T4SS ID	397
Strain	Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044
Replicon	chromosome [Browse all T4SS(s) in this replicon]
Accession	NC_012731
Location	3449935..3462792
Name	VirB
Function	conjugation
Classification	Type IVA; Type P
Experimental investigation has been performed on this T4SS.

T4SS components

Component	VirB1	VirB2	VirB3	VirB4	VirB5	VirB6	VirB7	VirB8	VirB9
Number	1	1	0	1	1	1	0	1	1
Component	VirB10	VirB11	VirD4
Number	1	1	1

The information of T4SS components from NC_012731
#	Locus tag (Gene)	Coordinates [+/-], size (bp)	Protein GI	Product	Component
1	KP1_RS28005	3445615..3445812 [-], 198	1148293491	small membrane protein
2	KP1_RS16895 (rmpA)	3445784..3446416 [-], 633	506355267	mucoid phenotype A regulator RmpA
3	KP1_RS16900	3446958..3447611 [+], 654	506355269	class I SAM-dependent methyltransferase
4	KP1_RS28885	3447691..3448181 [-], 491	pseudogene	IS3 family transposase
5	KP1_RS28015 (istB)	3448249..3448464 [-], 216	pseudogene	IS21-like element IS100kyp family helper ATPase IstB
6	KP1_RS16915	3448919..3449152 [+], 234	447153915	hypothetical protein
7	KP1_RS16920	3449225..3449935 [+], 711	506355271	lytic transglycosylase domain-containing protein	VirB1
8	KP1_RS16925	3449935..3450228 [+], 294	446522825	TrbC/VirB2 family protein	VirB2
9	KP1_RS16930	3450241..3452979 [+], 2739	506355272	VirB3 family type IV secretion system protein	VirB4
10	KP1_RS16935	3452997..3453701 [+], 705	506355273	type IV secretion system protein	VirB5
11	KP1_RS28020	3453711..3453938 [+], 228	490282214	EexN family lipoprotein
12	KP1_RS16940	3453950..3455029 [+], 1080	506355274	type IV secretion system protein	VirB6
13	KP1_RS16950	3455245..3455928 [+], 684	506355275	type IV secretion system protein	VirB8
14	KP1_RS16955 (virB9)	3455925..3456833 [+], 909	506355276	P-type conjugative transfer protein VirB9	VirB9
15	KP1_RS16960	3456877..3458127 [+], 1251	506355277	TrbI/VirB10 family protein	VirB10
16	KP1_RS16965 (virB11)	3458117..3459142 [+], 1026	506355278	P-type DNA transfer ATPase VirB11	VirB11
17	KP1_RS28025	3459139..3459537 [+], 399	506355279	cag pathogenicity island Cag12 family protein
18	KP1_RS28030	3459573..3459875 [+], 303	506355280	hypothetical protein
19	KP1_RS16970	3459918..3460223 [+], 306	506355281	hypothetical protein
20	KP1_RS16975	3460933..3462792 [+], 1860	694104762	TraM recognition domain-containing protein
21	KP1_RS16980	3462802..3463548 [+], 747	506355284	hypothetical protein
22	KP1_RS16985	3463744..3464691 [-], 948	506355285	DUF1738 domain-containing protein
23	KP1_RS16990	3465676..3466491 [-], 816	506355286	hypothetical protein

Genes in the 5-Kb flanking regions if available, or non-essential genes in the T4SS gene cluster if any.

Download FASTA format files

Proteins        Genes

This T4SS is encoded by the integrative and conjugative element (ICE) ICEKp1 and is thought to contribute to the transfer of this element. (click on the ICE name to view the detail ICE informaion in ICEberg, an ICE database)

(1) Lin TL et al. (2008). Characterization of integrative and conjugative element ICEKp1-associated genomic heterogeneity in a Klebsiella pneumoniae strain isolated from a primary liver abscess. J Bacteriol. 190(2):515-26. [PudMed:17981959]

This literature contains experimental investigation