MGE detailed information
MGE type: Conjugative plasmid MGE length: 147060 bp
Accession: NC_017659 Location: 1..147060 Organism: Escherichia coli O83:H1 str. NRG 857C Replicon: plasmid pO83_CORR
Accession: NC_017659 Location: 1..147060 Organism: Escherichia coli O83:H1 str. NRG 857C Replicon: plasmid pO83_CORR
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NRG857_RS22770 () | 1..1076 | + | 1076 | Protein_0 | IS481 family transposase ISKpn28 | Transposase |
| NRG857_RS22775 () | 2313..3428 | + | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| NRG857_RS22780 () | 3568..7227 | + | 3660 | WP_001111199.1 | Multidrug efflux ATP-binding/permease protein | VF |
| NRG857_RS22785 () | 7331..8560 | + | 1230 | WP_000933675.1 | Enterochelin esterase | VF |
| NRG857_RS22790 () | 8645..9601 | + | 957 | WP_000271276.1 | Ferri-bacillibactin esterase BesA | VF |
| NRG857_RS22795 () | 9646..11823 | - | 2178 | WP_001222186.1 | Ferric enterobactin receptor | VF |
| NRG857_RS22800 () | 12678..13466 | - | 789 | Protein_6 | 3-deoxy-7-phosphoheptulonate synthase | - |
| NRG857_RS22805 () | 13611..14579 | - | 969 | WP_000654811.1 | IS5 family transposase IS903B | Transposase |
| NRG857_RS22810 () | 14599..14847 | + | 249 | WP_032300423.1 | Toxin RTX-I translocation ATP-binding protein | VF |
| NRG857_RS22815 () | 15017..15328 | - | 312 | WP_001259758.1 | colicin V | - |
| NRG857_RS22820 () | 15306..15542 | - | 237 | WP_014640552.1 | colicin V immunity protein | - |
| NRG857_RS22825 () | 16006..16287 | - | 282 | WP_001105066.1 | hypothetical protein | - |
| NRG857_RS22830 () | 16460..16627 | + | 168 | Protein_12 | colicin-B | - |
| NRG857_RS22835 () | 16645..17172 | - | 528 | WP_000203272.1 | colicin B immunity protein | - |
| NRG857_RS22840 () | 17416..18231 | + | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
| NRG857_RS22845 () | 18281..18634 | - | 354 | WP_000864812.1 | colicin M immunity protein | - |
| NRG857_RS22850 () | 18812..19603 | - | 792 | WP_000016493.1 | site-specific integrase | - |
| NRG857_RS22855 () | 19600..20289 | - | 690 | WP_000796228.1 | hypothetical protein | - |
| NRG857_RS22860 () | 20333..20683 | - | 351 | WP_000493379.1 | hypothetical protein | - |
| NRG857_RS22865 () | 21227..22315 | + | 1089 | WP_000952217.1 | transcriptional repressor PifC | - |
| NRG857_RS22870 () | 22317..24542 | + | 2226 | WP_000698737.1 | phage T7 exclusion protein | - |
| NRG857_RS22875 () | 24592..25491 | - | 900 | WP_000963206.1 | nucleotide-binding protein | - |
| NRG857_RS22880 () | 25481..25771 | - | 291 | WP_000111771.1 | hypothetical protein | - |
| NRG857_RS22885 () | 26067..26297 | + | 231 | WP_001261287.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| NRG857_RS22890 () | 26294..26710 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| NRG857_RS22895 () | 26872..29010 | - | 2139 | WP_000350638.1 | AAA family ATPase | - |
| NRG857_RS22900 () | 29364..29621 | + | 258 | WP_000343085.1 | hypothetical protein | - |
| NRG857_RS22905 () | 29621..30211 | + | 591 | WP_000194575.1 | hypothetical protein | - |
| NRG857_RS22910 () | 30474..32030 | + | 1557 | WP_000818556.1 | AAA family ATPase | - |
| NRG857_RS22915 () | 32221..32838 | + | 618 | WP_000521603.1 | hypothetical protein | - |
| NRG857_RS22920 () | 33131..34264 | - | 1134 | WP_001089728.1 | permease | - |
| NRG857_RS22925 () | 34369..34692 | + | 324 | WP_001175594.1 | helix-turn-helix domain-containing protein | - |
| NRG857_RS22930 () | 34747..36498 | - | 1752 | Protein_32 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| NRG857_RS22935 () | 36487..36894 | + | 408 | WP_001214976.1 | cysteine hydrolase | - |
| NRG857_RS22940 () | 37032..37916 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| NRG857_RS22945 () | 37948..39147 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| NRG857_RS22950 () | 39253..39903 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| NRG857_RS22955 () | 39935..40177 | - | 243 | WP_000844627.1 | transposase | - |
| NRG857_RS22960 () | 40491..42239 | + | 1749 | Protein_38 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| NRG857_RS22965 () | 42306..42683 | + | 378 | WP_000656305.1 | GNAT family N-acetyltransferase | - |
| NRG857_RS22970 () | 42884..43543 | - | 660 | WP_000412211.1 | Chloramphenicol acetyltransferase | ARG |
| NRG857_RS22975 () | 43822..44519 | + | 698 | Protein_41 | IS1 family transposase | - |
| NRG857_RS22980 () | 45232..45936 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| NRG857_RS22985 () | 46148..47008 | - | 861 | WP_000027062.1 | Beta-lactamase TEM | ARG |
| NRG857_RS22990 () | 47191..47529 | - | 339 | Protein_44 | Tn3 family transposase TnpR_Tn3 | Transposase |
| NRG857_RS22995 () | 47593..48297 | + | 705 | WP_001067855.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| NRG857_RS23000 () | 48347..49066 | + | 720 | Protein_46 | AAA family ATPase | - |
| NRG857_RS23005 () | 49053..49904 | + | 852 | WP_000240536.1 | replication protein | - |
| NRG857_RS23015 () | 50212..51027 | + | 816 | WP_001043265.1 | Dihydropteroate synthase | ARG |
| NRG857_RS23020 () | 51088..51891 | + | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| NRG857_RS23025 () | 51891..52727 | + | 837 | WP_000480968.1 | hypothetical protein | ARG |
| NRG857_RS23030 () | 52699..53817 | - | 1119 | WP_000845049.1 | IS91 family transposase ISAzo26 | Transposase |
| NRG857_RS23035 () | 53974..54447 | + | 474 | WP_000777555.1 | Dihydrofolate reductase type 1 | ARG |
| NRG857_RS23040 () | 54540..55331 | + | 792 | WP_001206317.1 | Streptomycin 3''-adenylyltransferase | ARG |
| NRG857_RS23045 () | 55495..55842 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| NRG857_RS23050 () | 55836..56675 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| NRG857_RS23055 () | 56803..57303 | + | 501 | WP_000376623.1 | GNAT family N-acetyltransferase | - |
| NRG857_RS23060 () | 57479..58261 | - | 783 | WP_001163403.1 | IS21 family transposase IS1326 | Transposase |
| NRG857_RS23065 () | 58251..59774 | - | 1524 | WP_001324342.1 | IS21 family transposase IS1326 | Transposase |
| NRG857_RS23070 () | 59876..60604 | - | 729 | WP_000059618.1 | IS91 family transposase ISPps1 | Transposase |
| NRG857_RS23075 () | 60686..60964 | + | 279 | WP_001611016.1 | diguanylate cyclase | - |
| NRG857_RS23080 () | 60972..61223 | - | 252 | WP_000928197.1 | hypothetical protein | - |
| NRG857_RS23085 () | 61154..61975 | + | 822 | WP_014640556.1 | serine hydrolase | - |
| NRG857_RS23090 () | 62877..63494 | + | 618 | WP_000451766.1 | TetR/AcrR family transcriptional regulator | - |
| NRG857_RS23095 () | 63531..64370 | + | 840 | WP_000140042.1 | alpha/beta fold hydrolase | - |
| NRG857_RS23100 () | 64407..65315 | + | 909 | WP_000031017.1 | hypothetical protein | ARG |
| NRG857_RS23105 () | 65427..65693 | + | 267 | WP_071779295.1 | helix-turn-helix domain-containing protein | - |
| NRG857_RS23110 () | 65834..67501 | - | 1668 | WP_000344783.1 | IS91 family transposase ISVsa3 | Transposase |
| NRG857_RS23115 () | 67504..69183 | - | 1680 | WP_000179844.1 | DDE-type integrase/transposase/recombinase | - |
| NRG857_RS23120 () | 69258..69926 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| NRG857_RS23125 () | 69962..70198 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| NRG857_RS23130 () | 70195..70557 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| NRG857_RS23135 () | 70575..72269 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| NRG857_RS23140 () | 72321..72743 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| NRG857_RS23145 () | 72779..73054 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| NRG857_RS23150 () | 73068..73418 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| NRG857_RS23155 () | 73490..73924 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| NRG857_RS23160 () | 74031..74728 | - | 698 | Protein_77 | IS1 family transposase | - |
| NRG857_RS23165 () | 75093..75494 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| NRG857_RS23170 () | 75427..75684 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| NRG857_RS23175 () | 75777..76430 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| NRG857_RS23180 () | 77370..78227 | - | 858 | WP_000774303.1 | incFII family plasmid replication initiator RepA | - |
| NRG857_RS23185 () | 78220..78702 | - | 483 | WP_001273588.1 | hypothetical protein | - |
| NRG857_RS23190 () | 78695..78769 | - | 75 | WP_001442103.1 | RepA leader peptide Tap | - |
| NRG857_RS23195 () | 79001..79258 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| NRG857_RS23200 () | 79542..79748 | - | 207 | WP_001351576.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 79735..79796 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 79735..79796 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 79735..79796 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 79735..79796 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| NRG857_RS23610 () | 80052..80126 | - | 75 | Protein_86 | endonuclease | - |
| NRG857_RS23205 () | 80372..80584 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| NRG857_RS23210 () | 80720..81280 | - | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| NRG857_RS23215 () | 81383..82243 | - | 861 | WP_000704527.1 | putative protein YcjY | VF |
| NRG857_RS23220 () | 82302..83048 | - | 747 | WP_000205766.1 | conjugal transfer pilus acetylase TraX | - |
| NRG857_RS23225 () | 83068..88338 | - | 5271 | WP_000986959.1 | Multifunctional conjugation protein TraI | Relaxase |
| NRG857_RS23230 () | 88420..88647 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| NRG857_RS23235 () | 88647..89045 | + | 399 | WP_000911313.1 | tRNA(fMet)-specific endonuclease VapC | Toxin Detail |
| NRG857_RS23240 () | 89054..91207 | - | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
| NRG857_RS23245 () | 91460..92191 | - | 732 | WP_023565183.1 | complement resistance protein TraT | - |
| NRG857_RS23250 () | 92223..92720 | - | 498 | WP_000605857.1 | entry exclusion protein | - |
| NRG857_RS23255 () | 92736..95558 | - | 2823 | WP_001007018.1 | conjugal transfer mating pair stabilization protein TraG | - |
| NRG857_RS23615 () | 95555..95935 | - | 381 | Protein_98 | conjugal transfer protein TraH | - |
| NRG857_RS23260 () | 96017..96865 | - | 849 | Protein_99 | F-type conjugal transfer pilus assembly protein TraB | - |
| NRG857_RS23265 () | 96865..97569 | - | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| NRG857_RS23270 () | 97580..98146 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| NRG857_RS23275 () | 98168..98479 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| NRG857_RS23280 () | 98494..98859 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| NRG857_RS23285 () | 98892..99287 | - | 396 | WP_014640559.1 | conjugal transfer relaxosome protein TraY | - |
| NRG857_RS23290 () | 99386..100075 | - | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| NRG857_RS23295 () | 100262..100645 | - | 384 | WP_001151524.1 | relaxosome protein TraM | - |
| NRG857_RS23300 () | 100966..101568 | + | 603 | WP_000243712.1 | hypothetical protein | VF |
| NRG857_RS23305 () | 101864..102685 | - | 822 | WP_001234426.1 | DUF945 domain-containing protein | - |
| NRG857_RS23310 () | 102803..103090 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| NRG857_RS23320 () | 104011..104169 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 104213..104437 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 104213..104437 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 104213..104437 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 104213..104437 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| NRG857_RS23325 () | 104249..104437 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| NRG857_RS23330 () | 104449..105168 | - | 720 | WP_001276238.1 | plasmid SOS inhibition protein A | - |
| NRG857_RS23335 () | 105165..105599 | - | 435 | WP_000845936.1 | conjugation system SOS inhibitor PsiB | - |
| NRG857_RS23340 () | 105654..105851 | - | 198 | Protein_114 | hypothetical protein | - |
| NRG857_RS23345 () | 105879..106112 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| NRG857_RS23350 () | 106185..106724 | - | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
| NRG857_RS23620 () | 106750..106956 | - | 207 | WP_000275856.1 | hypothetical protein | - |
| NRG857_RS23365 () | 108052..109023 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| NRG857_RS23370 () | 109023..110189 | - | 1167 | WP_001238646.1 | Sporulation initiation inhibitor protein Soj | VF |
| NRG857_RS23375 () | 110489..111186 | - | 698 | Protein_120 | IS1 family transposase | - |
| NRG857_RS23380 () | 111671..113872 | - | 2202 | WP_000973511.1 | Ferric aerobactin receptor | VF |
| NRG857_RS23385 () | 113954..115231 | - | 1278 | WP_000750130.1 | L-lysine N6-monooxygenase | VF |
| NRG857_RS23390 () | 115228..116970 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| NRG857_RS23395 () | 116970..117917 | - | 948 | WP_000011910.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| NRG857_RS23400 () | 117918..119642 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| NRG857_RS23405 () | 119778..120971 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| NRG857_RS23410 () | 121351..121731 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| NRG857_RS23415 () | 122072..122485 | - | 414 | Protein_128 | phosphopyruvate hydratase | - |
| NRG857_RS23420 () | 122483..122740 | + | 258 | Protein_129 | Tn3 family transposase | - |
| NRG857_RS23425 () | 122974..123831 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| NRG857_RS23430 () | 123828..124685 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| NRG857_RS23435 () | 124682..125509 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| NRG857_RS23440 () | 125481..126422 | - | 942 | WP_014640564.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| NRG857_RS23445 () | 126778..127475 | + | 698 | Protein_134 | IS1 family transposase | - |
| NRG857_RS23450 () | 127655..128168 | - | 514 | Protein_135 | DUF4113 domain-containing protein | - |
| NRG857_RS23625 () | 128229..128333 | - | 105 | Protein_136 | AAA family ATPase | - |
| NRG857_RS23455 () | 128335..128658 | - | 324 | Protein_137 | IS21 family transposase IS21 | Transposase |
| NRG857_RS23460 () | 129404..130381 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| NRG857_RS23465 () | 130666..131406 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| NRG857_RS23470 () | 131527..131715 | - | 189 | WP_014640565.1 | hypothetical protein | - |
| NRG857_RS23475 () | 132089..132991 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| NRG857_RS23480 () | 133060..134169 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| NRG857_RS23485 () | 134602..135555 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| NRG857_RS23490 () | 136828..136986 | - | 159 | WP_001312823.1 | integrase core domain-containing protein | - |
| NRG857_RS23495 () | 137170..138383 | + | 1214 | WP_162842477.1 | IS3 family transposase IS629 | Transposase |
| NRG857_RS23500 () | 138531..138799 | - | 269 | Protein_146 | IS3 family transposase ISLad1 | Transposase |
| NRG857_RS23505 () | 138856..139553 | + | 698 | Protein_147 | IS1 family transposase | - |
| NRG857_RS23510 () | 139631..141020 | - | 1390 | Protein_148 | ISNCY family transposase ISKpn21 | Transposase |
| NRG857_RS23515 () | 141330..141479 | - | 150 | Protein_149 | IS3 family transposase IS2 | Transposase |
| NRG857_RS23520 () | 141657..142850 | - | 1194 | WP_000450494.1 | GTP-binding protein | - |
| NRG857_RS23525 () | 144073..145309 | - | 1237 | Protein_151 | IS3 family transposase IS2 | Transposase |
| NRG857_RS23530 () | 145936..146229 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| NRG857_RS23535 () | 146287..146486 | - | 200 | Protein_153 | lysis protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|