Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   AAYT23_RS08785 Genome accession   NZ_CP154877
Coordinates   1713991..1714815 (-) Length   274 a.a.
NCBI ID   WP_001036776.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 20234295     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1708991..1719815
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAYT23_RS08780 (AAYT23_08765) - 1712369..1713700 (-) 1332 WP_000390043.1 hemolysin family protein -
  AAYT23_RS08785 (AAYT23_08770) endA 1713991..1714815 (-) 825 WP_001036776.1 DNA-entry nuclease EndA Machinery gene
  AAYT23_RS08790 (AAYT23_08775) - 1714854..1715042 (-) 189 WP_001812859.1 DNA-directed RNA polymerase subunit beta -
  AAYT23_RS08795 (AAYT23_08780) murA 1715035..1716318 (-) 1284 WP_000358028.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  AAYT23_RS08800 (AAYT23_08785) - 1716342..1716572 (-) 231 WP_000250383.1 DUF1146 family protein -
  AAYT23_RS08805 (AAYT23_08790) sepM 1716630..1717667 (-) 1038 WP_000727277.1 SepM family pheromone-processing serine protease Regulator
  AAYT23_RS08810 (AAYT23_08795) coaD 1717651..1718139 (-) 489 WP_001280723.1 pantetheine-phosphate adenylyltransferase -
  AAYT23_RS08815 (AAYT23_08800) rsmD 1718129..1718668 (-) 540 WP_000706950.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  AAYT23_RS08820 (AAYT23_08805) asnA 1718733..1719725 (-) 993 WP_000747993.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29908.59 Da        Isoelectric Point: 10.1089

>NTDB_id=994474 AAYT23_RS08785 WP_001036776.1 1713991..1714815(-) (endA) [Streptococcus pneumoniae strain 20234295]
MNKKTRQTLIGLLVLLLLSAGSYYIKQNELGNQAAKTKMSQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=994474 AAYT23_RS08785 WP_001036776.1 1713991..1714815(-) (endA) [Streptococcus pneumoniae strain 20234295]
ATGAACAAAAAAACAAGACAGACACTGATTGGACTGCTAGTGTTATTGCTTTTGTCTGCAGGGAGCTATTATATTAAGCA
GAATGAACTAGGAAATCAGGCTGCTAAGACAAAAATGAGTCAGAAAAAACAAGCGTCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCTCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

95.985

100

0.96
  endA Streptococcus pneumoniae D39

95.985

100

0.96
  endA Streptococcus pneumoniae R6

95.985

100

0.96
  endA Streptococcus pneumoniae TIGR4

95.985

100

0.96

Multiple sequence alignment