Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   EW022_RS01995 Genome accession   NZ_LR130240
Coordinates   383957..384739 (+) Length   260 a.a.
NCBI ID   WP_021340905.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain PS006 isolate PS006     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 378957..389739
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW022_RS01975 - 379294..380259 (-) 966 WP_119774122.1 asparaginase -
  EW022_RS01980 - 380331..381719 (+) 1389 WP_010922607.1 Cof-type HAD-IIB family hydrolase -
  EW022_RS01985 - 381842..382294 (-) 453 WP_002992571.1 universal stress protein -
  EW022_RS01990 - 382525..383739 (+) 1215 WP_010922605.1 pyridoxal phosphate-dependent aminotransferase -
  EW022_RS01995 codY 383957..384739 (+) 783 WP_021340905.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  EW022_RS02000 - 384886..385440 (+) 555 WP_002988559.1 cysteine hydrolase family protein -
  EW022_RS02010 - 385978..386202 (+) 225 WP_014635660.1 putative PEP-binding protein -
  EW022_RS02015 gatC 386434..386736 (+) 303 WP_011285093.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  EW022_RS02020 gatA 386736..388202 (+) 1467 WP_003053823.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  EW022_RS02025 gatB 388202..389641 (+) 1440 WP_002983292.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28647.79 Da        Isoelectric Point: 4.5611

>NTDB_id=994500 EW022_RS01995 WP_021340905.1 383957..384739(+) (codY) [Streptococcus pyogenes strain PS006 isolate PS006]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASIIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=994500 EW022_RS01995 WP_021340905.1 383957..384739(+) (codY) [Streptococcus pyogenes strain PS006 isolate PS006]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACACTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAACTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAACGAAGGACGATTGACAGCTTCTATTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAATTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

65.759

98.846

0.65
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504