MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 145853 bp
Accession: NZ_AP019306 Location: 659378..805230 Organism: Staphylococcus aureus strain TUM9463 Replicon: chromosome
Accession: NZ_AP019306 Location: 659378..805230 Organism: Staphylococcus aureus strain TUM9463 Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EKM74_RS03610 () | 655339..656796 | - | 1458 | WP_000027919.1 | Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA | - |
| EKM74_RS03615 () | 656798..657100 | - | 303 | WP_000170162.1 | Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC | - |
| EKM74_RS03620 () | 657467..659005 | + | 1539 | WP_000957020.1 | sodium/proline symporter PutP | - |
| EKM74_RS03625 () | 659094..660293 | - | 1200 | WP_000831700.1 | CamS family sex pheromone protein | - |
| EKM74_RS03630 () | 660306..662309 | - | 2004 | WP_000774556.1 | NAD-dependent DNA ligase LigA | - |
| EKM74_RS03635 () | 662313..664505 | - | 2193 | WP_000992924.1 | DNA helicase PcrA | - |
| EKM74_RS03640 () | 664502..665194 | - | 693 | WP_000272056.1 | heptaprenylglyceryl phosphate synthase | - |
| EKM74_RS03645 () | 665366..665668 | - | 303 | WP_001165363.1 | hypothetical protein | - |
| EKM74_RS03650 () | 665777..667072 | - | 1296 | WP_000572878.1 | adenylosuccinate lyase | - |
| EKM74_RS03660 () | 667920..669092 | - | 1173 | WP_000195429.1 | IS256 family transposase IS256 | Transposase |
| EKM74_RS03665 () | 669264..670430 | + | 1167 | WP_000827746.1 | Staphopain A | VF |
| EKM74_RS03670 () | 670461..670787 | + | 327 | WP_000434933.1 | staphostatin A | - |
| EKM74_RS03675 () | 671079..671252 | - | 174 | WP_000669862.1 | NETI motif-containing protein | - |
| EKM74_RS03680 () | 671233..671835 | - | 603 | WP_000011542.1 | DUF2179 domain-containing protein | - |
| EKM74_RS03685 () | 672106..672927 | - | 822 | WP_000040866.1 | ammonia-dependent NAD(+) synthetase | - |
| EKM74_RS03690 () | 672920..674389 | - | 1470 | WP_000284436.1 | nicotinate phosphoribosyltransferase | - |
| EKM74_RS03695 () | 674573..675655 | + | 1083 | WP_125571281.1 | nitric oxide synthase oxygenase | - |
| EKM74_RS03700 () | 675675..676469 | + | 795 | WP_001177828.1 | prephenate dehydratase | - |
| EKM74_RS03705 () | 676541..676648 | + | 108 | WP_001802312.1 | hypothetical protein | - |
| EKM74_RS03710 () | 676659..678221 | - | 1563 | WP_000323161.1 | SLC13 family permease | - |
| EKM74_RS03715 () | 678426..679523 | - | 1098 | WP_000275727.1 | pectate lyase | - |
| EKM74_RS03720 () | 679892..680452 | + | 561 | WP_000149686.1 | Peroxyureidoacrylate/ureidoacrylate amidohydrolase RutB | VF |
| EKM74_RS03725 () | 680505..681434 | + | 930 | WP_001140871.1 | manganese-dependent inorganic pyrophosphatase | - |
| EKM74_RS03730 () | 681627..681800 | - | 174 | WP_001792184.1 | hypothetical protein | - |
| EKM74_RS03735 () | 681852..683231 | + | 1380 | WP_001021210.1 | aldehyde dehydrogenase | - |
| EKM74_RS03740 () | 683351..684379 | - | 1029 | WP_000181315.1 | lactonase family protein | - |
| EKM74_RS03745 () | 684649..685050 | + | 402 | WP_000205106.1 | YolD-like family protein | - |
| EKM74_RS03750 () | 685068..685276 | - | 209 | Protein_684 | transposase | - |
| EKM74_RS03755 () | 685623..685796 | - | 174 | WP_000267034.1 | hypothetical protein | - |
| EKM74_RS03760 () | 686247..687287 | + | 1041 | WP_001188043.1 | linear amide C-N hydrolase | - |
| EKM74_RS03765 () | 687344..688186 | - | 843 | WP_000713072.1 | DUF4097 family beta strand repeat protein | - |
| EKM74_RS03770 () | 688183..688740 | - | 558 | WP_001033971.1 | DUF1700 domain-containing protein | - |
| EKM74_RS03775 () | 688800..689324 | - | 525 | WP_000966288.1 | membrane protein | - |
| EKM74_RS03780 () | 689445..690008 | + | 564 | WP_000182842.1 | thioredoxin family protein | - |
| EKM74_RS03785 () | 690074..690814 | - | 741 | WP_001221651.1 | phenol-soluble modulin export ABC transporter permease subunit PmtD | - |
| EKM74_RS03790 () | 690814..691686 | - | 873 | WP_000763043.1 | phenol-soluble modulin export ABC transporter ATP-binding protein PmtC | - |
| EKM74_RS03795 () | 691683..692363 | - | 681 | WP_000645727.1 | phenol-soluble modulin export ABC transporter permease subunit PmtB | - |
| EKM74_RS03800 () | 692364..693260 | - | 897 | WP_000991306.1 | ABC transporter ATP-binding protein NatA | VF |
| EKM74_RS03805 () | 693257..693637 | - | 381 | WP_000691584.1 | GntR family transcriptional regulator | - |
| EKM74_RS03810 () | 693895..694071 | - | 177 | WP_000681968.1 | hypothetical protein | - |
| EKM74_RS03815 () | 694314..694412 | - | 99 | WP_000990056.1 | hypothetical protein | - |
| EKM74_RS03820 () | 694612..695898 | + | 1287 | WP_001068542.1 | aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme | - |
| EKM74_RS03830 () | 696094..697266 | - | 1173 | WP_000195429.1 | IS256 family transposase IS256 | Transposase |
| EKM74_RS03840 () | 697509..697799 | - | 291 | WP_000671712.1 | Protein map | VF |
| EKM74_RS03845 () | 697814..699244 | - | 1431 | WP_001557458.1 | Protein map | VF |
| EKM74_RS03855 () | 700224..701183 | - | 960 | WP_002303350.1 | IS30 family transposase IS1062 | Transposase |
| EKM74_RS03860 () | 701306..701446 | + | 141 | WP_048516856.1 | hypothetical protein | - |
| EKM74_RS03870 () | 701761..702021 | + | 261 | WP_001791826.1 | hypothetical protein | - |
| EKM74_RS03875 () | 702074..702424 | - | 351 | WP_000702262.1 | Staphylococcal complement inhibitor | VF |
| EKM74_RS03880 () | 703107..703556 | + | 450 | WP_000727645.1 | Chemotaxis inhibitory protein | VF |
| EKM74_RS03885 () | 703651..703985 | - | 335 | Protein_707 | SH3 domain-containing protein | - |
| EKM74_RS03900 () | 704632..705123 | - | 492 | WP_000920042.1 | Staphylokinase | VF |
| EKM74_RS03905 () | 705314..706069 | - | 756 | WP_000861026.1 | CHAP domain-containing protein | - |
| EKM74_RS03910 () | 706081..706335 | - | 255 | WP_000611512.1 | phage holin | - |
| EKM74_RS03915 () | 706387..706494 | + | 108 | WP_031762631.1 | hypothetical protein | - |
| - () | 706416..706555 | + | 140 | NuclAT_0 | - | Antitoxin Detail |
| - () | 706416..706555 | + | 140 | NuclAT_0 | - | Antitoxin Detail |
| - () | 706416..706555 | + | 140 | NuclAT_0 | - | Antitoxin Detail |
| - () | 706416..706555 | + | 140 | NuclAT_0 | - | Antitoxin Detail |
| EKM74_RS03920 () | 706547..706723 | - | 177 | WP_011447039.1 | putative holin-like toxin | Toxin Detail |
| EKM74_RS03925 () | 706926..707699 | - | 774 | WP_025174055.1 | Enterotoxin type E | VF |
| EKM74_RS03930 () | 707921..709093 | + | 1173 | WP_000195429.1 | IS256 family transposase IS256 | Transposase |
| EKM74_RS03935 () | 709223..710662 | - | 1440 | WP_001028144.1 | Bifunctional AAC/APH | ARG |
| EKM74_RS03940 () | 710663..711055 | - | 393 | WP_000393259.1 | GNAT family N-acetyltransferase | - |
| EKM74_RS03945 () | 711112..712284 | - | 1173 | WP_000195429.1 | IS256 family transposase IS256 | Transposase |
| EKM74_RS03955 () | 712695..713069 | - | 375 | WP_000340977.1 | hypothetical protein | - |
| EKM74_RS03960 () | 713125..713412 | - | 288 | WP_001262621.1 | hypothetical protein | - |
| EKM74_RS03965 () | 713458..713610 | - | 153 | WP_001000058.1 | hypothetical protein | - |
| EKM74_RS03970 () | 713603..717385 | - | 3783 | WP_000582152.1 | hypothetical protein | - |
| EKM74_RS03975 () | 717401..718885 | - | 1485 | WP_000567396.1 | phage tail family protein | - |
| EKM74_RS03980 () | 718882..723411 | - | 4530 | WP_084943896.1 | phage tail tape measure protein | - |
| EKM74_RS03985 () | 723656..724006 | - | 351 | WP_001096355.1 | hypothetical protein | - |
| EKM74_RS03990 () | 724056..724280 | - | 225 | WP_071621395.1 | Ig-like domain-containing protein | - |
| EKM74_RS03995 () | 724322..724966 | - | 645 | WP_000268740.1 | phage tail protein | - |
| EKM74_RS04000 () | 724967..725374 | - | 408 | WP_000565498.1 | hypothetical protein | - |
| EKM74_RS04005 () | 725371..725775 | - | 405 | WP_000114226.1 | HK97 gp10 family phage protein | - |
| EKM74_RS04010 () | 725772..726134 | - | 363 | WP_000755150.1 | head-tail adaptor protein | - |
| EKM74_RS04015 () | 726118..726402 | - | 285 | WP_000150936.1 | phage head-tail adapter protein | - |
| EKM74_RS04020 () | 726392..726676 | - | 285 | WP_000238236.1 | hypothetical protein | - |
| EKM74_RS04025 () | 726696..727841 | - | 1146 | WP_000154559.1 | phage major capsid protein | - |
| EKM74_RS04030 () | 727865..728602 | - | 738 | WP_000642728.1 | Clp protease ClpP | - |
| EKM74_RS04035 () | 728586..729773 | - | 1188 | WP_000025274.1 | phage portal protein | - |
| EKM74_RS04040 () | 729789..731450 | - | 1662 | WP_000625088.1 | terminase large subunit | - |
| EKM74_RS04045 () | 731447..731791 | - | 345 | WP_000402904.1 | hypothetical protein | - |
| EKM74_RS04050 () | 731922..732221 | - | 300 | WP_000988332.1 | HNH endonuclease | - |
| EKM74_RS04055 () | 732453..732869 | - | 417 | WP_000590122.1 | hypothetical protein | - |
| EKM74_RS04060 () | 732897..733097 | - | 201 | WP_001557462.1 | DUF1514 family protein | - |
| EKM74_RS04065 () | 733097..733246 | - | 150 | WP_000595265.1 | transcriptional activator RinB | - |
| EKM74_RS04070 () | 733243..733449 | - | 207 | WP_000195784.1 | DUF1381 domain-containing protein | - |
| EKM74_RS04075 () | 733446..733691 | - | 246 | WP_001282077.1 | hypothetical protein | - |
| EKM74_RS04080 () | 733728..734264 | - | 537 | WP_000185693.1 | dUTPase | - |
| EKM74_RS04085 () | 734261..734506 | - | 246 | WP_001065108.1 | DUF1024 family protein | - |
| EKM74_RS04090 () | 734521..734769 | - | 249 | WP_000178987.1 | hypothetical protein | - |
| EKM74_RS04095 () | 734766..735023 | - | 258 | WP_000111491.1 | DUF3310 domain-containing protein | - |
| EKM74_RS04100 () | 735023..735394 | - | 372 | WP_000101279.1 | hypothetical protein | - |
| EKM74_RS04105 () | 735407..735811 | - | 405 | WP_000401969.1 | RusA family crossover junction endodeoxyribonuclease | - |
| EKM74_RS04110 () | 735820..736038 | - | 219 | WP_000338528.1 | hypothetical protein | - |
| EKM74_RS04115 () | 736045..736938 | - | 894 | WP_000148333.1 | DnaD domain-containing protein | - |
| EKM74_RS04120 () | 736968..737438 | - | 471 | WP_000934759.1 | single-stranded DNA-binding protein | - |
| EKM74_RS04125 () | 737439..738056 | - | 618 | WP_064135358.1 | MBL fold metallo-hydrolase | - |
| EKM74_RS04130 () | 738137..739057 | - | 921 | WP_042109507.1 | recombinase RecT | - |
| EKM74_RS04135 () | 739059..741002 | - | 1944 | WP_001620112.1 | AAA family ATPase | - |
| EKM74_RS04140 () | 741011..741274 | - | 264 | WP_001205732.1 | hypothetical protein | - |
| EKM74_RS04145 () | 741283..741543 | - | 261 | WP_000291510.1 | DUF1108 family protein | - |
| EKM74_RS04150 () | 741548..741850 | - | 303 | WP_042109511.1 | DUF2482 family protein | - |
| EKM74_RS04155 () | 741945..742106 | - | 162 | WP_000048129.1 | DUF1270 family protein | - |
| EKM74_RS04160 () | 742103..742426 | - | 324 | WP_001120201.1 | DUF771 domain-containing protein | - |
| EKM74_RS04165 () | 742481..742861 | + | 381 | WP_000762521.1 | DUF2513 domain-containing protein | - |
| EKM74_RS04170 () | 742848..743045 | - | 198 | WP_001148856.1 | hypothetical protein | - |
| EKM74_RS04175 () | 743061..743813 | - | 753 | WP_001148605.1 | phage antirepressor KilAC domain-containing protein | - |
| EKM74_RS04180 () | 743864..744193 | + | 330 | WP_000128909.1 | hypothetical protein | - |
| EKM74_RS04185 () | 744182..744397 | - | 216 | WP_001025404.1 | DUF2829 domain-containing protein | - |
| EKM74_RS04190 () | 744413..744676 | - | 264 | WP_000854072.1 | helix-turn-helix domain-containing protein | - |
| EKM74_RS04195 () | 744673..744847 | - | 175 | Protein_766 | transcriptional regulator | - |
| EKM74_RS04200 () | 744810..745523 | + | 714 | WP_001031454.1 | XRE family transcriptional regulator | - |
| EKM74_RS04205 () | 745539..746471 | + | 933 | WP_000759682.1 | ATP-dependent helicase | - |
| EKM74_RS04210 () | 746477..746818 | + | 342 | WP_000591749.1 | hypothetical protein | - |
| EKM74_RS04215 () | 747022..747204 | + | 183 | WP_000694772.1 | hypothetical protein | - |
| EKM74_RS04220 () | 747304..748287 | + | 984 | WP_001558608.1 | Putative teichuronic acid biosynthesis glycosyltransferase TuaG | VF |
| EKM74_RS04225 () | 748298..748540 | + | 243 | WP_000427213.1 | hypothetical protein | - |
| EKM74_RS04230 () | 748603..749640 | + | 1038 | WP_000857180.1 | Tyrosine recombinase XerC ; Integrase | Integrase |
| EKM74_RS04235 () | 749691..750521 | + | 831 | Protein_774 | Phospholipase C | VF |
| EKM74_RS04240 () | 750759..751775 | - | 1017 | WP_000595392.1 | putative leukocidin-like protein 1 | VF |
| EKM74_RS04245 () | 751797..752852 | - | 1056 | WP_000791411.1 | putative leukocidin-like protein 2 | VF |
| EKM74_RS04250 () | 753288..754511 | + | 1224 | WP_000206625.1 | ArgE/DapE family deacylase | - |
| EKM74_RS04255 () | 754955..756262 | + | 1308 | WP_001045079.1 | TrkH family potassium uptake protein | - |
| EKM74_RS04270 () | 757437..758609 | + | 1173 | WP_000195429.1 | IS256 family transposase IS256 | Transposase |
| EKM74_RS04275 () | 759231..759791 | + | 561 | WP_001035616.1 | DUF4888 domain-containing protein | - |
| EKM74_RS04280 () | 760670..761374 | + | 705 | WP_001035599.1 | Toxic shock syndrome toxin-1 | VF |
| EKM74_RS04285 () | 761529..762098 | - | 570 | WP_001293088.1 | terminase small subunit | - |
| EKM74_RS04290 () | 762095..762436 | - | 342 | WP_000358774.1 | hypothetical protein | - |
| EKM74_RS04295 () | 762439..762966 | - | 528 | WP_000771368.1 | spore coat protein | - |
| EKM74_RS04300 () | 763017..763235 | - | 219 | WP_000448770.1 | capsid morphogenesis B protein | - |
| EKM74_RS04305 () | 763253..763831 | - | 579 | WP_125571283.1 | pathogenicity island protein | - |
| EKM74_RS04310 () | 763843..764184 | - | 342 | WP_001190615.1 | hypothetical protein | - |
| EKM74_RS04315 () | 764634..765275 | - | 642 | WP_063663566.1 | pathogenicity island protein | - |
| EKM74_RS04320 () | 765272..765652 | - | 381 | WP_000356942.1 | hypothetical protein | - |
| EKM74_RS04325 () | 765962..767671 | - | 1710 | WP_000447473.1 | DUF927 domain-containing protein | - |
| EKM74_RS04330 () | 767685..768554 | - | 870 | WP_001002689.1 | primase alpha helix C-terminal domain-containing protein | - |
| EKM74_RS04335 () | 768619..768945 | - | 327 | WP_001078344.1 | DUF1474 family protein | Toxin Detail |
| EKM74_RS04340 () | 768948..769097 | - | 150 | WP_025175789.1 | hypothetical protein | Antitoxin Detail |
| EKM74_RS04345 () | 769150..769296 | - | 147 | WP_000784885.1 | hypothetical protein | - |
| EKM74_RS04350 () | 769293..769610 | - | 318 | WP_000481967.1 | helix-turn-helix domain-containing protein | - |
| EKM74_RS04355 () | 769615..769833 | - | 219 | WP_000153640.1 | helix-turn-helix transcriptional regulator | - |
| EKM74_RS04360 () | 770006..770680 | + | 675 | WP_000620857.1 | helix-turn-helix transcriptional regulator | - |
| EKM74_RS04365 () | 770694..771866 | + | 1173 | WP_000179343.1 | Transposase from transposon Tn916 ; Integrase | Integrase |
| EKM74_RS04370 () | 771935..773551 | - | 1617 | WP_000240642.1 | 60 kDa chaperonin | VF |
| EKM74_RS04375 () | 773627..773911 | - | 285 | WP_000917289.1 | co-chaperone GroES | - |
| EKM74_RS04380 () | 774086..774829 | + | 744 | WP_000197635.1 | CPBP family intramembrane metalloprotease | - |
| EKM74_RS04385 () | 774854..776101 | - | 1248 | WP_000120296.1 | hypothetical protein | VF |
| EKM74_RS04390 () | 776298..776924 | + | 627 | WP_000522381.1 | nitroreductase family protein | - |
| EKM74_RS04395 () | 777285..778070 | + | 786 | WP_000867951.1 | carbon-nitrogen family hydrolase | - |
| EKM74_RS04400 () | 778670..778804 | - | 135 | WP_001549197.1 | Delta-hemolysin | VF |
| EKM74_RS04405 () | 779040..779603 | + | 564 | WP_001105696.1 | accessory gene regulator ArgB-like protein | - |
| EKM74_RS04410 () | 779606..779749 | + | 144 | WP_001094921.1 | cyclic lactone autoinducer peptide | - |
| EKM74_RS04415 () | 779779..781062 | + | 1284 | WP_042109531.1 | GHKL domain-containing protein | - |
| EKM74_RS04420 () | 781242..782561 | - | 1320 | WP_001557163.1 | ISL3 family transposase IS1181 | Transposase |
| EKM74_RS04430 () | 782682..783317 | + | 636 | Protein_810 | response regulator transcription factor | - |
| EKM74_RS04435 () | 783389..783498 | + | 110 | Protein_811 | hypothetical protein | - |
| EKM74_RS04440 () | 783686..784645 | - | 960 | WP_001253312.1 | carbohydrate kinase | - |
| EKM74_RS04445 () | 784642..786126 | - | 1485 | WP_000141432.1 | glycoside hydrolase family 32 protein | - |
| EKM74_RS04450 () | 786275..787225 | - | 951 | WP_000790331.1 | LacI family DNA-binding transcriptional regulator | - |
| EKM74_RS04455 () | 787408..788658 | - | 1251 | WP_001052270.1 | ammonium transporter | - |
| EKM74_RS04460 () | 788866..789090 | - | 225 | WP_000581076.1 | sulfurtransferase TusA family protein | - |
| EKM74_RS04465 () | 789150..790229 | - | 1080 | WP_000266884.1 | YeeE/YedE family protein | - |
| EKM74_RS04470 () | 790533..791168 | - | 636 | WP_001283612.1 | redox-sensing transcriptional repressor Rex | - |
| EKM74_RS04475 () | 791421..793349 | + | 1929 | WP_000602057.1 | ABC-F type ribosomal protection protein | - |
| EKM74_RS04480 () | 793494..793622 | - | 129 | WP_001792272.1 | hypothetical protein | - |
| EKM74_RS04485 () | 793711..795321 | + | 1611 | WP_000106332.1 | MutS family DNA mismatch repair protein | - |
| EKM74_RS04490 () | 795636..796661 | - | 1026 | WP_000159041.1 | tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD | - |
| EKM74_RS04495 () | 796654..797118 | - | 465 | WP_000372758.1 | N-alpha-acetyltransferase RimI | VF |
| EKM74_RS04500 () | 797091..797753 | - | 663 | WP_001086737.1 | tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB | - |
| EKM74_RS04505 () | 797734..798195 | - | 462 | WP_000590805.1 | tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE | - |
| EKM74_RS04510 () | 798233..798388 | + | 156 | WP_001789600.1 | hypothetical protein | - |
| EKM74_RS04515 () | 798706..800394 | + | 1689 | WP_001255780.1 | dihydroxy-acid dehydratase | - |
| EKM74_RS04520 () | 800422..802191 | + | 1770 | WP_000047811.1 | biosynthetic-type acetolactate synthase large subunit | - |
| EKM74_RS04525 () | 802191..802445 | + | 255 | WP_000196911.1 | ACT domain-containing protein | - |
| EKM74_RS04530 () | 802567..803586 | + | 1020 | WP_072399972.1 | ketol-acid reductoisomerase | - |
| EKM74_RS04535 () | 803616..805145 | + | 1530 | WP_000094583.1 | 2-isopropylmalate synthase | - |
| EKM74_RS04540 () | 805148..806194 | + | 1047 | WP_000221945.1 | 3-isopropylmalate dehydrogenase | - |
| EKM74_RS04545 () | 806208..807578 | + | 1371 | WP_000531823.1 | 3-isopropylmalate dehydratase large subunit | - |
| EKM74_RS04550 () | 807579..808151 | + | 573 | WP_000718953.1 | 3-isopropylmalate dehydratase small subunit | - |
| EKM74_RS04555 () | 808166..809434 | + | 1269 | WP_000216856.1 | threonine ammonia-lyase IlvA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|