Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   EW023_RS07540 Genome accession   NZ_LR130239
Coordinates   1482740..1483522 (-) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes strain PS003 isolate PS003     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1477740..1488522
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW023_RS07510 gatB 1477837..1479276 (-) 1440 WP_011018162.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
  EW023_RS07515 gatA 1479276..1480742 (-) 1467 WP_023611911.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  EW023_RS07520 gatC 1480742..1481044 (-) 303 WP_002988561.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  EW023_RS07525 - 1481276..1481500 (-) 225 WP_002988560.1 putative PEP-binding protein -
  EW023_RS07535 - 1482039..1482593 (-) 555 WP_010922604.1 cysteine hydrolase family protein -
  EW023_RS07540 codY 1482740..1483522 (-) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  EW023_RS07545 - 1483740..1484954 (-) 1215 WP_010922605.1 pyridoxal phosphate-dependent aminotransferase -
  EW023_RS07550 - 1485185..1485637 (+) 453 WP_002992571.1 universal stress protein -
  EW023_RS07555 - 1485760..1487148 (-) 1389 WP_010922607.1 Cof-type HAD-IIB family hydrolase -
  EW023_RS07560 - 1487220..1488185 (+) 966 WP_002983258.1 asparaginase -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=994444 EW023_RS07540 WP_002983278.1 1482740..1483522(-) (codY) [Streptococcus pyogenes strain PS003 isolate PS003]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=994444 EW023_RS07540 WP_002983278.1 1482740..1483522(-) (codY) [Streptococcus pyogenes strain PS003 isolate PS003]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACACTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAACTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAACGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAACTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504

Multiple sequence alignment