NTDB

Overview

Name	codY	Type	Regulator
Locus tag	ELZ51_RS09155	Genome accession	NZ_LR134094
Coordinates	1817258..1818040 (-)	Length	260 a.a.
NCBI ID	WP_003053880.1	Uniprot ID	A0A9X9SKT8
Organism	Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669
Function	repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1812258..1823040

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ELZ51_RS09125 (NCTC4669_01925)	-	1812911..1813504 (-)	594	WP_274047907.1	helix-turn-helix transcriptional regulator	-
ELZ51_RS09130 (NCTC4669_01926)	-	1813735..1814034 (-)	300	WP_126427150.1	rhodanese-like domain-containing protein	-
ELZ51_RS09135 (NCTC4669_01927)	-	1814027..1815679 (-)	1653	WP_126427152.1	FAD-dependent oxidoreductase	-
ELZ51_RS09140 (NCTC4669_01928)	-	1815689..1816027 (-)	339	WP_003052556.1	rhodanese-like domain-containing protein	-
ELZ51_RS09145 (NCTC4669_01929)	-	1816240..1816500 (+)	261	WP_126427154.1	metal-sensitive transcriptional regulator	-
ELZ51_RS09150 (NCTC4669_01930)	-	1816567..1817118 (-)	552	WP_197715869.1	cysteine hydrolase family protein	-
ELZ51_RS09155 (NCTC4669_01931)	codY	1817258..1818040 (-)	783	WP_003053880.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
ELZ51_RS09160 (NCTC4669_01932)	-	1818306..1819520 (-)	1215	WP_126427158.1	pyridoxal phosphate-dependent aminotransferase	-
ELZ51_RS09165 (NCTC4669_01933)	-	1819856..1820308 (+)	453	WP_003052566.1	universal stress protein	-
ELZ51_RS09170 (NCTC4669_01934)	-	1820471..1821859 (-)	1389	WP_003052568.1	Cof-type HAD-IIB family hydrolase	-
ELZ51_RS09175 (NCTC4669_01935)	-	1822249..1822746 (-)	498	WP_003052572.1	staphylokinase domain-containing protein	-

Sequence

Protein

Download Length: 260 a.a. Molecular weight: 28748.89 Da Isoelectric Point: 4.4678

                                >NTDB_id=997769 ELZ51_RS09155 WP_003053880.1 1817258..1818040(-) (codY) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]

MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV

KAASRVYDTEANLSVESELTIFPVESKDIYPDGLTTIAPIYGGGMRLGSLIIWRNDNEFSDEDLILVEISSTVVGIQLLN

LQTENLEETIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG

MKGTYLKVINEGIFDKLKEF

Nucleotide

Download Length: 783 bp

                                >NTDB_id=997769 ELZ51_RS09155 WP_003053880.1 1817258..1818040(-) (codY) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]

ATGCCTAACTTATTAGAAAAAACTCGTAAAATTACGTCTATTCTACAGCGCTCTGTAGATAGCTTGGAGACAGAACTCCC

TTATAATACGATGGCGTCTCGCTTGGCAGATATTATTGACTGTAATGCCTGCATTATCAATGGCGGAGGAACCCTACTTG

GTTATGCCATGAAATATAAAACCAACACAGATCGTGTTGAGGAATTTTTTGAAGCTAAGCAATTTCCAGATACTTATGTC

AAAGCAGCTAGCCGTGTCTACGACACTGAGGCCAATCTTTCAGTGGAAAGTGAATTAACCATTTTTCCTGTGGAATCGAA

AGACATCTATCCAGATGGTTTGACAACAATTGCACCGATTTATGGTGGAGGTATGCGTCTAGGATCTCTTATCATTTGGC

GCAACGATAATGAGTTTAGTGATGAGGACCTCATCTTGGTTGAAATTTCAAGCACGGTTGTTGGGATTCAGTTGTTAAAC

CTTCAAACAGAAAACTTGGAAGAAACGATCCGTAAGCAAACTGCTGTCAACATGGCTATTAACACCCTATCTTATTCAGA

AATGAAGGCTGTTGCAGCTATTCTTGGTGAATTGGATGGTAACGAAGGCCGTTTAACAGCTTCTGTCATTGCTGACCGTA

TTGGCATTACACGATCTGTGATCGTCAATGCCCTTCGTAAATTGGAAAGTGCTGGTATTATTGAAAGTCGCTCTCTGGGC

ATGAAGGGAACCTACCTCAAGGTTATTAATGAGGGAATTTTTGATAAATTGAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A9X9SKT8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	66.537	98.846	0.658
codY	Bacillus subtilis subsp. subtilis str. 168	53.036	95	0.504

Detailed information NTG0997769