Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   EW032_RS06175 Genome accession   NZ_LR130509
Coordinates   1220676..1221449 (+) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus strain BPH2760 isolate BPH2760     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1215676..1226449
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW032_RS06155 trmFO 1216020..1217327 (+) 1308 WP_129621158.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  EW032_RS06160 xerC 1217744..1218640 (+) 897 WP_001015602.1 tyrosine recombinase XerC -
  EW032_RS06165 hslV 1218637..1219182 (+) 546 WP_000072681.1 ATP-dependent protease subunit HslV -
  EW032_RS06170 hslU 1219248..1220651 (+) 1404 WP_000379054.1 ATP-dependent protease ATPase subunit HslU -
  EW032_RS06175 codY 1220676..1221449 (+) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  EW032_RS06180 - 1221500..1221592 (+) 93 WP_031788481.1 hypothetical protein -
  EW032_RS06185 rpsB 1221791..1222558 (+) 768 WP_000268484.1 30S ribosomal protein S2 -
  EW032_RS06190 - 1222592..1222705 (+) 114 WP_001789890.1 hypothetical protein -
  EW032_RS06195 tsf 1222740..1223621 (+) 882 WP_000201387.1 translation elongation factor Ts -
  EW032_RS06200 pyrH 1223758..1224480 (+) 723 WP_000057330.1 UMP kinase -
  EW032_RS06205 frr 1224499..1225053 (+) 555 WP_001280006.1 ribosome recycling factor -
  EW032_RS06210 - 1225426..1226196 (+) 771 WP_000473705.1 isoprenyl transferase -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=994597 EW032_RS06175 WP_000055337.1 1220676..1221449(+) (codY) [Staphylococcus aureus strain BPH2760 isolate BPH2760]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=994597 EW032_RS06175 WP_000055337.1 1220676..1221449(+) (codY) [Staphylococcus aureus strain BPH2760 isolate BPH2760]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGGTCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTTTTTCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428