Detailed information NTG0999142

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: ABD426_RS03375
• Genome accession: NZ_CP155739
• Coordinates: 637393..638259 (+)
• Length: 288 a.a.
• NCBI ID: WP_023612376.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain 997/08
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 632393..643259

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABD426_RS03345 (ABD426_03330)	-	632434..633309 (+)	876	WP_002985236.1	F0F1 ATP synthase subunit gamma	-
ABD426_RS03350 (ABD426_03335)	atpD	633471..634877 (+)	1407	WP_002985235.1	F0F1 ATP synthase subunit beta	-
ABD426_RS03355 (ABD426_03340)	-	634890..635306 (+)	417	WP_002985233.1	F0F1 ATP synthase subunit epsilon	-
ABD426_RS03360 (ABD426_03345)	-	635593..635829 (+)	237	WP_009881177.1	DUF1146 family protein	-
ABD426_RS03365 (ABD426_03350)	murA	635894..637165 (+)	1272	WP_002990414.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
ABD426_RS03370 (ABD426_03355)	-	637169..637357 (+)	189	WP_011017613.1	DNA-directed RNA polymerase subunit beta	-
ABD426_RS03375 (ABD426_03360)	endA	637393..638259 (+)	867	WP_023612376.1	DNA/RNA non-specific endonuclease	Machinery gene
ABD426_RS03380 (ABD426_03365)	pheS	638542..639585 (+)	1044	WP_003057440.1	phenylalanine--tRNA ligase subunit alpha	-
ABD426_RS03385 (ABD426_03370)	pheT	639795..642200 (+)	2406	WP_032465590.1	phenylalanine--tRNA ligase subunit beta	-
ABD426_RS03390 (ABD426_03375)	-	642310..642687 (+)	378	WP_002993028.1	OsmC family protein	-
ABD426_RS03395 (ABD426_03380)	-	642680..643066 (+)	387	WP_002990406.1	YbgA family protein	-

Sequence

Protein

• Length: 288 a.a.
• Molecular weight: 32087.59 Da
• Isoelectric Point: 10.5080

>NTDB_id=999142 ABD426_RS03375 WP_023612376.1 637393..638259(+) (endA) [Streptococcus pyogenes strain 997/08]
MLAKKKRKRVLNSFLLILLVLGSNCLAKSDFIASNHPIKQLYQTLVGEKKKSLLTHNNLPADVPTEALAASVLTPSIKKQ
LGPDVQWNGAGAYIINRNKTDLNAKVASLPYANNETKWVQEQKVPKRANALLTKSTRQYRNRYQTDNAYRNFKPAGWHRL
HHLKGSYDHAVDRGHLLGYALVGGLKGLDASTGNPDNIATQLSWANQANKPYSTGQNYYEGLVRRALDKGHRVRYRVTLL
YDGDNLLASGSHLEAKSSDGSLTFNVFVPNVQPGLTVDYRTRQIAINL

Nucleotide

• Length: 867 bp

>NTDB_id=999142 ABD426_RS03375 WP_023612376.1 637393..638259(+) (endA) [Streptococcus pyogenes strain 997/08]
ATGTTAGCAAAGAAAAAACGAAAAAGGGTGCTTAATTCCTTCTTATTGATTTTGTTAGTGTTGGGGTCTAACTGCCTTGC
TAAGAGTGATTTCATAGCTAGCAATCACCCTATCAAGCAACTTTATCAGACTCTTGTTGGGGAGAAGAAAAAATCATTAC
TCACACATAATAATTTGCCCGCTGATGTTCCCACAGAAGCTCTGGCGGCATCGGTATTAACACCATCAATCAAAAAGCAA
CTAGGTCCAGATGTTCAGTGGAATGGAGCAGGCGCCTATATTATCAACAGGAACAAAACAGATTTAAATGCTAAGGTAGC
CAGTCTGCCCTATGCCAACAATGAAACCAAATGGGTGCAAGAGCAAAAGGTTCCTAAAAGAGCTAATGCCTTACTTACTA
AGTCGACACGACAGTATCGAAATCGCTATCAAACGGACAATGCTTATCGTAACTTTAAGCCAGCAGGTTGGCACCGATTG
CACCACTTAAAAGGAAGTTATGATCACGCGGTTGATAGAGGGCATTTGCTAGGTTATGCTTTAGTTGGTGGACTGAAAGG
TTTAGATGCTTCTACCGGTAATCCTGATAATATTGCCACTCAACTAAGTTGGGCTAATCAAGCAAATAAACCCTACTCGA
CAGGTCAGAATTACTATGAAGGTTTAGTACGTCGTGCTTTAGATAAGGGGCATCGCGTCCGCTACCGTGTCACCCTACTT
TATGATGGTGATAATCTACTAGCCAGTGGTAGCCATTTGGAGGCTAAATCCTCTGATGGCAGCTTGACTTTTAACGTGTT
TGTTCCAAATGTCCAACCAGGATTGACCGTTGATTATAGGACGAGACAAATAGCTATCAATCTCTAA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (111-246)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	58.65	82.292	0.483
endA	Streptococcus pneumoniae D39	58.65	82.292	0.483
endA	Streptococcus pneumoniae R6	58.65	82.292	0.483
endA	Streptococcus pneumoniae TIGR4	58.65	82.292	0.483