Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | UXR08_RS00280 | Genome accession | NZ_CP154497 |
| Coordinates | 62269..63897 (-) | Length | 542 a.a. |
| NCBI ID | WP_001186602.1 | Uniprot ID | Q9XB94 |
| Organism | Staphylococcus aureus strain BSN57 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 57048..100773 | 62269..63897 | within | 0 |
| SCCmec | 43976..65268 | 62269..63897 | within | 0 |
Gene organization within MGE regions
Location: 43976..100773
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| UXR08_RS00185 (UXR08_00185) | mecA | 43976..45985 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| UXR08_RS00190 (UXR08_00190) | mecR1 | 46082..47839 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| UXR08_RS00195 (UXR08_00195) | mecI | 47839..48210 (+) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| UXR08_RS00200 (UXR08_00200) | psm-mec | 48295..48363 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| UXR08_RS00205 (UXR08_00205) | - | 48697..49827 (+) | 1131 | WP_010922808.1 | ROK family transcriptional regulator | - |
| UXR08_RS00210 (UXR08_00210) | cstB | 49941..51275 (-) | 1335 | Protein_39 | persulfide dioxygenase-sulfurtransferase CstB | - |
| UXR08_RS00215 (UXR08_00215) | - | 51308..52372 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| UXR08_RS00220 (UXR08_00220) | cstR | 52508..52768 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| UXR08_RS00225 (UXR08_00225) | - | 52768..53406 (+) | 639 | Protein_42 | sulfite exporter TauE/SafE family protein | - |
| UXR08_RS00230 (UXR08_00230) | - | 53751..54413 (-) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| UXR08_RS14955 | - | 54805..54864 (+) | 60 | WP_010959190.1 | erythromycin resistance leader peptide | - |
| UXR08_RS00235 (UXR08_00235) | erm(A) | 54874..55605 (+) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| UXR08_RS00240 (UXR08_00240) | - | 55731..56513 (-) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| UXR08_RS00245 (UXR08_00245) | - | 56664..57041 (-) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| UXR08_RS00250 (UXR08_00250) | - | 57048..58940 (-) | 1893 | WP_001557544.1 | site-specific integrase | - |
| UXR08_RS00255 (UXR08_00255) | - | 58937..60022 (-) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| UXR08_RS00260 (UXR08_00260) | - | 60141..60458 (-) | 318 | WP_000659050.1 | JAB domain-containing protein | - |
| UXR08_RS00265 (UXR08_00265) | - | 60479..60985 (-) | 507 | WP_001092169.1 | DUF1643 domain-containing protein | - |
| UXR08_RS00270 (UXR08_00270) | - | 61003..61314 (-) | 312 | WP_000700853.1 | DUF960 family protein | - |
| UXR08_RS00275 (UXR08_00275) | - | 61401..61751 (-) | 351 | WP_000859155.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| UXR08_RS00280 (UXR08_00280) | ccrB | 62269..63897 (-) | 1629 | WP_001186602.1 | cassette chromosome recombinase CcrB | Machinery gene |
| UXR08_RS00285 (UXR08_00285) | ccrA | 63919..65268 (-) | 1350 | WP_000815646.1 | cassette chromosome recombinase CcrA | Machinery gene |
| UXR08_RS00290 (UXR08_00290) | cch1 | 65502..67295 (-) | 1794 | WP_000195105.1 | cassette chromosome replicative helicase | - |
| UXR08_RS00295 (UXR08_00295) | ssb | 67295..67591 (-) | 297 | WP_000273824.1 | cassette chromosome ssDNA-binding protein | - |
| UXR08_RS00300 (UXR08_00300) | - | 67784..68830 (-) | 1047 | WP_001060127.1 | hypothetical protein | - |
| UXR08_RS00305 (UXR08_00305) | - | 69081..70222 (-) | 1142 | Protein_59 | IS3-like element ISSau4 family transposase | - |
| UXR08_RS00310 (UXR08_00310) | - | 70733..71668 (-) | 936 | Protein_60 | YfcC family protein | - |
| UXR08_RS00315 (UXR08_00315) | - | 72381..73076 (-) | 696 | WP_000858967.1 | response regulator transcription factor | - |
| UXR08_RS00320 (UXR08_00320) | - | 73051..75720 (-) | 2670 | WP_333482976.1 | sensor histidine kinase KdpD | - |
| UXR08_RS00325 (UXR08_00325) | kdpF | 75887..75967 (+) | 81 | WP_000631574.1 | K(+)-transporting ATPase subunit F | - |
| UXR08_RS00330 (UXR08_00330) | kdpA | 75988..77664 (+) | 1677 | WP_000029430.1 | potassium-transporting ATPase subunit KdpA | - |
| UXR08_RS00335 (UXR08_00335) | - | 77683..79704 (+) | 2022 | WP_333482977.1 | K(+)-transporting ATPase subunit B | - |
| UXR08_RS00340 (UXR08_00340) | - | 79720..80277 (+) | 558 | WP_001193482.1 | K(+)-transporting ATPase subunit C | - |
| UXR08_RS00345 (UXR08_00345) | - | 80822..81691 (-) | 870 | WP_000626133.1 | hypothetical protein | - |
| UXR08_RS00350 (UXR08_00350) | - | 81701..82597 (-) | 897 | WP_000411461.1 | DUF927 domain-containing protein | - |
| UXR08_RS00355 (UXR08_00355) | - | 83716..84342 (-) | 627 | WP_001176969.1 | hypothetical protein | - |
| UXR08_RS00360 (UXR08_00360) | - | 84457..85965 (+) | 1509 | WP_001001347.1 | protein kinase | - |
| UXR08_RS00365 (UXR08_00365) | - | 86215..86349 (-) | 135 | WP_001790628.1 | hypothetical protein | - |
| UXR08_RS00370 (UXR08_00370) | - | 86313..86405 (+) | 93 | WP_001790000.1 | hypothetical protein | - |
| UXR08_RS00375 (UXR08_00375) | - | 86552..88297 (+) | 1746 | WP_000700190.1 | DUF6119 family protein | - |
| UXR08_RS00380 (UXR08_00380) | - | 88395..88750 (-) | 356 | Protein_74 | tRNA-dihydrouridine synthase | - |
| UXR08_RS00385 (UXR08_00385) | - | 89055..89143 (-) | 89 | Protein_75 | hypothetical protein | - |
| UXR08_RS00390 (UXR08_00390) | - | 89241..89996 (-) | 756 | WP_000355845.1 | sulfite exporter TauE/SafE family protein | - |
| UXR08_RS00395 (UXR08_00395) | cstR | 89996..90256 (-) | 261 | WP_001105088.1 | persulfide-sensing transcriptional repressor CstR | - |
| UXR08_RS00400 (UXR08_00400) | cstA | 90393..91457 (+) | 1065 | WP_333482978.1 | persulfide response sulfurtransferase CstA | - |
| UXR08_RS00405 (UXR08_00405) | cstB | 91488..92822 (+) | 1335 | WP_000465472.1 | persulfide dioxygenase-sulfurtransferase CstB | - |
| UXR08_RS00410 (UXR08_00410) | sqr | 92841..94034 (+) | 1194 | WP_001033018.1 | type II sulfide:quinone oxidoreductase Sqr | - |
| UXR08_RS00415 (UXR08_00415) | - | 94301..94515 (-) | 215 | Protein_81 | universal stress protein | - |
| UXR08_RS00420 (UXR08_00420) | - | 94701..95687 (-) | 987 | WP_000662022.1 | tRNA-dihydrouridine synthase | - |
| UXR08_RS00425 (UXR08_00425) | - | 95996..96199 (+) | 204 | WP_000389759.1 | DUF6007 family protein | - |
| UXR08_RS00430 (UXR08_00430) | - | 96248..96544 (+) | 297 | WP_000201644.1 | TfoX/Sxy family protein | - |
| UXR08_RS00435 (UXR08_00435) | - | 96752..97354 (+) | 603 | WP_000908956.1 | hypothetical protein | - |
| UXR08_RS00440 (UXR08_00440) | - | 97621..100773 (+) | 3153 | WP_000080564.1 | ATP-binding protein | - |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62664.84 Da Isoelectric Point: 9.8600
>NTDB_id=993592 UXR08_RS00280 WP_001186602.1 62269..63897(-) (ccrB) [Staphylococcus aureus strain BSN57]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
Nucleotide
Download Length: 1629 bp
>NTDB_id=993592 UXR08_RS00280 WP_001186602.1 62269..63897(-) (ccrB) [Staphylococcus aureus strain BSN57]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
100 |
100 |
1 |