| Effector Protein ID: 54297904 |
 T4SS name [ID] | Dot/Icm [40] |
| Gene symbol | - |
| Locus tag | lpp1959 |
| Strain | Legionella pneumophila str. Paris |
| Replicon | chromosome [GenBank: NC_006368] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 2218765..2220192 [+] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | PieG/legG1 |
| T4CP requirement | T4CP Depedent |
| Target/Effection | LegG1 has an RCC1 domain which can act as a guanine-nucleotide dissociation stimulator for the Ran GTP-binding protein (de Felipe, et al. 2005) |
| UniProt ID | Q5X3S5 |
| KEGG ID | lpp:lpp1959 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | RCC1 [PF00415], Evalue: 8.9e-27, Aligned region: 250..278 RCC1 [PF00415], Evalue: 8.9e-27, Aligned region: 307..352 RCC1 [PF00415], Evalue: 8.9e-27, Aligned region: 364..408 |
| Protein Sequence: 475 a.a. [Download] |
| >gi|54297904|ref|YP_124273.1| hypothetical protein lpp1959 [Legionella pneumophila str. Paris] MPDVSGKPDANQIPDDVWLDILINYLQPQDAVNLSEVNNRLNRLFATQHTQSEQLHRKKTLGILKVFTGY SSTFLFIRFNGKQRLFRAMDSNSITPLLMPISLPENVSYIESIQSTYKHTVVVGRDNRDQIIVATNKIHK DYSRQETSHNQLIPLPLRNNNISLVSVGNNEESYIFNPIFLLSRNAAGQLSLQLHKINSKAPLETTIEDR DCQLPIPLPDTFKTVTKISSGVWHTVIAGYDQHNRPQIATFGKNCDGQLGTGDWENRDTPTQAKLPPEMH TLHTIQTRFFHTIATGLDKNGYPIVASCGYNSDGQLGCGDKDNKNALIPIKLPENMKSVEMVATGVKHTV IVGKDINNKPMVATCGHNGYGQLGTGDEENRLYLTLIGIPEDITTVDYIEAGTYHTVICGRNMKNQPTLA LCGCNSDGELGLAPQKITQKSSLMTNPALFFPPRQDRNAINNMMKISTFSPCNLL |
| - |
| Nucleotide Sequence: 1428 bp [Download] |
| >gi|54295983|ref|NC_006368.1|:2218765-2220192 Legionella pneumophila str. Paris, complete genome ATGCCTGATGTTAGCGGCAAACCTGATGCAAACCAGATTCCAGATGACGTCTGGCTTGACATTCTTATCA ATTATCTTCAACCACAGGATGCTGTGAACCTGTCTGAAGTCAACAATCGCCTGAACCGACTTTTCGCAAC TCAACATACTCAATCTGAGCAATTGCACCGAAAAAAAACATTAGGAATTCTGAAGGTATTTACAGGATAT AGTTCCACCTTCCTGTTTATACGCTTCAATGGCAAACAAAGATTATTTAGAGCAATGGATAGCAATAGCA TAACCCCACTATTAATGCCCATCTCTTTGCCAGAGAACGTCTCTTATATTGAATCCATTCAATCAACATA CAAACACACTGTTGTTGTTGGTCGTGATAATCGCGATCAAATTATAGTGGCAACAAATAAAATCCATAAG GATTATTCAAGGCAAGAAACCAGCCACAATCAGCTGATTCCCCTTCCATTACGCAATAATAACATTTCTC TGGTATCTGTCGGGAATAATGAAGAGAGCTATATTTTTAACCCTATTTTTCTCTTATCCCGCAATGCAGC AGGGCAATTGAGTCTTCAATTACATAAAATAAATAGCAAGGCTCCATTGGAAACCACAATTGAGGATAGA GACTGCCAGTTGCCCATCCCATTGCCTGACACGTTCAAAACAGTAACAAAAATAAGCTCAGGGGTGTGGC ATACCGTCATTGCAGGCTATGATCAGCACAACCGACCTCAAATTGCTACCTTTGGAAAAAACTGCGATGG TCAATTAGGTACAGGGGATTGGGAAAACCGAGATACTCCCACCCAGGCAAAGCTTCCCCCTGAAATGCAT ACACTCCATACAATCCAAACCAGATTTTTTCACACCATTGCCACTGGGCTTGATAAAAATGGATACCCTA TCGTTGCAAGCTGCGGTTATAACTCCGATGGCCAATTGGGATGCGGGGATAAAGATAATAAAAACGCATT GATTCCCATCAAACTTCCAGAAAATATGAAATCAGTAGAAATGGTCGCCACTGGAGTAAAACACACCGTT ATTGTGGGAAAAGACATAAATAACAAGCCTATGGTTGCAACCTGTGGGCATAACGGCTATGGACAGCTGG GTACAGGCGATGAAGAGAACCGCCTCTACTTAACCCTCATCGGGATTCCCGAGGATATTACAACTGTCGA TTATATTGAAGCAGGCACCTATCATACTGTTATTTGTGGGCGGAACATGAAAAATCAGCCGACTCTTGCT TTATGTGGGTGTAATTCAGACGGTGAATTGGGACTTGCTCCACAAAAAATCACCCAAAAATCATCCCTGA TGACCAACCCAGCCCTGTTCTTTCCGCCGAGACAAGACAGGAACGCAATAAACAATATGATGAAAATTAG TACATTCTCGCCATGTAATTTGCTATGA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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| in silico analysis literature |