 | conjugal transfer complement resistance protein TraT | - |
| ECKY1497_RS25390 (107649) | 107649..109838 | + | 2190 | WP_073961454.1 | type IV conjugative transfer system coupling protein TraD | - |
| ECKY1497_RS25395 (109847) | 109847..110245 | - | 399 | WP_039023147.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| ECKY1497_RS25400 (110245) | 110245..110472 | - | 228 | WP_039023146.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| ECKY1497_RS25405 (110554) | 110554..115824 | + | 5271 | WP_039052472.1 | Multifunctional conjugation protein TraI | Relaxase |
| ECKY1497_RS25410 (116100) | 116100..117641 | + | 1542 | WP_002431311.1 | IS21 family transposase ISEc12 | Transposase |
| ECKY1497_RS25415 (117656) | 117656..118402 | + | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| ECKY1497_RS25420 (118430) | 118430..119176 | + | 747 | WP_052273601.1 | conjugal transfer pilus acetylase TraX | - |
| ECKY1497_RS25425 (119231) | 119231..119791 | + | 561 | WP_001567328.1 | fertility inhibition protein FinO | - |
| ECKY1497_RS25430 (119922) | 119922..120131 | + | 210 | WP_039023209.1 | hypothetical protein | - |
| ECKY1497_RS25435 (120543) | 120543..121169 | + | 627 | WP_029702149.1 | NYN domain-containing protein | - |
| ECKY1497_RS25440 (121321) | 121321..121890 | + | 570 | WP_029702150.1 | DUF2726 domain-containing protein | - |
| ECKY1497_RS25445 (122103) | 122103..122531 | + | 429 | WP_029702151.1 | hypothetical protein | - |
| - (122670) | 122670..122731 | - | 62 | NuclAT_0 | - | Antitoxin Detail |
| - (122670) | 122670..122731 | - | 62 | NuclAT_0 | - | Antitoxin Detail |
| - (122670) | 122670..122731 | - | 62 | NuclAT_0 | - | Antitoxin Detail |
| - (122670) | 122670..122731 | - | 62 | NuclAT_0 | - | Antitoxin Detail |
| ECKY1497_RS25450 (122775) | 122775..122924 | + | 150 | WP_001367749.1 | Hok/Gef family protein | Toxin Detail |
| ECKY1497_RS25455 (123208) | 123208..123465 | + | 258 | WP_000083833.1 | replication regulatory protein RepA | - |
| ECKY1497_RS25460 (123570) | 123570..123755 | + | 186 | WP_077818652.1 | protein CopA/IncA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|