MGE detailed information
MGE type: Conjugative plasmid MGE length: 130440 bp
Accession: NC_010488 Location: 1..130440 Organism: Escherichia coli SMS-3-5 Replicon: plasmid pSMS35_130
Accession: NC_010488 Location: 1..130440 Organism: Escherichia coli SMS-3-5 Replicon: plasmid pSMS35_130
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ECSMS35_RS24935 () | 904..1761 | - | 858 | WP_000130940.1 | incFII family plasmid replication initiator RepA | - |
| ECSMS35_RS24940 () | 1754..1828 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| ECSMS35_RS24945 () | 2054..2314 | - | 261 | WP_000083818.1 | replication regulatory protein RepA | - |
| ECSMS35_RS27730 () | 2553..3126 | - | 574 | Protein_3 | DUF2726 domain-containing protein | - |
| ECSMS35_RS24955 () | 3164..3373 | - | 210 | WP_001333231.1 | hemolysin expression modulator Hha | - |
| ECSMS35_RS24960 () | 3419..3880 | - | 462 | WP_001233871.1 | thermonuclease family protein | - |
| ECSMS35_RS24965 () | 4123..4335 | - | 213 | WP_012311405.1 | hypothetical protein | - |
| ECSMS35_RS24970 () | 4473..5033 | - | 561 | WP_000139359.1 | fertility inhibition protein FinO | - |
| ECSMS35_RS24975 () | 5088..5834 | - | 747 | WP_000205777.1 | conjugal transfer pilus acetylase TraX | - |
| ECSMS35_RS24980 () | 5854..11124 | - | 5271 | WP_000986979.1 | Multifunctional conjugation protein TraI | Relaxase |
| ECSMS35_RS24985 () | 11124..13295 | - | 2172 | WP_000009362.1 | type IV conjugative transfer system coupling protein TraD | - |
| ECSMS35_RS24990 () | 13548..14279 | - | 732 | WP_000850422.1 | complement resistance protein TraT | - |
| ECSMS35_RS24995 () | 14311..14814 | - | 504 | WP_000605510.1 | hypothetical protein | - |
| ECSMS35_RS25000 () | 14829..17651 | - | 2823 | WP_001007026.1 | conjugal transfer mating pair stabilization protein TraG | - |
| ECSMS35_RS25005 () | 17648..19021 | - | 1374 | WP_001137358.1 | conjugal transfer protein TraH | - |
| ECSMS35_RS25010 () | 19021..19383 | - | 363 | WP_001443292.1 | P-type conjugative transfer protein TrbJ | - |
| ECSMS35_RS25015 () | 19313..19858 | - | 546 | WP_000052618.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| ECSMS35_RS25020 () | 19845..20129 | - | 285 | WP_000624110.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| ECSMS35_RS25025 () | 20248..20595 | - | 348 | WP_001287893.1 | conjugal transfer protein TrbA | - |
| ECSMS35_RS25030 () | 20611..21354 | - | 744 | WP_001030378.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| ECSMS35_RS25035 () | 21347..21604 | - | 258 | WP_000864325.1 | conjugal transfer protein TrbE | - |
| ECSMS35_RS25040 () | 21631..23439 | - | 1809 | WP_000821821.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| ECSMS35_RS25045 () | 23436..24074 | - | 639 | WP_001104248.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| ECSMS35_RS25050 () | 24102..24554 | - | 453 | WP_000069427.1 | hypothetical protein | - |
| ECSMS35_RS25055 () | 24584..25045 | - | 462 | WP_000277845.1 | hypothetical protein | - |
| ECSMS35_RS25060 () | 25071..26063 | - | 993 | WP_000830839.1 | conjugal transfer pilus assembly protein TraU | - |
| ECSMS35_RS25065 () | 26060..26692 | - | 633 | WP_001203745.1 | type-F conjugative transfer system protein TraW | - |
| ECSMS35_RS25070 () | 26689..27075 | - | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| ECSMS35_RS25075 () | 27072..29699 | - | 2628 | WP_001064268.1 | type IV secretion system protein TraC | - |
| ECSMS35_RS27735 () | 29859..30080 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| ECSMS35_RS25085 () | 30215..30730 | - | 516 | WP_000809906.1 | type IV conjugative transfer system lipoprotein TraV | - |
| ECSMS35_RS25090 () | 30727..30978 | - | 252 | WP_001038341.1 | conjugal transfer protein TrbG | - |
| ECSMS35_RS25095 () | 30975..31292 | - | 318 | WP_001057292.1 | conjugal transfer protein TrbD | - |
| ECSMS35_RS25100 () | 31289..31861 | - | 573 | WP_000002780.1 | conjugal transfer protein TraP | - |
| ECSMS35_RS25105 () | 31851..33278 | - | 1428 | WP_000146685.1 | conjugal transfer protein TraB | - |
| ECSMS35_RS25110 () | 33278..33982 | - | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| ECSMS35_RS25115 () | 33993..34559 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| ECSMS35_RS25120 () | 34581..34892 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| ECSMS35_RS25125 () | 34907..35266 | - | 360 | WP_000340272.1 | type IV conjugative transfer system pilin TraA | - |
| ECSMS35_RS25130 () | 35300..35527 | - | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| ECSMS35_RS25135 () | 35621..36307 | - | 687 | WP_000332484.1 | PAS domain-containing protein | - |
| ECSMS35_RS25140 () | 36498..36881 | - | 384 | WP_000124981.1 | relaxosome protein TraM | - |
| ECSMS35_RS25145 () | 37158..37805 | + | 648 | WP_000614936.1 | hypothetical protein | VF |
| ECSMS35_RS25150 () | 38102..38923 | - | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| ECSMS35_RS25155 () | 39046..39333 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| ECSMS35_RS28535 () | 39358..39564 | - | 207 | WP_000547939.1 | hypothetical protein | - |
| ECSMS35_RS25165 () | 40255..40413 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 40457..40681 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 40457..40681 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 40457..40681 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 40457..40681 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| ECSMS35_RS29575 () | 40493..40681 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| ECSMS35_RS25175 () | 40693..41412 | - | 720 | WP_001276228.1 | plasmid SOS inhibition protein A | - |
| ECSMS35_RS25180 () | 41409..41843 | - | 435 | WP_000845895.1 | conjugation system SOS inhibitor PsiB | - |
| ECSMS35_RS25185 () | 41898..43856 | - | 1959 | WP_001145469.1 | ParB/RepB/Spo0J family partition protein | - |
| ECSMS35_RS25190 () | 43915..44148 | - | 234 | WP_000006004.1 | DUF905 domain-containing protein | - |
| ECSMS35_RS25195 () | 44204..44731 | - | 528 | WP_000290793.1 | single-stranded DNA-binding protein | - |
| ECSMS35_RS28545 () | 45204..45470 | - | 267 | WP_072254135.1 | hypothetical protein | - |
| ECSMS35_RS25205 () | 45622..46185 | - | 564 | WP_001311069.1 | class I SAM-dependent methyltransferase | - |
| ECSMS35_RS25210 () | 46231..47592 | - | 1362 | WP_000170681.1 | DUF3560 domain-containing protein | - |
| ECSMS35_RS25215 () | 47644..47874 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| ECSMS35_RS29580 () | 48552..48880 | + | 329 | Protein_57 | pilus assembly protein | - |
| ECSMS35_RS25225 () | 48868..49050 | - | 183 | WP_001027505.1 | hypothetical protein | - |
| ECSMS35_RS25230 () | 49050..49511 | - | 462 | WP_042007484.1 | DUF1380 family protein | - |
| ECSMS35_RS25235 () | 49511..49813 | - | 303 | WP_072256028.1 | antirestriction protein | - |
| ECSMS35_RS25240 () | 50338..51309 | + | 972 | WP_000082154.1 | IS110 family transposase ISEc32 | Transposase |
| ECSMS35_RS25245 () | 51362..52059 | - | 698 | Protein_62 | IS1 family transposase | - |
| ECSMS35_RS25250 () | 52113..52445 | - | 333 | Protein_63 | hypothetical protein | - |
| ECSMS35_RS29585 () | 52514..52852 | - | 339 | WP_001513511.1 | hypothetical protein | - |
| ECSMS35_RS25260 () | 53664..54635 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| ECSMS35_RS25265 () | 54635..55801 | - | 1167 | WP_001238646.1 | hypothetical protein | VF |
| ECSMS35_RS25270 () | 56101..56798 | - | 698 | Protein_67 | IS1 family transposase | - |
| ECSMS35_RS25275 () | 56954..58456 | - | 1503 | WP_000715078.1 | hypothetical protein | - |
| ECSMS35_RS25280 () | 59056..59505 | - | 450 | WP_000238252.1 | hypothetical protein | - |
| ECSMS35_RS25285 () | 59623..60102 | + | 480 | WP_000190053.1 | hypothetical protein | - |
| ECSMS35_RS25290 () | 60542..60769 | + | 228 | Protein_71 | malate dehydrogenase | - |
| ECSMS35_RS27805 () | 60766..60897 | - | 132 | Protein_72 | phosphopyruvate hydratase | - |
| ECSMS35_RS28570 () | 60895..61152 | + | 258 | Protein_73 | Tn3 family transposase | - |
| ECSMS35_RS25295 () | 61386..62243 | - | 858 | WP_000968140.1 | Manganese transport system membrane protein MntB | ARG |
| ECSMS35_RS25300 () | 62240..63097 | - | 858 | WP_000992806.1 | Manganese transport system membrane protein MntB | ARG |
| ECSMS35_RS25305 () | 63094..63921 | - | 828 | WP_000983710.1 | Manganese transport system ATP-binding protein MntB | VF |
| ECSMS35_RS25310 () | 63921..64835 | - | 915 | WP_000949004.1 | putative periplasmic iron-binding protein | VF |
| ECSMS35_RS25315 () | 65191..65888 | + | 698 | Protein_78 | IS1 family transposase IS1S | Transposase |
| ECSMS35_RS25320 () | 66068..66581 | - | 514 | Protein_79 | DUF4113 domain-containing protein | - |
| ECSMS35_RS29070 () | 66642..66746 | - | 105 | Protein_80 | AAA family ATPase | - |
| ECSMS35_RS25325 () | 66748..67071 | - | 324 | Protein_81 | IS21 family transposase IS21 | Transposase |
| ECSMS35_RS28580 () | 67320..68533 | + | 1214 | WP_085947772.1 | IS3 family transposase ISCfr6 | Transposase |
| ECSMS35_RS25355 () | 69078..70055 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| ECSMS35_RS25360 () | 70340..71080 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| ECSMS35_RS25365 () | 71201..71389 | - | 189 | WP_014640565.1 | hypothetical protein | - |
| ECSMS35_RS25370 () | 71763..72665 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| ECSMS35_RS25375 () | 72734..73843 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| ECSMS35_RS25385 () | 74276..75229 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| ECSMS35_RS27835 () | 76502..76660 | - | 159 | WP_001312823.1 | integrase core domain-containing protein | - |
| ECSMS35_RS25405 () | 76844..78057 | + | 1214 | WP_162842477.1 | IS3 family transposase IS629 | Transposase |
| ECSMS35_RS27840 () | 78205..78473 | - | 269 | Protein_91 | IS3 family transposase ISLad1 | Transposase |
| ECSMS35_RS25410 () | 78530..79227 | + | 698 | Protein_92 | IS1 family transposase | - |
| ECSMS35_RS25415 () | 79238..79441 | - | 204 | WP_001259759.1 | colicin V family bacteriocin | - |
| ECSMS35_RS29395 () | 79419..79655 | - | 237 | WP_014640552.1 | colicin V immunity protein | - |
| ECSMS35_RS25430 () | 80119..80400 | - | 282 | WP_001105066.1 | hypothetical protein | - |
| ECSMS35_RS28595 () | 80573..80740 | + | 168 | Protein_96 | colicin-B | - |
| ECSMS35_RS27855 () | 80758..80871 | - | 114 | Protein_97 | colicin immunity protein Cui | - |
| ECSMS35_RS25440 () | 80964..82192 | + | 1229 | WP_089541817.1 | IS3 family transposase IS2 | Transposase |
| ECSMS35_RS25445 () | 82202..82621 | - | 420 | Protein_99 | colicin B immunity protein | - |
| ECSMS35_RS25450 () | 82865..83680 | + | 816 | WP_000449474.1 | lipid II-degrading bacteriocin colicin M | - |
| ECSMS35_RS25455 () | 83730..84083 | - | 354 | WP_000864812.1 | colicin M immunity protein | - |
| ECSMS35_RS25460 () | 84261..85052 | - | 792 | WP_000016493.1 | site-specific integrase | - |
| ECSMS35_RS25470 () | 85373..86077 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ECSMS35_RS27865 () | 86130..86792 | - | 663 | Protein_104 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| ECSMS35_RS25480 () | 86858..87562 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ECSMS35_RS25485 () | 87706..88347 | - | 642 | WP_001011939.1 | Chloramphenicol acetyltransferase 2 | ARG |
| ECSMS35_RS25490 () | 88497..88997 | - | 501 | WP_001239317.1 | hypothetical protein | - |
| ECSMS35_RS25495 () | 89077..89781 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ECSMS35_RS25505 () | 90229..91242 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| ECSMS35_RS25510 () | 91398..91871 | + | 474 | WP_004201280.1 | Dihydrofolate reductase type 1 | ARG |
| ECSMS35_RS25515 () | 91941..92645 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ECSMS35_RS25520 () | 92699..93013 | + | 315 | Protein_112 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| ECSMS35_RS25525 () | 93016..95982 | + | 2967 | WP_001138070.1 | Tn3 family transposase TnpA_ISPa38 | Transposase |
| ECSMS35_RS25530 () | 96061..97065 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| ECSMS35_RS25535 () | 97247..97423 | - | 177 | WP_000954592.1 | Arm DNA-binding domain-containing protein | - |
| ECSMS35_RS25540 () | 97753..98568 | + | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| ECSMS35_RS25545 () | 98629..99432 | + | 804 | WP_001082320.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| ECSMS35_RS25550 () | 99432..100268 | + | 837 | WP_000480972.1 | hypothetical protein | ARG |
| ECSMS35_RS25555 () | 100499..101359 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| ECSMS35_RS25560 () | 101542..101823 | - | 282 | Protein_120 | Tn3 family transposase TnpR_Tn3 | Transposase |
| ECSMS35_RS25565 () | 101886..102590 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ECSMS35_RS27890 () | 102643..103029 | - | 387 | Protein_122 | IS91 family transposase ISAzo26 | Transposase |
| ECSMS35_RS25570 () | 103196..104038 | + | 843 | WP_001456218.1 | alpha/beta fold putative hydrolase EstX | - |
| ECSMS35_RS25575 () | 104134..104742 | + | 609 | WP_000050382.1 | HAD-IB family hydrolase | - |
| ECSMS35_RS25580 () | 104800..105591 | + | 792 | WP_001261740.1 | Streptomycin 3''-adenylyltransferase | ARG |
| ECSMS35_RS25585 () | 105733..106437 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ECSMS35_RS27900 () | 106500..107216 | + | 717 | Protein_127 | exclusion suppressor FxsA | - |
| ECSMS35_RS25600 () | 107266..108165 | - | 900 | WP_000963206.1 | nucleotide-binding protein | - |
| ECSMS35_RS25605 () | 108155..108445 | - | 291 | WP_000111771.1 | hypothetical protein | - |
| ECSMS35_RS25610 () | 108741..108971 | + | 231 | WP_001261287.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| ECSMS35_RS25615 () | 108968..109384 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| ECSMS35_RS25620 () | 109546..111684 | - | 2139 | WP_000350637.1 | AAA family ATPase | - |
| ECSMS35_RS25625 () | 112038..112295 | + | 258 | WP_000343085.1 | hypothetical protein | - |
| ECSMS35_RS25630 () | 112295..112885 | + | 591 | WP_000194575.1 | hypothetical protein | - |
| ECSMS35_RS25635 () | 113148..114704 | + | 1557 | WP_000818556.1 | AAA family ATPase | - |
| ECSMS35_RS25640 () | 114896..115513 | + | 618 | WP_000521603.1 | hypothetical protein | - |
| ECSMS35_RS25645 () | 115806..116885 | - | 1080 | WP_001089727.1 | permease | - |
| ECSMS35_RS25650 () | 116990..117313 | + | 324 | WP_001175594.1 | helix-turn-helix domain-containing protein | - |
| ECSMS35_RS27905 () | 117414..117794 | + | 381 | Protein_139 | NAD(P)H-dependent oxidoreductase | - |
| ECSMS35_RS25655 () | 117847..118551 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ECSMS35_RS25660 () | 118617..119474 | + | 858 | Protein_141 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| ECSMS35_RS25665 () | 119532..119774 | + | 243 | WP_000844627.1 | transposase | - |
| ECSMS35_RS25670 () | 119806..120456 | - | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| ECSMS35_RS25675 () | 120562..121761 | + | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| ECSMS35_RS25680 () | 121793..122677 | - | 885 | WP_000058717.1 | EamA family transporter | - |
| ECSMS35_RS25685 () | 122815..123222 | - | 408 | WP_001214976.1 | cysteine hydrolase | - |
| ECSMS35_RS25690 () | 123214..124887 | + | 1674 | Protein_147 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| ECSMS35_RS25695 () | 124842..125546 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ECSMS35_RS25700 () | 125612..125896 | + | 285 | Protein_149 | IS6 family transposase IS26 | Transposase |
| ECSMS35_RS25705 () | 126086..126901 | - | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| ECSMS35_RS25710 () | 127052..127756 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ECSMS35_RS25715 () | 127822..128367 | + | 546 | Protein_152 | Tn3 family transposase TnpA_Tn3 | Transposase |
| ECSMS35_RS27915 () | 128403..128818 | - | 416 | Protein_153 | IS1 family transposase | - |
| ECSMS35_RS25725 () | 129067..129468 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| ECSMS35_RS29400 () | 129401..129658 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| ECSMS35_RS25735 () | 129751..130404 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|