MGE detailed information
MGE type: Conjugative plasmid MGE length: 94281 bp
Accession: NC_002134 Location: 1..94281 Organism: Shigella flexneri 2b Replicon: plasmid R100
Accession: NC_002134 Location: 1..94281 Organism: Shigella flexneri 2b Replicon: plasmid R100
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HXF40_RS00005 (D742_p2099) | 92..526 | - | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| HXF40_RS00010 (D742_p2098) | 598..948 | + | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| HXF40_RS00015 (D742_p2100) | 962..1237 | + | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| HXF40_RS00020 (D742_p2104) | 1273..1695 | + | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| HXF40_RS00025 (D742_p2105) | 1747..3441 | + | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| HXF40_RS00030 (D742_p2103) | 3459..3821 | + | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| HXF40_RS00035 (D742_p2041) | 3818..4054 | + | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| HXF40_RS00040 (D742_p2040) | 4090..4758 | + | 669 | WP_001300294.1 | putative signaling protein | VF |
| HXF40_RS00045 (D742_p2080) | 4833..6512 | + | 1680 | WP_000179844.1 | DDE-type integrase/transposase/recombinase | - |
| HXF40_RS00050 (D742_p2079) | 6515..7375 | + | 861 | WP_000344784.1 | TniB family NTP-binding protein | - |
| HXF40_RS00055 (D742_p2039) | 7426..8970 | - | 1545 | WP_000287615.1 | IS3 family transposase IS1353 | Transposase |
| HXF40_RS00060 (D742_p2107) | 9093..10616 | + | 1524 | WP_001324342.1 | IS21 family transposase IS1326 | Transposase |
| HXF40_RS00065 (D742_p2106) | 10603..11388 | + | 786 | WP_000983249.1 | IS21 family transposase IS1326 | Transposase |
| HXF40_RS00070 (D742_p2038) | 11564..12064 | - | 501 | WP_000376623.1 | GNAT family N-acetyltransferase | - |
| HXF40_RS00075 (D742_p2086) | 12192..13031 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| HXF40_RS00080 (D742_p2090) | 13025..13372 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| HXF40_RS00085 (D742_p2114) | 13489..14327 | - | 839 | Protein_16 | Streptomycin 3''-adenylyltransferase | ARG |
| HXF40_RS00090 (D742_p2108) | 14476..15489 | + | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| HXF40_RS00095 (D742_p2043) | 15692..16042 | + | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| HXF40_RS00100 (D742_p2042) | 16168..16728 | + | 561 | WP_000147567.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| HXF40_RS00105 (D742_p2044) | 16731..19697 | + | 2967 | WP_001138064.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| HXF40_RS00110 (D742_p2037) | 19764..20141 | + | 378 | WP_000656305.1 | GNAT family N-acetyltransferase | - |
| HXF40_RS00115 (D742_p2112) | 20342..21001 | - | 660 | WP_000412211.1 | Chloramphenicol acetyltransferase | ARG |
| HXF40_RS00120 (D742_p2109) | 21280..21977 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| HXF40_RS00125 | 23426..23660 | + | 235 | Protein_24 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| HXF40_RS00130 (D742_p2035) | 23788..24069 | + | 282 | WP_001333089.1 | hypothetical protein | - |
| HXF40_RS00135 (D742_p2087) | 24192..24542 | - | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
| HXF40_RS00140 (D742_p2088) | 24545..25507 | - | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| HXF40_RS00145 | 25654..25947 | + | 294 | WP_032146011.1 | hypothetical protein | - |
| HXF40_RS00150 (D742_p2034) | 26024..26707 | + | 684 | WP_000085883.1 | DNA methylase | - |
| HXF40_RS00155 | 26708..26929 | + | 222 | WP_001104881.1 | hypothetical protein | - |
| HXF40_RS00160 (D742_p2033) | 26943..27377 | + | 435 | WP_000274503.1 | DUF1380 family protein | - |
| HXF40_RS00165 (D742_p2032) | 27428..28204 | + | 777 | WP_001383963.1 | hypothetical protein | - |
| HXF40_RS00170 (D742_p2030) | 28622..29047 | + | 426 | WP_001198898.1 | antirestriction protein | - |
| HXF40_RS00175 (D742_p2029) | 29094..29516 | + | 423 | WP_000271722.1 | DUF1380 family protein | - |
| HXF40_RS00180 | 29513..29704 | + | 192 | WP_001027516.1 | hypothetical protein | - |
| HXF40_RS00185 (D742_p2026) | 30761..30991 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| HXF40_RS00190 (D742_p2025) | 31043..32404 | + | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| HXF40_RS00195 (D742_p2024) | 32451..33014 | + | 564 | WP_001298559.1 | class I SAM-dependent methyltransferase | - |
| HXF40_RS00575 | 33100..33567 | - | 468 | Protein_39 | hypothetical protein | - |
| HXF40_RS00205 (D742_p2089) | 33869..34396 | + | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| HXF40_RS00210 (D742_p2022) | 34454..34687 | + | 234 | WP_000006003.1 | DUF905 family protein | - |
| HXF40_RS00215 (D742_p2021) | 34748..36130 | + | 1383 | Protein_42 | ParB/RepB/Spo0J family partition protein | - |
| HXF40_RS00220 (D742_p2020) | 36239..37447 | + | 1209 | WP_001352368.1 | IS4 family transposase IS10R | Transposase |
| HXF40_RS00225 | 37463..37582 | - | 120 | Protein_44 | LysR family transcriptional regulator | - |
| HXF40_RS00230 (D742_p2019) | 37813..39018 | - | 1206 | WP_000599533.1 | sodium/glutamate symporter | - |
| HXF40_RS00235 (D742_p2018) | 39462..39782 | + | 321 | WP_000562370.1 | antibiotic biosynthesis monooxygenase | - |
| HXF40_RS00240 (D742_p2017) | 39775..40161 | + | 387 | WP_000460651.1 | hypothetical protein | - |
| HXF40_RS00245 (D742_p2016) | 40169..40855 | + | 687 | WP_001284954.1 | winged helix-turn-helix domain-containing protein | - |
| HXF40_RS00250 (D742_p2081) | 40833..41456 | - | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| HXF40_RS00255 (D742_p2084) | 41538..42743 | + | 1206 | WP_001089072.1 | Tetracycline resistance protein, class B | ARG |
| HXF40_RS00260 (D742_p2083) | 42856..43449 | - | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| HXF40_RS00265 (D742_p2082) | 43537..43953 | + | 417 | WP_000275180.1 | Transposon Tn10 TetD protein | VF |
| HXF40_RS00270 (D742_p2015) | 43963..45171 | - | 1209 | WP_001339197.1 | IS4 family transposase IS10R | Transposase |
| HXF40_RS00275 (D742_p2003) | 45281..45868 | + | 588 | Protein_54 | hypothetical protein | - |
| HXF40_RS00280 (D742_p2091) | 45937..46371 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| HXF40_RS00285 (D742_p2092) | 46368..47087 | + | 720 | WP_001276217.1 | plasmid SOS inhibition protein A | - |
| - | 47256..47321 | + | 66 | - | - | Antitoxin Detail |
| HXF40_RS00580 | 47309..47458 | + | 150 | Protein_57 | plasmid maintenance protein Mok | - |
| HXF40_RS00290 (D742_p2111) | 47400..47525 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| HXF40_RS00295 (D742_p2002) | 47844..48140 | - | 297 | Protein_59 | hypothetical protein | - |
| HXF40_RS00300 (D742_p2001) | 48440..48736 | + | 297 | WP_001272251.1 | hypothetical protein | - |
| HXF40_RS00305 (D742_p2116) | 48847..49668 | + | 822 | WP_001234445.1 | DUF932 domain-containing protein | - |
| HXF40_RS00310 (D742_p2045) | 49965..50567 | - | 603 | WP_000243713.1 | hypothetical protein | VF |
| HXF40_RS00315 (D742_p2066) | 50890..51273 | + | 384 | WP_001354030.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| HXF40_RS00320 (D742_p2069) | 51467..52138 | + | 672 | WP_000283561.1 | conjugal transfer transcriptional regulator TraJ | - |
| HXF40_RS00325 (D742_p2055) | 52275..52502 | + | 228 | WP_000089263.1 | conjugal transfer relaxosome protein TraY | - |
| HXF40_RS00330 (D742_p2078) | 52535..52894 | + | 360 | WP_001098992.1 | type IV conjugative transfer system pilin TraA | - |
| HXF40_RS00335 (D742_p2067) | 52909..53220 | + | 312 | WP_000012113.1 | type IV conjugative transfer system protein TraL | - |
| HXF40_RS00340 (D742_p2074) | 53242..53808 | + | 567 | WP_000399780.1 | type IV conjugative transfer system protein TraE | - |
| HXF40_RS00345 (D742_p2068) | 53795..54523 | + | 729 | WP_001230772.1 | type-F conjugative transfer system secretin TraK | - |
| HXF40_RS00350 (D742_p2077) | 54523..55974 | + | 1452 | WP_000146675.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| HXF40_RS00355 (D742_p2064) | 55964..56530 | + | 567 | WP_000896599.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| HXF40_RS00360 (D742_p2050) | 56517..56837 | + | 321 | WP_001057307.1 | conjugal transfer protein TrbD | - |
| HXF40_RS00365 (D742_p2058) | 56834..57349 | + | 516 | WP_000809881.1 | type IV conjugative transfer system lipoprotein TraV | - |
| HXF40_RS00370 (D742_p2062) | 57484..57705 | + | 222 | WP_001278683.1 | conjugal transfer protein TraR | - |
| HXF40_RS00375 (D742_p2014) | 57698..58111 | + | 414 | WP_000549589.1 | hypothetical protein | - |
| HXF40_RS00380 (D742_p2013) | 58104..58577 | + | 474 | WP_000549568.1 | hypothetical protein | - |
| HXF40_RS00385 (D742_p2012) | 58657..58875 | + | 219 | WP_000556745.1 | hypothetical protein | - |
| HXF40_RS00390 (D742_p2011) | 58903..59250 | + | 348 | WP_000836682.1 | hypothetical protein | - |
| HXF40_RS00395 (D742_p2076) | 59376..62006 | + | 2631 | WP_000069777.1 | type IV secretion system protein TraC | - |
| HXF40_RS00400 (D742_p2047) | 62003..62389 | + | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| HXF40_RS00405 (D742_p2057) | 62386..63018 | + | 633 | WP_001203728.1 | type-F conjugative transfer system protein TraW | - |
| HXF40_RS00410 (D742_p2059) | 63015..64007 | + | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| HXF40_RS00415 (D742_p2010) | 64037..64342 | + | 306 | WP_000224416.1 | hypothetical protein | - |
| HXF40_RS00420 (D742_p2051) | 64351..64989 | + | 639 | WP_001080256.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| HXF40_RS00425 | 64986..66836 | + | 1851 | Protein_85 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| HXF40_RS00430 (D742_p2049) | 66863..67120 | + | 258 | WP_000864353.1 | conjugal transfer protein TrbE | - |
| HXF40_RS00435 (D742_p2073) | 67113..67856 | + | 744 | WP_001030371.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| HXF40_RS00440 (D742_p2053) | 67870..68214 | + | 345 | WP_000556796.1 | conjugal transfer protein TrbA | - |
| HXF40_RS00445 (D742_p2063) | 68333..68617 | + | 285 | WP_000624194.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| HXF40_RS00450 (D742_p2052) | 68604..69149 | + | 546 | WP_000059831.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| HXF40_RS00455 (D742_p2046) | 69079..69426 | + | 348 | WP_001309242.1 | P-type conjugative transfer protein TrbJ | - |
| HXF40_RS00460 (D742_p2048) | 69407..69799 | + | 393 | WP_000660699.1 | F-type conjugal transfer protein TrbF | - |
| HXF40_RS00465 (D742_p2071) | 69786..71159 | + | 1374 | WP_000944331.1 | conjugal transfer pilus assembly protein TraH | - |
| HXF40_RS00470 (D742_p2072) | 71156..73978 | + | 2823 | WP_001007039.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| HXF40_RS00475 (D742_p2061) | 73994..74479 | + | 486 | WP_000605870.1 | hypothetical protein | - |
| HXF40_RS00480 (D742_p2060) | 74528..75259 | + | 732 | WP_000782451.1 | conjugal transfer complement resistance protein TraT | - |
| HXF40_RS00485 (D742_p2009) | 75462..76199 | + | 738 | WP_000199905.1 | hypothetical protein | - |
| HXF40_RS00490 (D742_p2075) | 76250..78466 | + | 2217 | WP_000009331.1 | type IV conjugative transfer system coupling protein TraD | - |
| HXF40_RS00495 (D742_p2070) | 78466..83736 | + | 5271 | WP_000948354.1 | Multifunctional conjugation protein TraI | Relaxase |
| HXF40_RS00500 (D742_p2056) | 83756..84502 | + | 747 | WP_000205725.1 | conjugal transfer pilus acetylase TraX | - |
| HXF40_RS00505 (D742_p2004) | 84561..85421 | + | 861 | WP_000704523.1 | Quorum-quenching protein AidA | VF |
| HXF40_RS00510 (D742_p2117) | 85524..86084 | + | 561 | WP_000139321.1 | fertility inhibition protein FinO | - |
| HXF40_RS00515 (D742_p2008) | 86213..86425 | + | 213 | WP_001309245.1 | ANR family transcriptional regulator | - |
| HXF40_RS00520 (D742_p2007) | 86669..87130 | + | 462 | WP_001233850.1 | thermonuclease family protein | - |
| HXF40_RS00525 | 87176..87385 | + | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| HXF40_RS00530 (D742_p2006) | 87423..88013 | + | 591 | WP_000766807.1 | DUF2726 domain-containing protein | - |
| HXF40_RS00535 (D742_p2096) | 88253..88507 | + | 255 | WP_000083830.1 | replication regulatory protein RepA | - |
| HXF40_RS00540 (D742_p2094) | 88745..88819 | + | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| HXF40_RS00545 (D742_p2097) | 88812..89669 | + | 858 | WP_000130646.1 | incFII family plasmid replication initiator RepA | - |
| HXF40_RS00550 (D742_p2085) | 90608..91261 | + | 654 | WP_000616807.1 | CPBP family intramembrane glutamic endopeptidase | - |
| HXF40_RS00555 (D742_p2102) | 91354..91611 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | Antitoxin Detail |
| HXF40_RS00560 (D742_p2101) | 91544..91945 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | Toxin Detail |
| HXF40_RS00565 (D742_p2005) | 92230..93540 | + | 1311 | WP_001262765.1 | DUF262 domain-containing protein | - |
| HXF40_RS00570 (D742_p2113) | 93569..94266 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|