Detailed information NTG0993726

Bioinformatically predicted

Overview

• Name: comFC/cflB
• Type: Machinery gene
• Locus tag: AAIS09_RS10410
• Genome accession: NZ_CP154595
• Coordinates: 2042450..2043112 (-)
• Length: 220 a.a.
• NCBI ID: WP_061813445.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain serotype 4
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2037450..2048112

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAIS09_RS10385 (AAIS09_10370)	-	2037601..2037867 (-)	267	WP_001278167.1	Veg family protein	-
AAIS09_RS10390 (AAIS09_10375)	dnaB	2037869..2039221 (-)	1353	WP_050137283.1	replicative DNA helicase	-
AAIS09_RS10395 (AAIS09_10380)	rplI	2039264..2039716 (-)	453	WP_000864220.1	50S ribosomal protein L9	-
AAIS09_RS10400 (AAIS09_10385)	-	2039713..2041686 (-)	1974	WP_000715123.1	DHH family phosphoesterase	-
AAIS09_RS10405 (AAIS09_10390)	hpf	2041822..2042370 (-)	549	WP_000599107.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
AAIS09_RS10410 (AAIS09_10395)	comFC/cflB	2042450..2043112 (-)	663	WP_061813445.1	ComF family protein	Machinery gene
AAIS09_RS10415 (AAIS09_10400)	comFA/cflA	2043109..2044407 (-)	1299	WP_000867609.1	DEAD/DEAH box helicase	Machinery gene
AAIS09_RS10420 (AAIS09_10405)	-	2044463..2045098 (+)	636	WP_000395739.1	YigZ family protein	-
AAIS09_RS10425 (AAIS09_10410)	cysK	2045383..2046303 (+)	921	WP_000029866.1	cysteine synthase A	-
AAIS09_RS10430 (AAIS09_10415)	-	2046542..2046892 (-)	351	Protein_2015	IS66 family transposase	-
AAIS09_RS10435 (AAIS09_10420)	-	2046892..2047184 (+)	293	Protein_2016	transposase	-
AAIS09_RS10440 (AAIS09_10425)	tnpB	2047325..2047540 (-)	216	WP_000376916.1	IS66 family insertion sequence element accessory protein TnpB	-

Sequence

Protein

• Length: 220 a.a.
• Molecular weight: 25275.11 Da
• Isoelectric Point: 7.3688

>NTDB_id=993726 AAIS09_RS10410 WP_061813445.1 2042450..2043112(-) (comFC/cflB) [Streptococcus pneumoniae strain serotype 4]
MKCLLCGQTMKTVLTFSSLLFLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide

• Length: 663 bp

>NTDB_id=993726 AAIS09_RS10410 WP_061813445.1 2042450..2043112(-) (comFC/cflB) [Streptococcus pneumoniae strain serotype 4]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTATTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAGGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

• Phosphoribosyl transferase domain (Pribosyltran) (153-219)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comFC/cflB	Streptococcus pneumoniae TIGR4	99.545	100	0.995
comFC/cflB	Streptococcus pneumoniae Rx1	99.091	100	0.991
comFC/cflB	Streptococcus pneumoniae D39	99.091	100	0.991
comFC/cflB	Streptococcus pneumoniae R6	99.091	100	0.991
comFC/cflB	Streptococcus mitis NCTC 12261	91.364	100	0.914
comFC/cflB	Streptococcus mitis SK321	90.909	100	0.909