Detailed information NTG0994444

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: AAYT23_RS04225
• Genome accession: NZ_CP154877
• Coordinates: 829435..831675 (+)
• Length: 746 a.a.
• NCBI ID: WP_000942413.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 20234295
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 824435..836675

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAYT23_RS04195 (AAYT23_04180)	-	824586..825554 (+)	969	WP_000658183.1	PhoH family protein	-
AAYT23_RS04200 (AAYT23_04185)	-	825747..826247 (+)	501	WP_000566988.1	GNAT family N-acetyltransferase	-
AAYT23_RS04205 (AAYT23_04190)	-	826250..826576 (+)	327	Protein_828	TfoX/Sxy family protein	-
AAYT23_RS04210 (AAYT23_04195)	ald	826877..827988 (-)	1112	Protein_829	alanine dehydrogenase	-
AAYT23_RS04215 (AAYT23_04200)	-	828165..828734 (+)	570	WP_000443743.1	GNAT family N-acetyltransferase	-
AAYT23_RS04220 (AAYT23_04205)	comEA/celA/cilE	828801..829451 (+)	651	WP_000387324.1	helix-hairpin-helix domain-containing protein	Machinery gene
AAYT23_RS04225 (AAYT23_04210)	comEC/celB	829435..831675 (+)	2241	WP_000942413.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
AAYT23_RS04230 (AAYT23_04215)	-	831854..832042 (+)	189	WP_001809102.1	hypothetical protein	-
AAYT23_RS04235 (AAYT23_04220)	-	832074..832661 (+)	588	WP_000933542.1	ATP-binding cassette domain-containing protein	-
AAYT23_RS04240 (AAYT23_04225)	-	832665..833846 (+)	1182	WP_000655952.1	membrane protein	-
AAYT23_RS04245 (AAYT23_04230)	infC	834153..834683 (+)	531	WP_000848180.1	translation initiation factor IF-3	-
AAYT23_RS04250 (AAYT23_04235)	rpmI	834716..834916 (+)	201	WP_001125943.1	50S ribosomal protein L35	-
AAYT23_RS04255 (AAYT23_04240)	rplT	834968..835327 (+)	360	WP_000124836.1	50S ribosomal protein L20	-
AAYT23_RS04260 (AAYT23_04245)	-	835385..835765 (+)	381	WP_000157138.1	VOC family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84642.24 Da
• Isoelectric Point: 9.6735

>NTDB_id=994444 AAYT23_RS04225 WP_000942413.1 829435..831675(+) (comEC/celB) [Streptococcus pneumoniae strain 20234295]
MLQWIKNFSIPLIYLSFLLLWLYYAIFSTSYLALLGFVFLLVCLFFQFPWKSASKVLVICGIFGFWFVFQNWQQSQASQN
LADSVERVRILPDTIKVNGDSLSFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIV
MPNFFFTAGGVLSCAYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFIFSFLFDLTFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASRPLVFGQPNTWLLILLLISLALVYDLRKNIKKLTVLCLLITGLFLLTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESYKKIKKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDK
EHVGDLSEMTKAFHVGEILVSKNSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRKMGDGGHDDTLVLYGKF
LDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSSSPAFLEKLKPELTLISVGKSNRMKLPYQETLTRLEGIN
SKVYRTDQQGAIRFKGLDSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=994444 AAYT23_RS04225 WP_000942413.1 829435..831675(+) (comEC/celB) [Streptococcus pneumoniae strain 20234295]
ATGTTACAGTGGATTAAGAATTTCTCTATTCCCCTAATTTACCTGAGTTTTCTGTTACTTTGGCTTTACTACGCCATTTT
TTCAACATCCTATCTTGCTTTGTTGGGATTTGTTTTTCTGCTAGTCTGTCTCTTTTTCCAATTTCCTTGGAAATCTGCTA
GCAAAGTTCTAGTGATTTGTGGAATCTTTGGATTTTGGTTTGTTTTTCAAAATTGGCAACAGAGTCAAGCGAGTCAAAAT
CTGGCGGATTCTGTTGAAAGGGTACGGATTTTGCCTGATACTATTAAGGTTAATGGTGATAGTCTATCCTTTCGTGGCAA
GTCTAACGGTCGTGCTTTCCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACCGACC
TGCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTAATTACCAAGCCTAT
CTGAAGACTCAGGGAATTTACCAGACTCTCAATATCAAAACAATCCAGTCACTTCAAAAGATTGGCAGTTGGGATATAGG
AGAAAACTTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGACGCACTTTCCAGACCCTATGCGCAATTACATGA
CAGGACTCTTGCTGGGACATCTGGACACCGACTTTGAGGAGATGAATGAGCTTTATTCCAGTCTAGGAATTATCCACCTC
TTTGCCCTATCTGGCATGCAGGTAGGTTTTTTCATGAATGGATTTAAGAAACTTCTCTTGCGATTGGGCTTGACCCAAGA
AAAGTTGAAATGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACGGTGCTTGTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTTACAGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTGCTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTATCTTTTCCTTTCTATTTGACTTGACCTTCTTACCGCTCTTGTCTATT
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTAGAGGGCATTATTCGCTTGGT
CTCGCAGGTGGCAAGTAGACCGCTTGTCTTTGGACAACCCAATACATGGCTTTTAATCCTATTGTTAATTTCTTTGGCTT
TGGTCTATGATTTGAGGAAAAACATTAAAAAGCTAACGGTATTGTGCTTATTGATTACAGGGCTCTTTCTCCTGACCAAG
CATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTAGGTGGTAAGGCAGAATCTTATAAGAAAATCAAAAAATGGCAAGAAAAGATGACGACCAGCAATG
CCCAGCGAAGCTTGATACCCTATCTCAAAAGTCGAGGAGTAGCTAAGATTGACCAGCTAATTTTGACTAACACGGACAAG
GAGCATGTTGGAGATTTGTCAGAGATGACCAAGGCTTTCCATGTAGGGGAGATTCTAGTATCAAAAAACAGTCTGAAACA
GAAGGAATTTGTGGCAGAACTACAGGCGACTCAAACAAAGGTGCGTAGTATGATAGTAGGGGAGAACTTGCCCATTTTTG
GAAGTCAGTTAGAAGTTCTATCTCCAAGGAAAATGGGAGATGGAGGACACGATGATACCCTAGTTCTGTATGGGAAATTC
TTGGATAAGCAATTTCTCTTCACGGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGCACTATCCAGACTTGAA
AGTAAATGTTTTGAAAGCTAGCCAACATGGCAATAAAAAATCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGC
TTACTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCTATCAGGAAACATTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTATCGAACTGACCAGCAAGGAGCTATACGTTTTAAGGGGTTGGATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (31-176)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-693)

• Competence protein (Competence) (216-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus pneumoniae Rx1	98.391	100	0.984
comEC/celB	Streptococcus pneumoniae D39	98.391	100	0.984
comEC/celB	Streptococcus pneumoniae R6	98.391	100	0.984
comEC/celB	Streptococcus pneumoniae TIGR4	97.587	100	0.976
comEC/celB	Streptococcus mitis SK321	91.287	100	0.913
comEC/celB	Streptococcus mitis NCTC 12261	90.872	99.866	0.908
comEC	Lactococcus lactis subsp. cremoris KW2	44.13	99.33	0.438