Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   KZZ19_RS18610 Genome accession   NZ_CP155559
Coordinates   3619756..3620535 (-) Length   259 a.a.
NCBI ID   WP_000421290.1    Uniprot ID   A0A9W5VKA1
Organism   Bacillus thuringiensis strain HSY204     
Function   repression of comK (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 3594453..3656262 3619756..3620535 within 0


Gene organization within MGE regions


Location: 3594453..3656262
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KZZ19_RS18500 (KZZ19_018495) - 3595023..3595922 (-) 900 WP_237979326.1 polysaccharide deacetylase family protein -
  KZZ19_RS18505 (KZZ19_018500) pnp 3596075..3598213 (-) 2139 WP_046957398.1 polyribonucleotide nucleotidyltransferase -
  KZZ19_RS18510 (KZZ19_018505) rpsO 3598374..3598643 (-) 270 WP_001229392.1 30S ribosomal protein S15 -
  KZZ19_RS18515 (KZZ19_018510) ribF 3598744..3599715 (-) 972 WP_088097483.1 bifunctional riboflavin kinase/FAD synthetase -
  KZZ19_RS18520 (KZZ19_018515) truB 3599759..3600682 (-) 924 WP_237979327.1 tRNA pseudouridine(55) synthase TruB -
  KZZ19_RS18525 (KZZ19_018520) rbfA 3600769..3601125 (-) 357 WP_000776445.1 30S ribosome-binding factor RbfA -
  KZZ19_RS18530 (KZZ19_018525) - 3601141..3601422 (-) 282 WP_000582364.1 DUF503 family protein -
  KZZ19_RS18535 (KZZ19_018530) infB 3601419..3603485 (-) 2067 WP_237979328.1 translation initiation factor IF-2 -
  KZZ19_RS18540 (KZZ19_018535) - 3603490..3603801 (-) 312 WP_001286527.1 YlxQ family RNA-binding protein -
  KZZ19_RS18545 (KZZ19_018540) - 3603802..3604074 (-) 273 WP_000071127.1 YlxR family protein -
  KZZ19_RS18550 (KZZ19_018545) nusA 3604086..3605192 (-) 1107 WP_000102596.1 transcription termination factor NusA -
  KZZ19_RS18555 (KZZ19_018550) rimP 3605210..3605680 (-) 471 WP_000359098.1 ribosome maturation factor RimP -
  KZZ19_RS18560 (KZZ19_018555) - 3606015..3610316 (-) 4302 WP_237979329.1 PolC-type DNA polymerase III -
  KZZ19_RS18565 (KZZ19_018560) - 3610441..3612141 (-) 1701 WP_237979330.1 proline--tRNA ligase -
  KZZ19_RS18570 (KZZ19_018565) rseP 3612252..3613508 (-) 1257 WP_237979331.1 RIP metalloprotease RseP -
  KZZ19_RS18575 (KZZ19_018570) dxr 3613526..3614668 (-) 1143 WP_088097489.1 1-deoxy-D-xylulose-5-phosphate reductoisomerase -
  KZZ19_RS18580 (KZZ19_018575) cdsA 3614692..3615483 (-) 792 WP_088097490.1 phosphatidate cytidylyltransferase -
  KZZ19_RS18585 (KZZ19_018580) uppS 3615501..3616277 (-) 777 WP_000971311.1 isoprenyl transferase -
  KZZ19_RS18590 (KZZ19_018585) frr 3616363..3616920 (-) 558 WP_000531506.1 ribosome recycling factor -
  KZZ19_RS18595 (KZZ19_018590) pyrH 3616923..3617645 (-) 723 WP_000042667.1 UMP kinase -
  KZZ19_RS18600 (KZZ19_018595) tsf 3617712..3618599 (-) 888 WP_088097491.1 translation elongation factor Ts -
  KZZ19_RS18605 (KZZ19_018600) rpsB 3618703..3619404 (-) 702 WP_000111484.1 30S ribosomal protein S2 -
  KZZ19_RS18610 (KZZ19_018605) codY 3619756..3620535 (-) 780 WP_000421290.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  KZZ19_RS18615 (KZZ19_018610) hslU 3620613..3622004 (-) 1392 WP_237979332.1 ATP-dependent protease ATPase subunit HslU -
  KZZ19_RS18620 (KZZ19_018615) hslV 3622027..3622569 (-) 543 WP_000526271.1 ATP-dependent protease proteolytic subunit HslV -
  KZZ19_RS18625 (KZZ19_018620) xerC 3622612..3623511 (-) 900 WP_237979333.1 tyrosine recombinase XerC -
  KZZ19_RS18630 (KZZ19_018625) trmFO 3623577..3624881 (-) 1305 WP_000211996.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  KZZ19_RS18635 (KZZ19_018630) topA 3624930..3627008 (-) 2079 WP_001286953.1 type I DNA topoisomerase -
  KZZ19_RS18640 (KZZ19_018635) dprA 3627153..3628022 (-) 870 WP_237979334.1 DNA-processing protein DprA -
  KZZ19_RS18645 (KZZ19_018640) sucD 3628110..3629012 (-) 903 WP_000115178.1 succinate--CoA ligase subunit alpha -
  KZZ19_RS18650 (KZZ19_018645) sucC 3629032..3630192 (-) 1161 WP_076539696.1 ADP-forming succinate--CoA ligase subunit beta -
  KZZ19_RS18655 (KZZ19_018650) - 3630387..3631160 (-) 774 WP_098341880.1 ribonuclease HII -
  KZZ19_RS18660 (KZZ19_018655) ylqF 3631213..3632103 (-) 891 WP_098341879.1 ribosome biogenesis GTPase YlqF -
  KZZ19_RS18665 (KZZ19_018660) lepB 3632124..3632675 (-) 552 WP_000711857.1 signal peptidase I -
  KZZ19_RS18670 (KZZ19_018665) rplS 3632777..3633121 (-) 345 WP_001186518.1 50S ribosomal protein L19 -
  KZZ19_RS18675 (KZZ19_018670) trmD 3633268..3634002 (-) 735 WP_064475006.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  KZZ19_RS18680 (KZZ19_018675) rimM 3634002..3634517 (-) 516 WP_048546010.1 ribosome maturation factor RimM -
  KZZ19_RS18685 (KZZ19_018680) - 3634639..3634866 (-) 228 WP_016118543.1 KH domain-containing protein -
  KZZ19_RS18690 (KZZ19_018685) rpsP 3634881..3635153 (-) 273 WP_000268750.1 30S ribosomal protein S16 -
  KZZ19_RS18695 (KZZ19_018690) ffh 3635254..3636603 (-) 1350 WP_237979336.1 signal recognition particle protein -
  KZZ19_RS18700 (KZZ19_018695) - 3636616..3636948 (-) 333 WP_000891061.1 putative DNA-binding protein -
  KZZ19_RS18705 (KZZ19_018700) ftsY 3637082..3638071 (-) 990 WP_088097495.1 signal recognition particle-docking protein FtsY -
  KZZ19_RS18710 (KZZ19_018705) smc 3638087..3641656 (-) 3570 WP_237979338.1 chromosome segregation protein SMC -
  KZZ19_RS18715 (KZZ19_018710) rncS 3641804..3642541 (-) 738 WP_098341877.1 ribonuclease III -
  KZZ19_RS18720 (KZZ19_018715) acpP 3642600..3642833 (-) 234 WP_000786062.1 acyl carrier protein -
  KZZ19_RS18725 (KZZ19_018720) fabG 3642903..3643643 (-) 741 WP_061678211.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  KZZ19_RS18730 (KZZ19_018725) fabD 3643643..3644587 (-) 945 WP_237979340.1 ACP S-malonyltransferase -
  KZZ19_RS18735 (KZZ19_018730) plsX 3644602..3645594 (-) 993 WP_237979343.1 phosphate acyltransferase PlsX -
  KZZ19_RS18740 (KZZ19_018735) fapR 3645591..3646184 (-) 594 WP_000747352.1 transcription factor FapR -
  KZZ19_RS18745 (KZZ19_018740) recG 3646273..3648321 (-) 2049 WP_088097500.1 ATP-dependent DNA helicase RecG -
  KZZ19_RS18750 (KZZ19_018745) - 3648605..3650281 (-) 1677 WP_237979345.1 DAK2 domain-containing protein -
  KZZ19_RS18755 (KZZ19_018750) - 3650304..3650666 (-) 363 WP_000021109.1 Asp23/Gls24 family envelope stress response protein -
  KZZ19_RS18760 (KZZ19_018755) rpmB 3651043..3651231 (+) 189 WP_000124776.1 50S ribosomal protein L28 -
  KZZ19_RS18765 (KZZ19_018760) spoVM 3651305..3651385 (-) 81 WP_001213599.1 stage V sporulation protein SpoVM -
  KZZ19_RS18770 (KZZ19_018765) - 3651452..3652132 (-) 681 WP_140392533.1 thiamine diphosphokinase -
  KZZ19_RS18775 (KZZ19_018770) rpe 3652232..3652876 (-) 645 WP_076539726.1 ribulose-phosphate 3-epimerase -
  KZZ19_RS18780 (KZZ19_018775) rsgA 3652879..3653760 (-) 882 WP_237979346.1 ribosome small subunit-dependent GTPase A -
  KZZ19_RS18785 (KZZ19_018780) prkC 3654029..3656002 (-) 1974 WP_237979347.1 serine/threonine protein kinase PrkC -

Sequence

Protein


Download         Length: 259 a.a.        Molecular weight: 28793.05 Da        Isoelectric Point: 4.7165

>NTDB_id=997756 KZZ19_RS18610 WP_000421290.1 3619756..3620535(-) (codY) [Bacillus thuringiensis strain HSY204]
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLF
NITETSSNLDVNSAYTAFPVENRELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLQELAKLKTN

Nucleotide


Download         Length: 780 bp        

>NTDB_id=997756 KZZ19_RS18610 WP_000421290.1 3619756..3620535(-) (codY) [Bacillus thuringiensis strain HSY204]
ATGGAATTATTAGCAAAAACAAGAAAATTAAATGCGTTATTACAGAGCGCAGCAGGTAAGCCTGTAAACTTTAGAGAGAT
GTCTGACACAATGTGTGAAGTAATCGAAGCGAACGTATTCGTAGTAAGTCGTCGTGGTAAATTACTAGGTTATGCAATTC
ACCAACAAATTGAGAATGAGCGTATGAAACAAATGCTTGCAGAGCGTCAATTCCCGGAAGAATACACGCAAAGCTTATTC
AACATTACAGAAACATCTTCAAACTTAGATGTAAACAGTGCTTACACAGCATTCCCGGTAGAAAATAGAGAATTATTCGG
TCAAGGTTTAACTACAATCGTACCAATCGTTGGTGGTGGTGAGCGTCTAGGTACATTAGTGTTAGCTCGTCTTGGTCAAG
AGTTCTTAGATGATGATTTAATCCTTGCTGAATACAGTTCAACTGTAGTAGGTATGGAAATCTTACGTGAAAAAGCAGAA
GAAATCGAAGAGGAAGCACGTAGTAAAGCTGTTGTTCAAATGGCGATTAGCTCATTATCTTACAGTGAGTTAGAAGCAAT
CGAGCATATCTTCGAAGAATTAAATGGAACAGAAGGTTTACTTGTTGCAAGTAAAATTGCTGATCGCGTAGGAATTACTC
GTTCTGTAATCGTAAATGCACTTCGTAAATTAGAGAGTGCTGGTGTTATTGAGTCTCGCTCTTTAGGTATGAAAGGAACA
TACATTAAAGTGCTAAACGACAAGTTTCTACAGGAACTTGCTAAATTAAAAACAAACTAA

Domains

Predicted by InterproScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

81.467

100

0.815
  codY Lactococcus lactis subsp. lactis strain DGCC12653

46.667

98.456

0.459

Multiple sequence alignment