MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 182276 bp
Accession: NC_017846 Location: 1948724..2130999 Organism: Aggregatibacter actinomycetemcomitans D7S-1 Replicon: chromosome
Accession: NC_017846 Location: 1948724..2130999 Organism: Aggregatibacter actinomycetemcomitans D7S-1 Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| D7S_RS09750 () | 1943991..1945181 | + | 1191 | WP_005541118.1 | cystathionine beta-lyase | - |
| D7S_RS09755 () | 1945395..1946447 | + | 1053 | WP_005541120.1 | porin | - |
| D7S_RS09760 () | 1946592..1946849 | + | 258 | WP_005541121.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| D7S_RS09765 () | 1946849..1947196 | + | 348 | WP_005541123.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| D7S_RS09770 () | 1947274..1948401 | - | 1128 | WP_005541126.1 | molecular chaperone DnaJ | - |
| D7S_RS09775 () | 1948840..1950741 | - | 1902 | WP_005551736.1 | molecular chaperone DnaK | - |
| D7S_RS09780 () | 1951030..1952464 | + | 1435 | Protein_1856 | YdgA family protein | - |
| D7S_RS09785 () | 1952551..1953197 | - | 647 | Protein_1857 | IS1595 family transposase ISHpa1 | Transposase |
| D7S_RS09790 () | 1953505..1954239 | + | 735 | WP_005553155.1 | molybdate ABC transporter substrate-binding protein | - |
| D7S_RS09795 () | 1954214..1955011 | + | 798 | WP_005543861.1 | ABC transporter permease | - |
| D7S_RS09800 () | 1955014..1955628 | + | 615 | WP_005551731.1 | Sulfate/thiosulfate import ATP-binding protein CysA | VF |
| D7S_RS09805 () | 1955625..1956485 | + | 861 | WP_005543858.1 | ModD protein | - |
| D7S_RS09810 () | 1956782..1958230 | + | 1449 | WP_005553160.1 | metalloprotease TldD | - |
| D7S_RS09815 () | 1958296..1964067 | + | 5772 | WP_005543854.1 | alpha-2-macroglobulin | - |
| D7S_RS09820 () | 1964234..1965250 | + | 1017 | WP_005543852.1 | YeiH family putative sulfate export transporter | - |
| D7S_RS09825 () | 1965370..1967727 | + | 2358 | WP_005553165.1 | penicillin-binding protein 1C | - |
| D7S_RS11915 () | 1967892..1968062 | + | 171 | WP_014702274.1 | hypothetical protein | VF |
| D7S_RS09830 () | 1968059..1969968 | + | 1910 | Protein_1867 | Actin cross-linking toxin VgrG1 | VF |
| D7S_RS12065 () | 1969984..1971106 | + | 1123 | Protein_1868 | glycoside hydrolase family 19 | - |
| D7S_RS09845 () | 1971143..1971793 | + | 651 | WP_014702538.1 | hypothetical protein | - |
| D7S_RS09850 () | 1971968..1972150 | + | 183 | WP_005550326.1 | hypothetical protein | - |
| D7S_RS09855 () | 1972426..1973001 | + | 576 | WP_005553102.1 | hypothetical protein | - |
| D7S_RS09865 () | 1973569..1973838 | + | 270 | WP_005540356.1 | PTS sugar transporter subunit IIB | - |
| D7S_RS09870 () | 1973855..1975210 | + | 1356 | WP_005540354.1 | PTS ascorbate transporter subunit IIC | - |
| D7S_RS09875 () | 1975220..1976044 | + | 825 | WP_005540352.1 | transketolase | - |
| D7S_RS09880 () | 1976034..1976978 | + | 945 | WP_005540351.1 | transketolase family protein | - |
| D7S_RS09885 () | 1977145..1978095 | - | 951 | WP_005549138.1 | 50S ribosomal protein L3 N(5)-glutamine methyltransferase | - |
| D7S_RS09890 () | 1978158..1978664 | + | 507 | WP_005540347.1 | endonuclease SmrB | - |
| D7S_RS09895 () | 1978661..1980802 | - | 2142 | WP_005540345.1 | TIGR01666 family membrane protein | - |
| D7S_RS09900 () | 1980811..1981284 | - | 474 | WP_005540343.1 | YccF domain-containing protein | - |
| D7S_RS09905 () | 1981284..1981742 | - | 459 | WP_005540341.1 | methylglyoxal synthase | - |
| D7S_RS09910 () | 1981805..1982485 | - | 681 | WP_005549145.1 | DUF2057 domain-containing protein | - |
| D7S_RS09915 () | 1982630..1982902 | + | 273 | WP_005540337.1 | acylphosphatase | - |
| D7S_RS09920 () | 1982877..1983725 | - | 849 | WP_005540335.1 | Manganese transport system membrane protein MntB | VF |
| D7S_RS09925 () | 1983722..1984579 | - | 858 | WP_005540332.1 | iron ABC transporter permease subunit AfeC | - |
| D7S_RS09930 () | 1984579..1985469 | - | 891 | WP_005540330.1 | Fe(3+) dicitrate transport ATP-binding protein FecE | VF |
| D7S_RS09935 () | 1985469..1986350 | - | 882 | WP_005540327.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| D7S_RS09940 () | 1986448..1986777 | - | 330 | WP_014702540.1 | TusE/DsrC/DsvC family sulfur relay protein | - |
| D7S_RS09945 () | 1986863..1987525 | - | 663 | WP_005540319.1 | BAX inhibitor protein | - |
| D7S_RS09950 () | 1987841..1988275 | + | 435 | WP_041160780.1 | CRISPR-associated endonuclease Cas3'' | - |
| D7S_RS09955 () | 1988306..1990091 | + | 1786 | Protein_1890 | CRISPR-associated helicase Cas3' | - |
| D7S_RS09960 () | 1990228..1993104 | + | 2877 | WP_014702542.1 | DEAD/DEAH box helicase | - |
| D7S_RS09965 () | 1993134..1993715 | + | 582 | WP_005540311.1 | hypothetical protein | - |
| D7S_RS09970 () | 1993712..1994653 | + | 942 | WP_005540309.1 | DUF4868 domain-containing protein | - |
| D7S_RS09975 () | 1994667..1996403 | + | 1737 | WP_005540307.1 | site-specific DNA-methyltransferase | - |
| D7S_RS09980 () | 1996530..1997564 | + | 1035 | WP_005540305.1 | virulence RhuM family protein | - |
| D7S_RS09985 () | 1997561..2000278 | + | 2718 | WP_005540302.1 | DEAD/DEAH box helicase family protein | - |
| D7S_RS09990 () | 2000393..2001067 | + | 675 | WP_005540300.1 | type I-C CRISPR-associated protein Cas5 | - |
| D7S_RS09995 () | 2001064..2002841 | + | 1778 | Protein_1898 | type I-C CRISPR-associated protein Cas8c/Csd1 | - |
| D7S_RS10000 () | 2002854..2003720 | + | 867 | WP_005540292.1 | type I-C CRISPR-associated protein Cas7/Csd2 | - |
| D7S_RS10005 () | 2003865..2004515 | + | 651 | WP_005540290.1 | CRISPR-associated protein Cas4 | - |
| D7S_RS10010 () | 2004542..2005285 | + | 744 | WP_005540287.1 | hypothetical protein | - |
| D7S_RS11745 () | 2005612..2005764 | + | 153 | Protein_1902 | CRISPR-associated endonuclease Cas2 | - |
| D7S_RS10020 () | 2006787..2007167 | + | 381 | WP_005540283.1 | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | - |
| D7S_RS10025 () | 2007189..2008193 | + | 1005 | WP_014702546.1 | thiamine ABC transporter substrate binding subunit | - |
| D7S_RS10030 () | 2008202..2009830 | + | 1629 | WP_005540278.1 | thiamine/thiamine pyrophosphate ABC transporter permease ThiP | - |
| D7S_RS10035 () | 2009814..2010461 | + | 648 | WP_005540276.1 | Thiamine import ATP-binding protein ThiQ | VF |
| D7S_RS10040 () | 2010507..2011511 | + | 1005 | WP_005540274.1 | Biotin synthase | VF |
| D7S_RS10045 () | 2012226..2012705 | + | 480 | WP_005540269.1 | leucine-responsive transcriptional regulator Lrp | - |
| D7S_RS10050 () | 2012709..2015453 | + | 2745 | WP_005595076.1 | DNA translocase FtsK | - |
| D7S_RS10055 () | 2015546..2016163 | + | 618 | WP_005540265.1 | outer membrane lipoprotein chaperone LolA | - |
| D7S_RS10060 () | 2016176..2017516 | + | 1341 | WP_005540264.1 | replication-associated recombination protein A | - |
| D7S_RS10065 () | 2018013..2019680 | - | 1668 | WP_005540262.1 | anaerobic C4-dicarboxylate transporter | - |
| D7S_RS10070 () | 2019987..2021303 | + | 1317 | WP_014702547.1 | serine--tRNA ligase | - |
| D7S_RS10075 () | 2021383..2022279 | - | 897 | WP_005549823.1 | cytidine deaminase | - |
| D7S_RS10080 () | 2022403..2023500 | - | 1098 | WP_005549825.1 | extracellular solute-binding protein | - |
| D7S_RS10085 () | 2023631..2024404 | - | 774 | WP_005542482.1 | spermidine/putrescine ABC transporter permease PotC | - |
| D7S_RS10090 () | 2024404..2025264 | - | 861 | WP_005542483.1 | spermidine/putrescine ABC transporter permease PotB | - |
| D7S_RS10095 () | 2025248..2026366 | - | 1119 | WP_005542484.1 | Spermidine/putrescine import ATP-binding protein PotA | VF |
| D7S_RS10100 () | 2026630..2027874 | + | 1245 | WP_005542485.1 | peptidase T | - |
| D7S_RS10105 () | 2027949..2030606 | - | 2658 | WP_014702549.1 | hypothetical protein | VF |
| D7S_RS10110 () | 2030569..2031852 | - | 1284 | WP_005542487.1 | paraquat-inducible protein A | - |
| D7S_RS10115 () | 2032055..2032681 | + | 627 | WP_005542488.1 | RNA chaperone ProQ | - |
| D7S_RS10120 () | 2032755..2034812 | + | 2058 | WP_005542489.1 | carboxy terminal-processing peptidase | - |
| D7S_RS10125 () | 2034890..2036398 | + | 1509 | WP_005542490.1 | L,D-transpeptidase family protein | - |
| D7S_RS10130 () | 2036463..2037023 | + | 561 | WP_005542491.1 | YcbK family protein | - |
| D7S_RS10135 () | 2037100..2037738 | + | 639 | WP_005542492.1 | MBL fold metallo-hydrolase | - |
| D7S_RS10140 () | 2038017..2040824 | + | 2808 | WP_044116053.1 | 2-oxoglutarate dehydrogenase E1 component | - |
| D7S_RS10145 () | 2040950..2042173 | + | 1224 | WP_005542495.1 | 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase | - |
| D7S_RS10150 () | 2042359..2043528 | + | 1170 | WP_005542496.1 | ADP-forming succinate--CoA ligase subunit beta | - |
| D7S_RS10155 () | 2043539..2044411 | + | 873 | WP_005542497.1 | succinate--CoA ligase subunit alpha | - |
| D7S_RS12070 () | 2044444..2045736 | + | 1293 | WP_014702551.1 | hypothetical protein | - |
| D7S_RS10175 () | 2045738..2046082 | + | 345 | WP_005544611.1 | hypothetical protein | - |
| D7S_RS10180 () | 2046245..2046568 | + | 324 | WP_005544613.1 | hypothetical protein | - |
| D7S_RS10185 () | 2046778..2048931 | - | 2154 | WP_079254144.1 | formate dehydrogenase subunit alpha | - |
| D7S_RS10190 () | 2049133..2050326 | - | 1194 | WP_005542183.1 | Fic family protein | - |
| D7S_RS10195 () | 2050454..2050915 | - | 462 | WP_005542184.1 | hydrogenase maturation peptidase HycI | - |
| D7S_RS10200 () | 2050905..2051309 | - | 405 | WP_005542185.1 | formate hydrogenlyase maturation HycH family protein | - |
| D7S_RS10205 () | 2051391..2052167 | - | 777 | WP_005542186.1 | NADH-quinone oxidoreductase subunit B family protein | - |
| D7S_RS10210 () | 2052164..2052811 | - | 648 | WP_005542187.1 | 4Fe-4S dicluster domain-containing protein | - |
| D7S_RS10215 () | 2052825..2054555 | - | 1731 | WP_005542188.1 | hydrogenase large subunit | - |
| D7S_RS10220 () | 2054575..2056113 | - | 1539 | WP_005549755.1 | hydrogenase 4 subunit F | - |
| D7S_RS10225 () | 2056118..2056756 | - | 639 | WP_005542193.1 | hydrogenase 4 membrane subunit | - |
| D7S_RS10230 () | 2056767..2058212 | - | 1446 | WP_005542195.1 | hydrogenase 4 subunit D | - |
| D7S_RS10235 () | 2058225..2059187 | - | 963 | WP_005542197.1 | respiratory chain complex I subunit 1 family protein | - |
| D7S_RS10240 () | 2059198..2061219 | - | 2022 | WP_005542199.1 | hydrogenase 4 subunit B | - |
| D7S_RS10245 () | 2061253..2061852 | - | 600 | WP_005549758.1 | 4Fe-4S dicluster domain-containing protein | - |
| D7S_RS10250 () | 2062145..2064430 | + | 2286 | WP_005542203.1 | carbamoyltransferase HypF | - |
| D7S_RS10255 () | 2065051..2065764 | - | 714 | WP_005542205.1 | formate dehydrogenase subunit gamma | - |
| D7S_RS10260 () | 2065757..2066674 | - | 918 | WP_167555044.1 | formate dehydrogenase subunit beta | - |
| D7S_RS10265 () | 2066685..2069774 | - | 3090 | WP_143247869.1 | formate dehydrogenase-N subunit alpha | - |
| D7S_RS10280 () | 2070016..2070840 | + | 825 | WP_005542212.1 | formate dehydrogenase accessory sulfurtransferase FdhD | - |
| D7S_RS10285 () | 2070889..2071887 | + | 999 | WP_005542214.1 | gluconate operon transcriptional repressor GntR | - |
| D7S_RS10290 () | 2071957..2072475 | - | 519 | WP_005542216.1 | gluconokinase | - |
| D7S_RS10295 () | 2072693..2074042 | + | 1350 | WP_014702554.1 | GntP family permease | - |
| D7S_RS10300 () | 2074215..2076389 | + | 2175 | WP_014702555.1 | DNA helicase II | - |
| D7S_RS10305 () | 2076521..2077348 | - | 828 | WP_005542220.1 | DNA ligase | - |
| D7S_RS10310 () | 2077525..2078268 | - | 744 | WP_014702556.1 | YdcF family protein | - |
| D7S_RS10315 () | 2078281..2078535 | - | 255 | WP_005549367.1 | Txe/YoeB family addiction module toxin | Toxin Detail |
| D7S_RS10320 () | 2078532..2078783 | - | 252 | WP_005552753.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin Detail |
| D7S_RS10325 () | 2078892..2079848 | - | 957 | WP_005542226.1 | polysaccharide pyruvyl transferase family protein | - |
| D7S_RS10330 () | 2079845..2081368 | - | 1524 | WP_005542228.1 | hypothetical protein | - |
| D7S_RS10335 () | 2081502..2082275 | + | 774 | WP_180267045.1 | hypothetical protein | VF |
| D7S_RS10340 () | 2082284..2083474 | + | 1191 | WP_005549375.1 | hypothetical protein | - |
| D7S_RS10345 () | 2083474..2084355 | + | 882 | WP_005540377.1 | PGL/p-HBAD biosynthesis glycosyltransferase | VF |
| D7S_RS10350 () | 2084430..2085233 | + | 804 | WP_005549377.1 | UDP-Gal:alpha-D-GlcNAc-diphosphoundecaprenol beta-1,3-galactosyltransferase | VF |
| D7S_RS10355 () | 2085235..2086377 | + | 1143 | WP_005549378.1 | lytic murein transglycosylase | - |
| D7S_RS10360 () | 2086395..2087198 | + | 804 | WP_005542405.1 | exodeoxyribonuclease III | - |
| D7S_RS10365 () | 2087198..2087986 | + | 789 | WP_005542406.1 | TIGR01619 family protein | - |
| D7S_RS11750 () | 2088011..2089039 | + | 1029 | WP_005542407.1 | dTDP-glucose 4,6-dehydratase 2 | VF |
| D7S_RS10380 () | 2089201..2089941 | - | 741 | WP_005542409.1 | hypothetical protein | - |
| D7S_RS10385 () | 2090216..2090869 | - | 654 | WP_005542410.1 | GTP cyclohydrolase II | - |
| D7S_RS10390 () | 2090946..2091686 | + | 741 | WP_005542411.1 | phosphatase PAP2 family protein | - |
| D7S_RS10395 () | 2091737..2092651 | + | 915 | WP_005542412.1 | N-acetylglucosamine kinase | - |
| D7S_RS10400 () | 2092708..2093293 | - | 586 | Protein_1974 | DUF1439 domain-containing protein | - |
| D7S_RS10405 () | 2093381..2094016 | + | 636 | WP_005542415.1 | hypothetical protein | - |
| D7S_RS10410 () | 2094082..2094822 | + | 741 | WP_005542416.1 | protein kinase family protein | - |
| D7S_RS10415 () | 2095031..2095963 | - | 933 | WP_005542418.1 | acyl-CoA thioesterase II | - |
| D7S_RS10425 () | 2096214..2097947 | - | 1734 | WP_005542419.1 | cysteine/glutathione ABC transporter ATP-binding protein/permease CydC | - |
| D7S_RS10430 () | 2097947..2099710 | - | 1764 | WP_032998675.1 | cysteine/glutathione ABC transporter permease/ATP-binding protein CydD | - |
| D7S_RS10435 () | 2099816..2100769 | - | 954 | WP_005542421.1 | thioredoxin-disulfide reductase | - |
| D7S_RS10440 () | 2100829..2101686 | - | 858 | WP_005542422.1 | co-chaperone YbbN | - |
| D7S_RS10445 () | 2101905..2102331 | + | 427 | Protein_1982 | IS4/IS5 family transposase | - |
| D7S_RS10450 () | 2102406..2103137 | - | 732 | WP_005542424.1 | molybdopterin-synthase adenylyltransferase MoeB | - |
| D7S_RS10455 () | 2103153..2104367 | - | 1215 | WP_005542426.1 | molybdopterin molybdotransferase MoeA | - |
| D7S_RS10460 () | 2104496..2105152 | + | 657 | WP_005542427.1 | GTP cyclohydrolase I FolE | - |
| D7S_RS10465 () | 2105253..2106695 | - | 1443 | WP_005542428.1 | serine-type D-Ala-D-Ala carboxypeptidase | - |
| D7S_RS10470 () | 2106855..2107331 | + | 477 | WP_005542429.1 | transcription elongation factor GreA | - |
| D7S_RS10475 () | 2107407..2107709 | - | 303 | WP_005542430.1 | ribosome assembly RNA-binding protein YhbY | - |
| D7S_RS10480 () | 2107877..2108176 | + | 300 | WP_005542431.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| D7S_RS10485 () | 2108173..2108469 | + | 297 | WP_005542432.1 | putative addiction module antidote protein | Antitoxin Detail |
| D7S_RS10490 () | 2108502..2109116 | - | 615 | WP_005542433.1 | riboflavin synthase | - |
| D7S_RS10495 () | 2109143..2110540 | + | 1398 | WP_005542434.1 | MATE family efflux transporter | - |
| D7S_RS10500 () | 2110812..2112950 | + | 2139 | WP_005542435.1 | TonB-dependent siderophore receptor | - |
| D7S_RS10505 () | 2113004..2114749 | + | 1746 | WP_005542436.1 | ABC transporter ATP-binding protein/permease | - |
| D7S_RS10510 () | 2114863..2115342 | - | 480 | WP_005542438.1 | Cys-tRNA(Pro) deacylase | - |
| D7S_RS10515 () | 2115403..2116374 | + | 972 | WP_005542439.1 | oxidoreductase | - |
| D7S_RS10520 () | 2116980..2118713 | - | 1734 | WP_005550377.1 | arginine--tRNA ligase | - |
| D7S_RS10525 () | 2118810..2119397 | + | 588 | WP_014702560.1 | VOC family protein | - |
| D7S_RS10530 () | 2119439..2119894 | + | 456 | WP_005542443.1 | glycine zipper 2TM domain-containing protein | - |
| D7S_RS10535 () | 2120035..2121117 | + | 1083 | WP_005542444.1 | peptide chain release factor 1 | - |
| D7S_RS10540 () | 2121157..2122056 | + | 900 | WP_005542445.1 | peptide chain release factor N(5)-glutamine methyltransferase | - |
| D7S_RS10545 () | 2122066..2122920 | + | 855 | WP_005542446.1 | 2-dehydro-3-deoxyphosphooctonate aldolase | VF |
| D7S_RS10550 () | 2123100..2123609 | + | 510 | WP_005542447.1 | Murein DD-endopeptidase MepS/Murein LD-carboxypeptidase | VF |
| D7S_RS10555 () | 2123778..2123963 | + | 186 | WP_005581143.1 | hypothetical protein | - |
| D7S_RS10560 () | 2124007..2124258 | - | 252 | WP_005542449.1 | YcgL domain-containing protein | - |
| D7S_RS10565 () | 2124342..2125004 | + | 663 | WP_005542450.1 | septum site-determining protein MinC | - |
| D7S_RS10570 () | 2125026..2125571 | - | 546 | WP_005542451.1 | hypothetical protein | - |
| D7S_RS10575 () | 2125795..2126262 | - | 468 | WP_005542452.1 | phosphohistidine phosphatase SixA | - |
| D7S_RS10580 () | 2126275..2127612 | - | 1338 | WP_005551246.1 | phosphoglucosamine mutase | - |
| D7S_RS10585 () | 2127640..2128467 | - | 828 | WP_005552864.1 | dihydropteroate synthase | - |
| D7S_RS10590 () | 2128637..2129719 | - | 1083 | Protein_2011 | DNA polymerase IV | - |
| D7S_RS11925 () | 2129758..2129850 | - | 93 | WP_158511708.1 | IS3 family transposase | - |
| D7S_RS11760 () | 2129813..2130277 | - | 465 | WP_079254134.1 | IS3 family transposase ISHar1 | Transposase |
| D7S_RS11765 () | 2130259..2130516 | - | 258 | WP_145916692.1 | IS3 family transposase ISBce15 | Transposase |
| D7S_RS10600 () | 2130558..2130933 | - | 376 | Protein_2015 | transposase | - |
| D7S_RS11770 () | 2131056..2131244 | - | 189 | WP_143106533.1 | hypothetical protein | - |
| D7S_RS10605 () | 2131418..2131867 | + | 450 | WP_005544663.1 | type VI secretion protein ImpA | - |
| D7S_RS11775 () | 2131934..2132005 | - | 72 | WP_109091998.1 | IS3 family transposase | - |
| D7S_RS12095 () | 2132100..2132473 | - | 374 | Protein_2019 | transposase | - |
| D7S_RS10615 () | 2132575..2134041 | - | 1467 | WP_005544504.1 | IMP dehydrogenase | - |
| D7S_RS10620 () | 2134183..2135111 | + | 929 | Protein_2021 | bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | - |
| D7S_RS10625 () | 2135202..2135405 | + | 204 | WP_005551084.1 | glycine zipper 2TM domain-containing protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|