Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   EQB41_RS08105 Genome accession   NZ_LR129840
Coordinates   1506634..1507422 (-) Length   262 a.a.
NCBI ID   WP_000940733.1    Uniprot ID   C1CSK2
Organism   Streptococcus pneumoniae strain 4496 isolate 4496     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1501634..1512422
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQB41_RS08080 - 1502621..1503133 (-) 513 WP_001049323.1 adenine phosphoribosyltransferase -
  EQB41_RS08085 - 1503220..1503978 (-) 759 WP_001287230.1 class I SAM-dependent methyltransferase -
  EQB41_RS11910 - 1504186..1504332 (+) 147 WP_001846606.1 hypothetical protein -
  EQB41_RS08090 - 1504479..1505609 (-) 1131 WP_127820823.1 ABC transporter ATP-binding protein -
  EQB41_RS08100 - 1506059..1506634 (-) 576 WP_000158725.1 cysteine hydrolase family protein -
  EQB41_RS08105 codY 1506634..1507422 (-) 789 WP_000940733.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  EQB41_RS08115 - 1507687..1509261 (-) 1575 WP_000671133.1 DEAD/DEAH box helicase -
  EQB41_RS08120 - 1509460..1510686 (-) 1227 WP_000841577.1 OFA family MFS transporter -
  EQB41_RS08125 - 1510880..1512196 (+) 1317 WP_000958947.1 FAD-containing oxidoreductase -

Sequence

Protein


Download         Length: 262 a.a.        Molecular weight: 29756.15 Da        Isoelectric Point: 5.7806

>NTDB_id=993674 EQB41_RS08105 WP_000940733.1 1506634..1507422(-) (codY) [Streptococcus pneumoniae strain 4496 isolate 4496]
MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNACIINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYV
QGANMIYETEANLPVEHDMSIFPVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLISDIFEEVKKRDY

Nucleotide


Download         Length: 789 bp        

>NTDB_id=993674 EQB41_RS08105 WP_000940733.1 1506634..1507422(-) (codY) [Streptococcus pneumoniae strain 4496 isolate 4496]
ATGGCACATTTATTAGAAAAAACTAGAAAAATTACATCAATTTTGAAACGCTCAGAGGAGCAGTTGCAGGATGAGCTTCC
TTACAACGCTATTACGCGTCAGTTAGCGGATATTATTCATTGCAATGCCTGCATTATCAATAGTAAGGGACGTCTGCTTG
GCTATTTTATGCGTTATAAAACAAATACAGATCGCGTAGAGCAATTCTTCCAAACTAAGATTTTCCCAGATGACTACGTT
CAAGGGGCTAATATGATTTACGAAACAGAAGCAAACTTACCTGTTGAGCATGATATGAGTATTTTCCCTGTTGAGAGTAG
AGATGATTTTCCAGATGGCTTGACGACTATTGCACCGATTCATGTATCGGGGATTCGCCTTGGTTCTTTGATTATTTGGC
GTAATGATAAAAAATTCGAAGATGAGGACTTGGTTCTTGTTGAGATTGCCAGTACCGTTGTTGGGATTCAGCTTCTTAAC
TTCCAACGTGAAGAAGATGAGAAAAATATTCGTCGTCGTACTGCTGTCACCATGGCGGTCAATACCCTTTCTTACTCCGA
ACTCCGTGCTGTTTCAGCAATTTTAGGGGAATTAAATGGAAATGAAGGGAAGTTGACTGCGTCAGTGATTGCAGATCGTA
TCGGAATCACTCGCTCTGTGATTGTCAATGCTCTTCGTAAACTTGAGTCTGCGGGGATTATTGAAAGTCGCTCACTTGGA
ATGAAGGGAACCTATCTTAAGGTCTTGATTTCAGATATTTTTGAAGAAGTGAAGAAAAGAGATTACTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-258)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C1CSK2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

62.595

100

0.626
  codY Bacillus subtilis subsp. subtilis str. 168

48.374

93.893

0.454

Multiple sequence alignment