MGE detailed information
MGE type: Conjugative plasmid MGE length: 97978 bp
Accession: NC_011603 Location: 1..97978 Organism: Escherichia coli O127:H6 str. E2348/69 Replicon: plasmid pMAR2
Accession: NC_011603 Location: 1..97978 Organism: Escherichia coli O127:H6 str. E2348/69 Replicon: plasmid pMAR2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| E2348C_RS25350 () | 263..1252 | + | 990 | WP_024201093.1 | RepB family plasmid replication initiator protein | - |
| E2348C_RS25355 () | 1575..2225 | - | 651 | Protein_1 | tyrosine-type recombinase/integrase | - |
| E2348C_RS25365 () | 2646..3227 | + | 582 | WP_000253757.1 | Major structural subunit of bundle-forming pilus | VF |
| E2348C_RS25370 () | 3274..3675 | + | 402 | WP_001261182.1 | hypothetical protein | VF |
| E2348C_RS25375 () | 3682..5340 | + | 1659 | WP_000766020.1 | Outer membrane lipoprotein BfpB | VF |
| E2348C_RS25380 () | 5337..6545 | + | 1209 | WP_000594644.1 | hypothetical protein | VF |
| E2348C_RS25385 () | 6523..7017 | + | 495 | WP_000464849.1 | hypothetical protein | VF |
| E2348C_RS25390 () | 7024..8631 | + | 1608 | WP_012477166.1 | Toxin coregulated pilus biosynthesis protein T | VF |
| E2348C_RS25395 () | 8638..9696 | + | 1059 | WP_000660204.1 | Toxin coregulated pilus biosynthesis protein E | VF |
| E2348C_RS25400 () | 9680..10675 | + | 996 | WP_001183608.1 | ComG operon protein 1 | VF |
| E2348C_RS25405 () | 10682..11431 | + | 750 | WP_001158204.1 | Leader peptidase PppA | VF |
| E2348C_RS25410 () | 11413..11859 | + | 447 | WP_012477167.1 | hypothetical protein | VF |
| E2348C_RS25415 () | 11880..12425 | + | 546 | WP_000470346.1 | hypothetical protein | VF |
| E2348C_RS25420 () | 12422..12973 | + | 552 | WP_000619594.1 | hypothetical protein | VF |
| E2348C_RS25425 () | 12963..13451 | + | 489 | WP_000575683.1 | hypothetical protein | VF |
| E2348C_RS25430 () | 13454..13903 | + | 450 | WP_000896065.1 | hypothetical protein | VF |
| E2348C_RS26145 () | 14191..15151 | + | 961 | Protein_16 | IS481 family transposase | - |
| E2348C_RS25445 () | 15191..15379 | - | 189 | WP_000468315.1 | hypothetical protein | - |
| E2348C_RS28045 () | 16758..16904 | + | 147 | Protein_19 | IS1 family transposase | - |
| E2348C_RS28605 () | 17176..18000 | + | 825 | WP_000958124.1 | BFP system transcriptional regulator PerA | - |
| E2348C_RS25465 () | 18048..18437 | + | 390 | WP_000794576.1 | protein PerB | - |
| E2348C_RS25470 () | 18487..18756 | + | 270 | WP_000405638.1 | PerC family transcriptional regulator | - |
| E2348C_RS28050 () | 18981..19785 | - | 805 | Protein_23 | IS256 family transposase IS1414 | Transposase |
| E2348C_RS25490 () | 19865..20879 | + | 1015 | Protein_24 | IS4 family transposase ISSfl1 | Transposase |
| E2348C_RS25495 () | 20911..21387 | + | 477 | Protein_25 | Flp pilus assembly complex ATPase component TadA | - |
| E2348C_RS28610 () | 21677..22255 | - | 579 | WP_000039533.1 | Major structural subunit of bundle-forming pilus | VF |
| E2348C_RS25510 () | 22792..23916 | + | 1125 | Protein_27 | transposase | - |
| E2348C_RS25515 () | 24113..24598 | - | 486 | WP_029694820.1 | GNAT family N-acetyltransferase | - |
| E2348C_RS25525 () | 24572..26540 | + | 1969 | Protein_29 | hypothetical protein | VF |
| E2348C_RS28615 () | 26597..27023 | + | 427 | Protein_30 | IS3 family transposase | - |
| E2348C_RS25535 () | 27091..27527 | - | 437 | Protein_31 | IS21 family transposase IS21 | Transposase |
| E2348C_RS25540 () | 27540..28058 | - | 519 | Protein_32 | IS21 family transposase IS21 | Transposase |
| E2348C_RS25545 () | 28145..29136 | + | 992 | Protein_33 | IS21 family transposase IS100kyp | Transposase |
| E2348C_RS25550 () | 29133..29402 | + | 270 | Protein_34 | IS21 family transposase IS100 | Transposase |
| E2348C_RS25555 () | 29608..29895 | - | 288 | WP_000222766.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| E2348C_RS25560 () | 29892..30143 | - | 252 | WP_001132900.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| E2348C_RS25565 () | 30216..30407 | - | 192 | WP_000841007.1 | hypothetical protein | - |
| E2348C_RS25570 () | 31108..31965 | - | 858 | WP_000131012.1 | incFII family plasmid replication initiator RepA | - |
| E2348C_RS25575 () | 31958..32032 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| E2348C_RS25580 () | 32279..32527 | - | 249 | WP_000083838.1 | replication regulatory protein RepA | - |
| E2348C_RS26150 () | 32811..32960 | - | 150 | WP_001300273.1 | type I toxin-antitoxin system Hok family toxin | - |
| E2348C_RS25585 () | 33149..34522 | + | 1374 | WP_000244358.1 | IS4 family transposase ISEc13 | Transposase |
| E2348C_RS25590 () | 34555..35112 | - | 558 | WP_000139319.1 | fertility inhibition protein FinO | - |
| E2348C_RS25595 () | 35215..36075 | - | 861 | WP_000704512.1 | putative protein YcjY | VF |
| E2348C_RS25600 () | 36134..36880 | - | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| E2348C_RS25605 () | 36900..42170 | - | 5271 | WP_000986966.1 | Multifunctional conjugation protein TraI | Relaxase |
| E2348C_RS25610 () | 42252..42479 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| E2348C_RS25615 () | 42479..42877 | + | 399 | WP_000911313.1 | tRNA(fMet)-specific endonuclease VapC | Toxin Detail |
| E2348C_RS25620 () | 42886..45039 | - | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
| E2348C_RS25625 () | 45292..46023 | - | 732 | WP_000850423.1 | complement resistance protein TraT | - |
| E2348C_RS25630 () | 46037..46546 | - | 510 | WP_000628106.1 | conjugal transfer entry exclusion protein TraS | - |
| E2348C_RS25635 () | 46543..49368 | - | 2826 | WP_001007001.1 | conjugal transfer mating pair stabilization protein TraG | - |
| E2348C_RS25640 () | 49365..50738 | - | 1374 | WP_000488447.1 | conjugal transfer protein TraH | - |
| E2348C_RS25645 () | 50738..51151 | - | 414 | WP_071781708.1 | F-type conjugal transfer protein TrbF | - |
| E2348C_RS25650 () | 51105..51446 | - | 342 | WP_012477176.1 | P-type conjugative transfer protein TrbJ | - |
| E2348C_RS25655 () | 51376..51921 | - | 546 | WP_000059835.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| E2348C_RS25660 () | 51908..52192 | - | 285 | WP_000624108.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| E2348C_RS25665 () | 52273..52587 | + | 315 | WP_000415570.1 | hypothetical protein | - |
| E2348C_RS25670 () | 52589..52936 | - | 348 | WP_001287909.1 | conjugal transfer protein TrbA | - |
| E2348C_RS25675 () | 52952..53695 | - | 744 | WP_001030379.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| E2348C_RS25680 () | 53688..53945 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| E2348C_RS25685 () | 53973..55781 | - | 1809 | WP_000821827.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| E2348C_RS25690 () | 55778..56416 | - | 639 | WP_000777697.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| E2348C_RS25695 () | 56425..57417 | - | 993 | WP_000830821.1 | conjugal transfer pilus assembly protein TraU | - |
| E2348C_RS25700 () | 57414..58046 | - | 633 | WP_001203740.1 | type-F conjugative transfer system protein TraW | - |
| E2348C_RS25705 () | 58043..58429 | - | 387 | WP_000214079.1 | type-F conjugative transfer system protein TrbI | - |
| E2348C_RS25710 () | 58426..61053 | - | 2628 | WP_001064253.1 | type IV secretion system protein TraC | - |
| E2348C_RS28080 () | 61213..61434 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| E2348C_RS25720 () | 61569..62084 | - | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| E2348C_RS25725 () | 62081..62332 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| E2348C_RS25730 () | 62325..62678 | - | 354 | WP_071791934.1 | conjugal transfer protein TrbD | - |
| E2348C_RS25735 () | 62632..63222 | - | 591 | WP_000002788.1 | conjugal transfer protein TraP | - |
| E2348C_RS25740 () | 63212..64639 | - | 1428 | WP_000146685.1 | conjugal transfer protein TraB | - |
| E2348C_RS25745 () | 64639..65343 | - | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| E2348C_RS25750 () | 65354..65920 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| E2348C_RS25755 () | 65942..66253 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| E2348C_RS25760 () | 66268..66633 | - | 366 | WP_000340270.1 | type IV conjugative transfer system pilin TraA | - |
| E2348C_RS25765 () | 66667..66894 | - | 228 | WP_012477178.1 | conjugal transfer relaxosome protein TraY | - |
| E2348C_RS25770 () | 66989..67675 | - | 687 | WP_000332491.1 | PAS domain-containing protein | - |
| E2348C_RS25775 () | 67865..68248 | - | 384 | WP_000124981.1 | relaxosome protein TraM | - |
| E2348C_RS25780 () | 68593..69183 | + | 591 | WP_172682412.1 | hypothetical protein | VF |
| E2348C_RS25785 () | 69479..70300 | - | 822 | WP_001234454.1 | DUF945 domain-containing protein | - |
| E2348C_RS28705 () | 70419..70616 | - | 198 | WP_134810086.1 | hypothetical protein | - |
| E2348C_RS28830 () | 70730..70849 | - | 120 | WP_014106970.1 | hypothetical protein | - |
| E2348C_RS28835 () | 71082..71383 | + | 302 | Protein_85 | pilus protein | - |
| E2348C_RS28095 () | 71406..71558 | - | 153 | Protein_86 | class I SAM-dependent methyltransferase | - |
| E2348C_RS25805 () | 71571..72944 | - | 1374 | WP_000244358.1 | IS4 family transposase ISEc13 | Transposase |
| E2348C_RS25810 () | 73051..73527 | - | 477 | WP_000556070.1 | class I SAM-dependent methyltransferase | - |
| E2348C_RS25815 () | 73574..74935 | - | 1362 | WP_000170720.1 | DUF3560 domain-containing protein | - |
| E2348C_RS25820 () | 74987..75205 | - | 219 | WP_032163416.1 | hypothetical protein | - |
| E2348C_RS28895 () | 75896..76225 | + | 330 | Protein_91 | pilus assembly protein | - |
| E2348C_RS25835 () | 76204..76395 | - | 192 | WP_001027497.1 | hypothetical protein | - |
| E2348C_RS25840 () | 76395..76814 | - | 420 | WP_000271711.1 | DUF1380 family protein | - |
| E2348C_RS25845 () | 76861..77163 | - | 303 | WP_001436678.1 | antirestriction protein | - |
| E2348C_RS25855 () | 77856..78578 | + | 723 | Protein_95 | IS110 family transposase ISOt5 | Transposase |
| E2348C_RS25860 () | 78652..78909 | + | 258 | Protein_96 | IS3 family transposase IS911 | Transposase |
| E2348C_RS25865 () | 78922..80073 | - | 1152 | WP_001254946.1 | IS30 family transposase IS30D | Transposase |
| E2348C_RS25870 () | 80138..80734 | + | 597 | Protein_98 | IS3 family transposase IS911 | Transposase |
| E2348C_RS25875 () | 81016..82092 | + | 1077 | WP_000907654.1 | IS110 family transposase ISEc21 | Transposase |
| E2348C_RS25880 () | 82109..82417 | + | 309 | Protein_100 | DDE-type integrase/transposase/recombinase | - |
| E2348C_RS25885 () | 82426..82602 | + | 177 | Protein_101 | IS1 family transposase | - |
| E2348C_RS26160 () | 82840..83325 | + | 486 | WP_001386133.1 | glutamate decarboxylase A subunit | - |
| E2348C_RS28630 () | 83306..83542 | + | 237 | WP_071589304.1 | hypothetical protein | - |
| E2348C_RS25895 () | 83582..85042 | + | 1461 | WP_000063567.1 | amino acid permease | - |
| E2348C_RS25900 () | 85076..85885 | + | 810 | WP_000490358.1 | glutamate racemase | - |
| E2348C_RS28635 () | 87223..88211 | + | 989 | Protein_107 | translesion error-prone DNA polymerase V subunit UmuC | - |
| E2348C_RS25925 () | 88216..88608 | - | 393 | WP_000340833.1 | plasmid partitioning/stability family protein | - |
| E2348C_RS25930 () | 88613..89584 | - | 972 | WP_001103698.1 | hypothetical protein | - |
| E2348C_RS25935 () | 89813..90457 | + | 645 | WP_000633911.1 | AAA family ATPase | - |
| E2348C_RS25940 () | 90451..90726 | + | 276 | WP_000239529.1 | hypothetical protein | - |
| E2348C_RS25945 () | 90864..91673 | - | 810 | WP_000016979.1 | site-specific integrase | - |
| E2348C_RS25950 () | 91674..91979 | - | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| E2348C_RS25955 () | 91981..92199 | - | 219 | WP_000813637.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| E2348C_RS25960 () | 92913..95534 | + | 2622 | WP_000283686.1 | hypothetical protein | - |
| E2348C_RS25965 () | 95733..95963 | + | 231 | WP_001261274.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| E2348C_RS28900 () | 96139..96327 | + | 189 | WP_001386137.1 | hypothetical protein | - |
| E2348C_RS28840 () | 96332..96549 | - | 218 | Protein_118 | transposase | - |
| E2348C_RS25975 () | 96550..97080 | - | 531 | WP_000348885.1 | GNAT family N-acetyltransferase | - |
| E2348C_RS25980 () | 97084..97353 | - | 270 | WP_001275013.1 | DUF1778 domain-containing protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|