Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   ABD411_RS03080 Genome accession   NZ_CP155734
Coordinates   594710..595576 (+) Length   288 a.a.
NCBI ID   WP_023612376.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 8373/17     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 589710..600576
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABD411_RS03050 (ABD411_03035) - 589751..590626 (+) 876 WP_002985236.1 F0F1 ATP synthase subunit gamma -
  ABD411_RS03055 (ABD411_03040) atpD 590788..592194 (+) 1407 WP_002985235.1 F0F1 ATP synthase subunit beta -
  ABD411_RS03060 (ABD411_03045) - 592207..592623 (+) 417 WP_002985233.1 F0F1 ATP synthase subunit epsilon -
  ABD411_RS03065 (ABD411_03050) - 592910..593146 (+) 237 WP_009881177.1 DUF1146 family protein -
  ABD411_RS03070 (ABD411_03055) murA 593211..594482 (+) 1272 WP_002990414.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  ABD411_RS03075 (ABD411_03060) - 594486..594674 (+) 189 WP_011017613.1 DNA-directed RNA polymerase subunit beta -
  ABD411_RS03080 (ABD411_03065) endA 594710..595576 (+) 867 WP_023612376.1 DNA/RNA non-specific endonuclease Machinery gene
  ABD411_RS03085 (ABD411_03070) pheS 595859..596902 (+) 1044 WP_003057440.1 phenylalanine--tRNA ligase subunit alpha -
  ABD411_RS03090 (ABD411_03075) pheT 597112..599517 (+) 2406 WP_032465590.1 phenylalanine--tRNA ligase subunit beta -

Sequence

Protein


Download         Length: 288 a.a.        Molecular weight: 32087.59 Da        Isoelectric Point: 10.5080

>NTDB_id=998850 ABD411_RS03080 WP_023612376.1 594710..595576(+) (endA) [Streptococcus pyogenes strain 8373/17]
MLAKKKRKRVLNSFLLILLVLGSNCLAKSDFIASNHPIKQLYQTLVGEKKKSLLTHNNLPADVPTEALAASVLTPSIKKQ
LGPDVQWNGAGAYIINRNKTDLNAKVASLPYANNETKWVQEQKVPKRANALLTKSTRQYRNRYQTDNAYRNFKPAGWHRL
HHLKGSYDHAVDRGHLLGYALVGGLKGLDASTGNPDNIATQLSWANQANKPYSTGQNYYEGLVRRALDKGHRVRYRVTLL
YDGDNLLASGSHLEAKSSDGSLTFNVFVPNVQPGLTVDYRTRQIAINL

Nucleotide


Download         Length: 867 bp        

>NTDB_id=998850 ABD411_RS03080 WP_023612376.1 594710..595576(+) (endA) [Streptococcus pyogenes strain 8373/17]
ATGTTAGCAAAGAAAAAACGAAAAAGGGTGCTTAATTCCTTCTTATTGATTTTGTTAGTGTTGGGGTCTAACTGCCTTGC
TAAGAGTGATTTCATAGCTAGCAATCACCCTATCAAGCAACTTTATCAGACTCTTGTTGGGGAGAAGAAAAAATCATTAC
TCACACATAATAATTTGCCCGCTGATGTTCCCACAGAAGCTCTGGCGGCATCGGTATTAACACCATCAATCAAAAAGCAA
CTAGGTCCAGATGTTCAGTGGAATGGAGCAGGCGCCTATATTATCAACAGGAACAAAACAGATTTAAATGCTAAGGTAGC
CAGTCTGCCCTATGCCAACAATGAAACCAAATGGGTGCAAGAGCAAAAGGTTCCTAAAAGAGCTAATGCCTTACTTACTA
AGTCGACACGACAGTATCGAAATCGCTATCAAACGGACAATGCTTATCGTAACTTTAAGCCAGCAGGTTGGCACCGATTG
CACCACTTAAAAGGAAGTTATGATCACGCGGTTGATAGAGGGCATTTGCTAGGTTATGCTTTAGTTGGTGGACTGAAAGG
TTTAGATGCTTCTACCGGTAATCCTGATAATATTGCCACTCAACTAAGTTGGGCTAATCAAGCAAATAAACCCTACTCGA
CAGGTCAGAATTACTATGAAGGTTTAGTACGTCGTGCTTTAGATAAGGGGCATCGCGTCCGCTACCGTGTCACCCTACTT
TATGATGGTGATAATCTACTAGCCAGTGGTAGCCATTTGGAGGCTAAATCCTCTGATGGCAGCTTGACTTTTAACGTGTT
TGTTCCAAATGTCCAACCAGGATTGACCGTTGATTATAGGACGAGACAAATAGCTATCAATCTCTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(111-246)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

58.65

82.292

0.483
  endA Streptococcus pneumoniae D39

58.65

82.292

0.483
  endA Streptococcus pneumoniae R6

58.65

82.292

0.483
  endA Streptococcus pneumoniae TIGR4

58.65

82.292

0.483

Multiple sequence alignment