Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   TTHNP4_RS11240 Genome accession   NZ_LR027517
Coordinates   1996643..1998877 (+) Length   744 a.a.
NCBI ID   WP_124105412.1    Uniprot ID   -
Organism   Thermus thermophilus isolate TTHNAR1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1991643..2003877
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TTHNP4_RS11225 (TTHN1_02263) - 1992194..1993522 (+) 1329 WP_124105410.1 ABC transporter permease subunit -
  TTHNP4_RS11230 (TTHN1_02264) - 1993523..1994842 (+) 1320 WP_124105411.1 sugar ABC transporter permease -
  TTHNP4_RS11235 (TTHN1_02265) - 1994839..1996551 (+) 1713 WP_172596955.1 glycoside hydrolase family 13 protein -
  TTHNP4_RS11240 (TTHN1_02266) mutS/mutS2 1996643..1998877 (+) 2235 WP_124105412.1 endonuclease MutS2 Machinery gene
  TTHNP4_RS11245 (TTHN1_02267) - 1998852..1999448 (-) 597 WP_252973303.1 TIGR00730 family Rossman fold protein -
  TTHNP4_RS11250 (TTHN1_02268) - 1999482..1999967 (+) 486 WP_252973304.1 IS630 family transposase -
  TTHNP4_RS11255 (TTHN1_02269) - 1999964..2000488 (+) 525 WP_014509880.1 IS630 family transposase -
  TTHNP4_RS11260 (TTHN1_02270) - 2000489..2000584 (-) 96 Protein_2210 TIGR00730 family Rossman fold protein -
  TTHNP4_RS11265 (TTHN1_02271) murI 2000614..2001387 (-) 774 WP_124105413.1 glutamate racemase -
  TTHNP4_RS11270 (TTHN1_02272) metK 2001481..2002659 (+) 1179 WP_165739197.1 methionine adenosyltransferase -
  TTHNP4_RS11275 (TTHN1_02273) - 2002708..2003796 (-) 1089 WP_124105415.1 GGDEF domain-containing protein -

Sequence

Protein


Download         Length: 744 a.a.        Molecular weight: 82365.33 Da        Isoelectric Point: 6.5588

>NTDB_id=992897 TTHNP4_RS11240 WP_124105412.1 1996643..1998877(+) (mutS/mutS2) [Thermus thermophilus isolate TTHNAR1]
MRDVLEVLEFPRVRALLAERAKTPLGRELALALAPLPREEAEKRHELTGEALSYPYALPEAGTLREAYGRALAGARLSGP
ELLKAAKALEEAMALKEELLPLKNALSQVAEGIGDHTPFLERVRKALDEEGAVKDEASPRLAQIRKELRPLRQQILDRLY
ALIDRHREAFQDRFVTLRRERYCVPVRAGMAQKVPGILLDESESGATLFIEPFSVVKLNNRLQALRLKEEEEVNRILRDL
SERLAKDEGVPKTLEALGLLDLVQAQAALARDLGLSRPALGERYELYRAFHPLIPNAVRNSFALDETNRILLISGPNMGG
KTALLKTLGLAVLMAQSGLFVAAEKALLAWPDRVFADIGDEQSLQENLSTFAGHLRRLKEMLEEATPNSLVLIDELGSGT
DPEEGAALSQAILEALLERGVKGMVTTHLSPLKAFAQGREGIQNASMRFDLEALRPTYELVLGVPGRSYALAIARRLALP
EEVLKRAEALLPEGGRLEALLERLEAERLALEAERERLRRELSQVERLREALAEREARFEEERAERLKALEEEVRAELLK
VEAELKALKEKARNEGKRDALRELMALRERYAKKAPPPPPPPGLAPGVLVEVPSLGKRGRVVELRGEEVLVQVGPLKMSL
KPQEVKPLPEAEPGKPLLAKPRREVKEVDLRGLTVAEALLEVDQALEEARALGLSTLRLLHGKGTGALRQAIREALRRDK
RVESFADAPPGEGGHGVTVVALRP

Nucleotide


Download         Length: 2235 bp        

>NTDB_id=992897 TTHNP4_RS11240 WP_124105412.1 1996643..1998877(+) (mutS/mutS2) [Thermus thermophilus isolate TTHNAR1]
GTGCGGGACGTCCTCGAGGTCCTGGAATTCCCCCGGGTCCGGGCCCTGCTGGCGGAGAGGGCCAAGACCCCCCTGGGCCG
GGAGCTTGCCCTGGCCCTCGCGCCCCTTCCCCGGGAAGAGGCGGAGAAGCGGCACGAGCTCACGGGGGAGGCCCTAAGCT
ACCCCTACGCCCTCCCCGAGGCGGGGACCTTAAGGGAGGCCTACGGGAGGGCCCTCGCGGGGGCGAGGCTTTCCGGCCCC
GAGCTCCTAAAGGCGGCCAAGGCCCTGGAGGAGGCCATGGCCCTGAAGGAGGAGCTCCTTCCCCTGAAAAACGCCTTAAG
CCAGGTGGCGGAGGGCATCGGGGACCACACCCCCTTCCTGGAGCGGGTGCGGAAGGCCCTGGACGAGGAGGGGGCGGTGA
AGGACGAGGCGAGCCCGAGGCTTGCCCAGATCCGAAAGGAGCTTAGGCCCCTCCGCCAGCAGATCCTGGACCGCCTCTAC
GCCCTCATAGACCGCCACAGGGAGGCCTTCCAGGACCGCTTCGTCACCCTAAGGCGGGAGCGCTACTGCGTCCCCGTGAG
GGCGGGGATGGCCCAGAAGGTGCCGGGGATCCTCCTGGACGAGTCCGAGTCGGGGGCGACCCTCTTCATAGAGCCCTTCT
CCGTGGTCAAGCTCAACAACCGCCTCCAGGCCCTGAGGCTAAAGGAGGAGGAGGAGGTGAACCGCATCCTCCGGGACCTC
TCCGAGAGGCTCGCCAAGGACGAGGGCGTGCCGAAGACCCTGGAGGCCCTGGGCCTTTTGGACCTCGTCCAGGCCCAGGC
CGCCTTGGCCCGGGACCTGGGGCTTTCCCGCCCTGCTCTTGGAGAGCGGTACGAGCTCTACCGGGCCTTTCACCCCCTGA
TCCCGAACGCCGTGCGGAACTCCTTCGCCCTGGACGAGACGAACCGCATCCTCCTCATCTCCGGGCCCAACATGGGGGGG
AAGACCGCCCTCCTTAAGACCCTGGGCCTTGCCGTCCTCATGGCCCAGTCCGGCCTCTTCGTGGCGGCGGAAAAGGCCCT
TTTGGCCTGGCCTGACCGGGTCTTTGCCGACATAGGGGACGAGCAGTCCTTGCAGGAAAACCTCTCCACCTTCGCCGGGC
ACTTAAGGCGCCTCAAGGAGATGCTGGAGGAGGCCACCCCGAATAGCCTCGTCCTCATTGACGAGCTCGGAAGCGGCACC
GACCCCGAGGAGGGGGCGGCCCTTTCCCAGGCCATCCTGGAGGCCCTCCTGGAGAGAGGGGTCAAGGGCATGGTCACCAC
CCATCTCTCCCCCCTAAAGGCCTTCGCCCAGGGAAGGGAGGGGATCCAGAACGCCTCCATGCGCTTTGACCTCGAGGCCT
TGCGCCCCACCTACGAGCTCGTTTTGGGGGTGCCGGGACGGAGCTACGCTCTGGCCATCGCGAGGAGGCTCGCCCTCCCC
GAGGAGGTCCTCAAGCGGGCCGAGGCCCTTTTGCCCGAGGGGGGGCGGCTGGAGGCCCTTCTGGAGAGGCTCGAGGCCGA
GCGCCTGGCCCTGGAGGCGGAGCGGGAACGCCTGAGGCGGGAGCTTTCCCAGGTGGAGAGGCTTAGGGAGGCCCTGGCCG
AGCGGGAGGCCCGTTTTGAAGAGGAGCGGGCGGAAAGGCTTAAGGCCCTCGAGGAGGAGGTGCGGGCCGAGCTCCTTAAG
GTGGAGGCCGAGCTCAAGGCCCTCAAGGAGAAGGCCAGGAACGAGGGCAAGCGGGACGCCCTCCGGGAACTCATGGCCCT
AAGGGAGCGCTACGCCAAAAAGGCCCCGCCGCCCCCGCCTCCGCCGGGCCTCGCCCCCGGGGTCTTGGTGGAGGTGCCGT
CCTTGGGCAAACGGGGCCGGGTGGTGGAGCTCAGGGGGGAGGAGGTCCTGGTCCAGGTGGGCCCCCTGAAGATGAGCCTC
AAGCCCCAGGAGGTGAAGCCCCTTCCCGAGGCCGAACCGGGCAAGCCCCTCCTCGCCAAGCCCCGACGGGAGGTAAAGGA
GGTGGACCTCCGGGGCCTCACGGTGGCCGAGGCCCTCCTGGAGGTGGACCAGGCCCTGGAGGAGGCGCGGGCCCTGGGCC
TTTCCACCCTCCGCCTCCTCCACGGCAAGGGGACGGGGGCCCTAAGGCAAGCCATCCGCGAGGCCCTTCGCCGGGACAAG
CGGGTGGAAAGCTTCGCCGATGCCCCGCCCGGCGAGGGGGGGCACGGGGTCACCGTGGTGGCGCTTCGGCCTTGA

Domains

Predicted by InterProScan.

MutS domain V (MutS_V)

(312-490)

MutS2 and Smr-associated SH3 domain (MSSS)

(606-644)

Smr domain (Smr)

(668-743)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

35.634

100

0.382