| Effector Protein ID: 54298775 |
 T4SS name [ID] | Dot/Icm [40] |
| Gene symbol | lepA |
| Locus tag | lpp2839 |
| Strain | Legionella pneumophila str. Paris |
| Replicon | chromosome [GenBank: NC_006368] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 3230473..3233832 [+] |
| Product | effector protein A, substrate of the Dot/Icm secretion system |
| Effector type | Protein |
| Descripton | LepA |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Bacterial egress |
| UniProt ID | Q5X1A4 |
| KEGG ID | lpp:lpp2839 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 1119 a.a. [Download] |
| >gi|54298775|ref|YP_125144.1| effector protein A, substrate of the Dot/Icm secretion system [Legionella pneumophila str. Paris] MNEIILHLMNEISALTPPINPLNLKQIFSSTLLPEGKAPVEVESQLNLLLLIKKHVDEYSSLAEEQDEYK RKKQKQDEVMKKGEELQRKISDLAKKIELAKSELNPLYKEIEPKANEVLSKQNPLAPPYKFPEYGEVQKS IVVGHYSYLFKTSKEIETTRAKLKLVLLKNKWHALMTDLSQLGIQPPVEEDAVDSLQKFTAAVELEIKKL TRSCEKWDELQKRFAKQLSATDINKKETELEKQIELLLKDLGRIEATVTNHSLVPDLKAELIRKFQESED PQGLIQEYQNQIDGILSNFNPSSWLSWYSDSSYSDKQQKLKDSVSFLQLLAQQKELKIKHHELVKQQELL IKAIPETRSNEEDISIYKKLVPDAIDLINEIPIQSIPNFVLPSGLSYDSSPADFYLVLLILMPKVSEKKE QYSQALEKLQEMPALGKQIHQLRSGYDLPATMDVQLPSLQEAEENKDTLNTEDPLKEELQSQIKLCQSYL ETAKQIDLLMKNHGQTTNEAKALIEQLRLISNQPLKNEDINSIKEDLSTLANQIQSLVSELNQLPLPNLT GEKIDPSLEKQEIAVDKAIPITVELMHPAQVFQIGNDSHLEKRQQDNEEETPVVLESSRPHQVIHQEPES LVELGQIDNGHEIPVVLESTHPPQIIHTESESAGKKQRVEVEQEIPVVLELTRPSSMVEKDSGVTVEKLE VAERQDTPIVLESTRSTPMVQKDSGLSGEKQHKEIEQEIPAVPELTLRPQVVQQGSESSEEQQVPNGQET LAVVKSSPSEPLRPSTPEVPVISRKPNGLSLFNGHDELSEDNILAFFDEAGNQITISSEEDSETLAIDRG KVNSLGIDKAFKEEPVSTGHELDKLSNPQHQESAPNISPLPPSSILLKQKLDSFHVQNMEYIKQQSEEIQ LWYKGLYDAAQSSCLNEALGLKALHLFKDILFELKNQNDLSVLLAYKRMCPNPLQDIQNILRLKPALPIL DESIDEEQQLKNWPEELQKFHQQYVKLKKEHPLEAELFIQATHSLISIKHLMELPDAKTSSREAMPLITQ DPRYEPLKRHRGFIKAWEYIEDFFRMLIGKLTGQDEYEYSKRPCFFKTRSHRLLEEADTMLHSMAPTSS |
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| Nucleotide Sequence: 3360 bp [Download] |
| >gi|54295983|ref|NC_006368.1|:3230473-3233832 Legionella pneumophila str. Paris, complete genome ATGAACGAAATCATACTGCACTTAATGAATGAAATCTCTGCCTTGACTCCACCAATTAACCCCTTAAATT TAAAGCAAATATTTAGTTCAACCCTACTGCCGGAAGGAAAAGCTCCTGTCGAAGTTGAATCCCAATTAAA TCTTTTATTGTTAATTAAAAAACATGTTGATGAATATTCCAGTTTAGCTGAAGAACAAGATGAGTATAAA AGGAAAAAACAAAAACAAGATGAGGTCATGAAAAAAGGAGAAGAACTGCAAAGAAAAATTTCTGATTTGG CTAAAAAAATCGAACTCGCAAAAAGTGAATTAAATCCTTTATACAAAGAAATCGAACCTAAAGCGAACGA AGTCCTGTCCAAACAAAATCCATTAGCACCTCCTTATAAATTCCCTGAATATGGAGAGGTTCAAAAATCA ATTGTTGTCGGGCACTACAGTTATCTCTTCAAAACCAGCAAGGAAATAGAAACGACGCGTGCCAAATTAA AGCTGGTTTTGCTCAAAAATAAATGGCATGCCTTAATGACAGATTTGTCTCAGTTGGGCATTCAACCACC TGTGGAAGAAGATGCTGTTGATAGTTTACAAAAATTTACAGCTGCAGTTGAACTGGAAATTAAAAAATTA ACTCGCTCTTGCGAAAAATGGGATGAATTGCAAAAGCGATTCGCCAAGCAATTATCTGCAACTGATATTA ATAAAAAAGAGACTGAGCTAGAAAAACAAATTGAACTATTGCTTAAAGACCTGGGTCGTATTGAAGCTAC AGTGACTAACCACTCCCTGGTACCCGATTTAAAAGCAGAGTTAATCAGGAAATTTCAAGAAAGTGAAGAC CCTCAAGGATTGATACAGGAATACCAAAATCAGATTGATGGAATATTATCTAATTTTAACCCATCTTCCT GGCTTTCATGGTATTCGGACTCAAGTTATTCTGATAAGCAGCAAAAACTTAAGGACTCAGTTAGCTTCCT GCAATTATTAGCTCAACAAAAAGAGCTAAAAATCAAACATCATGAGCTTGTGAAACAGCAAGAATTGTTG ATTAAAGCGATACCAGAAACTCGTTCAAATGAAGAGGATATATCTATTTATAAGAAGTTAGTTCCTGATG CCATTGATCTGATAAATGAAATACCAATACAAAGTATACCAAATTTTGTTTTACCAAGTGGCCTTTCTTA TGACTCTTCACCTGCAGATTTTTATTTGGTACTTCTCATTCTCATGCCCAAAGTTTCGGAAAAGAAGGAA CAATATTCACAAGCGTTGGAAAAACTTCAAGAAATGCCTGCTCTAGGCAAACAAATACACCAATTAAGAA GTGGATATGATTTACCTGCAACGATGGATGTACAACTTCCAAGTTTGCAAGAAGCTGAAGAAAATAAAGA TACCTTGAATACAGAGGATCCTCTCAAAGAAGAGTTACAAAGCCAGATTAAACTATGCCAATCTTATCTT GAAACAGCCAAGCAAATTGATTTGCTTATGAAAAATCATGGACAAACAACCAATGAAGCAAAAGCACTTA TTGAGCAATTGCGTTTGATTTCAAATCAACCACTAAAGAACGAAGACATAAACTCTATTAAAGAAGATTT ATCTACACTTGCCAATCAAATCCAATCCCTTGTGTCTGAATTAAATCAATTGCCTTTACCTAATCTGACT GGTGAAAAAATTGATCCTTCATTGGAAAAGCAGGAAATAGCAGTAGACAAAGCAATCCCTATTACTGTGG AATTGATGCACCCTGCCCAAGTTTTTCAGATAGGCAATGATTCTCACCTAGAAAAACGGCAGCAAGACAA TGAAGAAGAAACACCGGTTGTTCTGGAATCATCACGCCCCCATCAAGTAATTCACCAAGAGCCTGAATCT CTCGTCGAACTAGGGCAGATAGACAATGGACACGAAATACCGGTTGTTCTCGAATCAACACACCCTCCTC AAATCATTCATACTGAGTCTGAATCTGCTGGTAAAAAACAGCGTGTAGAAGTAGAGCAAGAGATACCAGT AGTACTGGAATTAACACGGCCCTCATCTATGGTCGAAAAGGATTCCGGAGTTACTGTAGAAAAACTAGAA GTAGCTGAGAGACAAGATACACCAATCGTTCTTGAATCAACACGAAGCACTCCTATGGTTCAGAAAGACT CTGGGCTTTCTGGTGAAAAGCAGCATAAAGAGATAGAGCAAGAAATACCTGCTGTTCCGGAATTAACACT CCGCCCCCAAGTGGTTCAGCAAGGCTCTGAGTCCAGTGAAGAACAACAAGTACCCAACGGACAAGAAACA CTGGCTGTTGTCAAATCAAGCCCATCGGAACCATTGAGACCATCAACCCCTGAGGTTCCAGTTATATCCA GGAAACCAAATGGCTTGTCATTATTCAATGGTCACGATGAATTATCAGAAGATAATATTTTAGCCTTTTT TGATGAGGCTGGTAATCAAATTACTATCTCATCTGAAGAAGATTCCGAGACGCTTGCCATAGACAGAGGA AAAGTAAATTCTTTAGGAATTGATAAAGCATTTAAAGAAGAACCGGTTTCTACAGGCCATGAGTTAGATA AATTATCAAATCCTCAACACCAGGAATCTGCTCCTAACATCTCCCCTTTGCCACCATCTTCTATCCTGCT TAAGCAAAAATTAGATTCATTTCATGTACAAAACATGGAATATATAAAGCAACAATCAGAAGAAATACAG CTATGGTATAAAGGTTTATATGATGCAGCGCAAAGTTCTTGTTTAAATGAGGCATTGGGTCTTAAAGCAC TTCATCTTTTCAAAGACATCTTGTTTGAATTAAAAAATCAAAATGATTTATCTGTATTACTGGCATACAA GCGCATGTGCCCAAACCCATTACAAGATATACAAAATATTCTCCGTTTAAAACCTGCTTTGCCTATACTT GATGAATCGATTGATGAAGAACAGCAGTTAAAGAATTGGCCTGAAGAATTGCAAAAATTTCATCAGCAAT ATGTAAAATTGAAAAAGGAACATCCATTGGAAGCTGAATTATTTATTCAGGCAACTCATTCTCTTATTTC AATTAAACATTTGATGGAACTCCCTGATGCAAAAACTTCAAGCCGAGAAGCCATGCCTCTCATTACTCAA GATCCCCGATATGAGCCTTTAAAACGGCATAGAGGATTTATAAAAGCATGGGAATATATTGAAGATTTTT TCCGAATGTTAATAGGTAAGTTAACAGGGCAAGATGAATATGAGTATTCAAAAAGGCCTTGTTTTTTCAA AACAAGATCTCACCGATTACTTGAAGAGGCTGACACAATGCTCCACTCCATGGCTCCAACAAGCAGTTAA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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| in silico analysis literature |