Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   E0E10_RS06960 Genome accession   NZ_LR027878
Coordinates   1337352..1338125 (+) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus strain BPH2003 isolate BPH2003     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1332352..1343125
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0E10_RS06940 trmFO 1332696..1334003 (+) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  E0E10_RS06945 xerC 1334420..1335316 (+) 897 WP_001015597.1 tyrosine recombinase XerC -
  E0E10_RS06950 hslV 1335313..1335858 (+) 546 WP_000072681.1 ATP-dependent protease subunit HslV -
  E0E10_RS06955 hslU 1335924..1337327 (+) 1404 WP_000379054.1 ATP-dependent protease ATPase subunit HslU -
  E0E10_RS06960 codY 1337352..1338125 (+) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  E0E10_RS06965 - 1338176..1338268 (+) 93 WP_001790530.1 hypothetical protein -
  E0E10_RS06970 rpsB 1338467..1339234 (+) 768 WP_000268484.1 30S ribosomal protein S2 -
  E0E10_RS06975 - 1339268..1339381 (+) 114 WP_001789890.1 hypothetical protein -
  E0E10_RS06980 tsf 1339416..1340297 (+) 882 WP_000201387.1 translation elongation factor Ts -
  E0E10_RS06985 pyrH 1340434..1341156 (+) 723 WP_000057330.1 UMP kinase -
  E0E10_RS06990 frr 1341175..1341729 (+) 555 WP_001280006.1 ribosome recycling factor -
  E0E10_RS06995 - 1342102..1342872 (+) 771 WP_000473701.1 isoprenyl transferase -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=993461 E0E10_RS06960 WP_000055337.1 1337352..1338125(+) (codY) [Staphylococcus aureus strain BPH2003 isolate BPH2003]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=993461 E0E10_RS06960 WP_000055337.1 1337352..1338125(+) (codY) [Staphylococcus aureus strain BPH2003 isolate BPH2003]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGGGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428

Multiple sequence alignment