Detailed information    

insolico Bioinformatically predicted

Overview

Name   recD/recD2/recDB   Type   Machinery gene
Locus tag   EW025_RS08725 Genome accession   NZ_LR130238
Coordinates   1654731..1657184 (+) Length   817 a.a.
NCBI ID   WP_010922636.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain HKU419 isolate HKU419     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1649731..1662184
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW025_RS08705 - 1652154..1652699 (-) 546 WP_011285701.1 CvpA family protein -
  EW025_RS08710 - 1652702..1653010 (-) 309 WP_002993251.1 hypothetical protein -
  EW025_RS08715 rnhC 1653167..1654069 (+) 903 WP_010922635.1 ribonuclease HIII -
  EW025_RS08720 lepB 1654080..1654673 (+) 594 WP_002983074.1 signal peptidase I -
  EW025_RS08725 recD/recD2/recDB 1654731..1657184 (+) 2454 WP_010922636.1 ATP-dependent RecD-like DNA helicase Machinery gene
  EW025_RS08730 - 1657275..1657757 (+) 483 WP_002983066.1 hypothetical protein -
  EW025_RS08735 dinB 1657850..1658944 (-) 1095 WP_011285702.1 DNA polymerase IV -
  EW025_RS08740 pflB 1659153..1661480 (+) 2328 WP_002988233.1 formate C-acetyltransferase -

Sequence

Protein


Download         Length: 817 a.a.        Molecular weight: 91429.34 Da        Isoelectric Point: 4.6190

>NTDB_id=994349 EW025_RS08725 WP_010922636.1 1654731..1657184(+) (recD/recD2/recDB) [Streptococcus pyogenes strain HKU419 isolate HKU419]
MEYVFTGTVDRIIFENQANFFKILLLAIEDTDSDIDDFEIIITGTMADIIEGDDYTFWGELTQHPKYGQQLKLSRYQKIK
PSSSGLVNYFSSDHFKGIGKKTAEKIIALYGHNTIDHILEDPSKLETISGLSKANRQAFVAKLKLNYGTEQLIAGLVELG
LSNRFALQAFEKYKEEALDLVKENPYQLVEDLQGFGFKMADALAENLGIESDSPKRFRAALLHCLLEESINRGDTYVQAR
QLLDFAITLLEDARQVECDPAAVAEQLSELIIEGKIKNSDTKLFDASLYFAEEGIANNISRLLDTPLSQSFSHDTIQTTI
QAVQKDFAITYDQVQQEAITKALTSKVFLLTGGPGTGKTTVIRGILQAYANLHQIDLDKKDLPILLAAPTGRAARRMNEL
TGLPSATIHRHLGLNGDNDYQAMEDYLDCDLLIVDEFSMVDTWLANQLLGAINSTTQVIIVGDSDQLPSVGPGQVLSDLL
KVNSLPQIALQKIFRQSQESTIVNLADQMRRGILAADFRDKKADRSYFEAQAAFIPDMIQKIVLSAIKSGIPAEEIQILA
PMYKGQAGINHLNQLMQELLNPLQGQTEFLFNDTHFRKGDKVLHLVNDAQLNVFNGDIGYITDLIPAKYTESKQDELILD
FDGSEVTYPRNEWLKLTLAYAMSIHKSQGSEFQVVILPITRQSGRLLQRNVIYTAITRSKSKLILLGEYTAFEYAIKHEG
DKRQTYLIERFQEQSDLASSQPNQELKSKEQTSLFSNTATLEDDSQKSSSQSTNSNPTENSQSDNDDFRLTPENYSTIDS
MIGLTESDIALFFQKKS

Nucleotide


Download         Length: 2454 bp        

>NTDB_id=994349 EW025_RS08725 WP_010922636.1 1654731..1657184(+) (recD/recD2/recDB) [Streptococcus pyogenes strain HKU419 isolate HKU419]
ATGGAATACGTTTTTACAGGTACTGTTGATCGTATCATTTTTGAAAACCAGGCTAATTTCTTTAAAATTCTCCTCCTTGC
CATTGAGGATACAGACAGTGACATTGACGACTTTGAAATCATTATCACAGGAACGATGGCTGACATTATTGAAGGAGATG
ACTACACCTTTTGGGGGGAATTGACCCAGCACCCTAAATATGGACAGCAACTCAAACTAAGCCGTTACCAAAAAATCAAA
CCTAGTTCATCTGGTTTGGTTAATTATTTCTCTAGCGACCATTTTAAGGGGATTGGTAAAAAAACAGCGGAGAAAATCAT
TGCGCTATATGGTCATAATACCATTGACCATATTTTAGAAGACCCAAGCAAATTAGAAACTATCTCTGGCCTATCTAAGG
CTAATCGTCAAGCCTTTGTCGCTAAACTAAAATTGAATTACGGCACAGAGCAACTGATTGCTGGTCTCGTCGAACTTGGC
CTTAGCAACCGTTTTGCCCTTCAAGCGTTTGAAAAGTATAAAGAAGAGGCTCTTGACCTTGTTAAAGAAAATCCCTATCA
GTTAGTCGAAGATCTACAAGGTTTTGGGTTTAAAATGGCAGATGCTCTCGCTGAAAACTTAGGGATTGAAAGCGACTCTC
CGAAACGTTTTCGTGCAGCCCTCCTTCACTGTCTCTTGGAAGAATCCATCAATCGAGGAGATACTTATGTCCAAGCACGA
CAATTATTAGACTTTGCCATCACACTCCTTGAAGATGCACGTCAAGTAGAATGTGATCCTGCTGCTGTGGCTGAACAACT
AAGCGAGTTAATCATAGAGGGCAAAATCAAAAACAGTGACACCAAACTGTTTGATGCTAGCCTTTATTTTGCTGAAGAAG
GGATTGCTAACAACATCTCTCGTCTCTTAGATACTCCTTTAAGTCAGTCATTTAGTCATGATACCATTCAAACAACCATC
CAAGCCGTTCAAAAAGACTTTGCCATCACCTATGACCAAGTGCAGCAAGAAGCCATTACTAAGGCTTTAACCAGCAAGGT
CTTTCTCCTAACAGGTGGTCCCGGAACAGGAAAAACAACTGTTATTCGAGGCATTTTGCAGGCTTACGCGAACCTGCATC
AGATTGATTTGGATAAAAAAGACCTTCCTATCTTGTTAGCAGCTCCAACAGGTCGGGCTGCACGTCGCATGAATGAGTTG
ACTGGACTTCCTAGCGCAACCATCCACAGGCACTTAGGCCTCAATGGCGACAACGATTACCAAGCCATGGAGGATTATCT
AGACTGCGACCTGCTGATTGTCGATGAATTTTCAATGGTGGATACCTGGCTTGCCAACCAGTTGTTAGGAGCTATTAACT
CAACAACTCAAGTGATTATTGTCGGAGATAGTGACCAGCTTCCTTCGGTTGGACCCGGTCAAGTCCTGTCAGATCTTTTA
AAAGTCAATAGCCTGCCCCAAATCGCCTTGCAAAAGATATTTCGTCAATCCCAAGAATCTACTATTGTCAATTTGGCAGA
CCAGATGCGTCGAGGAATCTTAGCTGCTGACTTTCGTGATAAAAAAGCTGACCGTTCTTATTTTGAAGCCCAAGCAGCCT
TTATCCCTGACATGATTCAAAAAATTGTCCTATCTGCTATTAAAAGTGGCATCCCTGCTGAGGAAATTCAAATTTTAGCA
CCTATGTACAAAGGACAAGCTGGCATCAATCATCTTAATCAACTCATGCAAGAACTTCTCAATCCCTTGCAAGGACAAAC
AGAATTTCTGTTCAATGATACGCATTTTCGTAAAGGTGATAAAGTCCTGCACTTAGTCAACGATGCTCAGTTGAATGTCT
TTAACGGAGATATTGGTTATATTACAGATTTGATTCCTGCTAAATACACCGAATCTAAGCAAGACGAATTAATCTTAGAT
TTTGACGGTAGCGAAGTCACGTACCCTAGAAATGAATGGCTAAAATTAACCCTGGCCTATGCCATGAGCATTCATAAATC
GCAAGGGAGTGAGTTTCAAGTGGTGATTTTACCTATCACACGCCAAAGCGGCCGACTCTTGCAACGAAATGTGATTTACA
CGGCCATTACTCGGTCTAAAAGTAAGTTAATTCTGTTGGGAGAATATACTGCCTTTGAGTATGCTATTAAACACGAAGGC
GATAAACGCCAAACCTACTTGATCGAACGCTTCCAAGAACAATCCGACTTAGCCTCCTCTCAACCTAACCAAGAGCTAAA
ATCAAAAGAGCAGACCTCCCTTTTTTCTAATACGGCAACCCTTGAGGACGACTCTCAAAAATCTTCCTCTCAATCAACAA
ACTCTAACCCCACTGAGAACTCTCAGTCAGATAATGATGATTTTAGGTTAACACCTGAGAATTATTCGACTATCGATTCG
ATGATAGGGCTTACAGAATCAGATATTGCCCTCTTTTTCCAGAAAAAATCCTAG

Domains

Predicted by InterProScan.

UvrD-like helicase C-terminal domain (UvrD_C_2)

(659-706)

Helix-hairpin-helix containing domain (HHH_RecD2)

(147-236)

AAA domain (AAA_30)

(331-522)

ATP-dependent RecD-like DNA helicase SH3 domain (SH3_13)

(572-641)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recD/recD2/recDB Bacillus subtilis subsp. subtilis str. 168

41.777

92.289

0.386

Multiple sequence alignment