Detailed information NTG0991553

Bioinformatically predicted

Overview

• Name: mutS/mutS2
• Type: Machinery gene
• Locus tag: B6D67_RS08515
• Genome accession: NZ_LN831034
• Coordinates: 1597603..1599942 (-)
• Length: 779 a.a.
• NCBI ID: WP_010922633.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC8198
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1592603..1604942

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B6D67_RS08475 (ERS445054_01688)	rpsR	1592994..1593233 (-)	240	WP_002983142.1	30S ribosomal protein S18	-
B6D67_RS08480 (ERS445054_01689)	ssb	1593398..1593889 (-)	492	WP_002983122.1	single-stranded DNA-binding protein	Machinery gene
B6D67_RS08485 (ERS445054_01690)	rpsF	1593911..1594201 (-)	291	WP_002983117.1	30S ribosomal protein S6	-
B6D67_RS08490 (ERS445054_01691)	-	1594374..1594667 (-)	294	WP_002983113.1	hypothetical protein	-
B6D67_RS08495 (ERS445054_01692)	mutY	1594835..1595989 (+)	1155	WP_015055997.1	A/G-specific adenine glycosylase	-
B6D67_RS08500 (ERS445054_01693)	-	1596065..1596652 (+)	588	WP_010922631.1	helix-turn-helix domain-containing protein	-
B6D67_RS08505 (ERS445054_01694)	trxA	1596704..1597036 (-)	333	WP_001932060.1	thioredoxin	-
B6D67_RS08510 (ERS445054_01695)	-	1597099..1597599 (-)	501	WP_015055998.1	phosphatase PAP2 family protein	-
B6D67_RS08515 (ERS445054_01696)	mutS/mutS2	1597603..1599942 (-)	2340	WP_010922633.1	endonuclease MutS2	Machinery gene
B6D67_RS08520 (ERS445054_01697)	-	1600091..1600636 (-)	546	WP_010922634.1	CvpA family protein	-
B6D67_RS08525 (ERS445054_01698)	-	1600639..1600947 (-)	309	WP_002993251.1	hypothetical protein	-
B6D67_RS08530 (ERS445054_01699)	rnhC	1601104..1602006 (+)	903	WP_010922635.1	ribonuclease HIII	-
B6D67_RS08535 (ERS445054_01700)	lepB	1602017..1602610 (+)	594	WP_002983074.1	signal peptidase I	-

Sequence

Protein

• Length: 779 a.a.
• Molecular weight: 87803.99 Da
• Isoelectric Point: 6.4851

>NTDB_id=991553 B6D67_RS08515 WP_010922633.1 1597603..1599942(-) (mutS/mutS2) [Streptococcus pyogenes strain NCTC8198]
MNNKILEQLEFNKVKELLLPYLKTEQSQEELLELEPMTEAPKIEKSFNEISDMEQIFVEHHSFGIVSLSSISESLKRLEL
STDLNIQELLAIKKVLQSSSDMIHFYSDLDNVSFQSLDRLFENLEQFPNLQGSFQAINDGGFLEHFASPELERIRRQLTN
SERRVRQILQDMLKEKAELLSENLIASRSGRSVLPVKNTYRNRISGVVHDISSSGSTVYIEPRAVVTLNEEITQLRADER
HEEGRILHAFSDLLRPHVATIRNNAWILGHLDFVRAKYLFMSDNKATIPKISNDSTLALINVRHPLLSNPVANDLHFDHD
LTAIVITGPNTGGKTIMLKTLGLAQLMGQSGLPVLADKGSKIAVFNNIFADIGDEQSIEQSLSTFSSHMTHIVSILNEAD
HNSLVLFDELGAGTDPQEGASLAMAILEHLRLSHIKTMATTHYPELKAYGIETNFVENASMEFDAETLSPTYRFMQGVPG
RSNAFEIASRLGLAPFIVKQAKQMTDSDSDVNRIIEQLEAQTLETRRRLDHIKEVEQENLKFNRAVKKLYNEFSHERDKE
LEKIYQEAQEIVDMALNESDTILKKLNDKSQLKPHEIIDAKAQIKKLAPQVDLSKNKVLNKAKKIKAARAPRIGDDIIVT
SYGQRGTLTSQLKDGRWEAQVGIIKMTLTQDEFSLVRVQEEQKVKNKQINVVKKADGSGPRARLDLRGKRYEEAMQELDH
FIDQALLNNMGQVDIIHGIGTGVIREGVTKYLRRNKHVKHFAYAPQNAGGSGATIVTLG

Nucleotide

• Length: 2340 bp

>NTDB_id=991553 B6D67_RS08515 WP_010922633.1 1597603..1599942(-) (mutS/mutS2) [Streptococcus pyogenes strain NCTC8198]
ATGAATAACAAGATTTTAGAGCAGTTAGAATTTAACAAAGTTAAGGAATTGCTATTACCTTATCTCAAGACAGAACAATC
ACAAGAAGAATTATTAGAGCTGGAGCCGATGACGGAGGCTCCTAAAATAGAAAAAAGTTTTAATGAAATTTCTGACATGG
AACAGATTTTTGTTGAACATCACTCATTTGGCATAGTCAGCCTAAGTTCAATCTCTGAGAGTTTAAAACGCTTAGAGCTT
TCAACTGATCTTAATATTCAAGAACTTTTGGCTATCAAAAAAGTTTTACAGAGTTCTTCGGATATGATTCACTTTTATTC
TGATTTGGATAATGTTTCTTTCCAATCTTTGGATCGTTTGTTTGAAAATTTGGAACAATTCCCTAATCTGCAAGGGTCTT
TTCAAGCTATCAATGATGGTGGTTTTTTAGAACATTTTGCGAGTCCAGAATTAGAGCGTATCCGTCGTCAATTAACAAAT
AGTGAACGACGGGTTCGTCAGATTTTACAGGATATGCTTAAGGAAAAAGCAGAGCTTTTATCAGAGAATCTAATCGCTAG
TCGTAGTGGACGAAGTGTCCTACCAGTAAAAAATACTTATCGGAATCGTATTTCTGGTGTGGTTCATGACATCTCTTCTT
CAGGAAGTACTGTTTATATTGAGCCTCGTGCTGTAGTTACACTAAACGAAGAGATAACGCAGCTTAGAGCTGACGAACGC
CACGAAGAAGGTCGTATTTTACACGCATTTTCAGACTTGTTAAGACCTCATGTCGCCACTATTAGAAATAATGCATGGAT
TCTTGGGCATCTTGATTTTGTAAGGGCTAAATATCTTTTTATGTCTGATAATAAGGCGACGATACCTAAGATTTCTAATG
ACAGCACGTTAGCATTAATCAATGTTCGTCATCCTCTGTTAAGTAATCCTGTGGCTAATGACTTACATTTTGATCACGAT
TTAACTGCAATTGTCATCACTGGTCCCAATACTGGTGGTAAGACGATTATGCTAAAAACACTCGGTTTAGCACAATTAAT
GGGACAGTCTGGTTTGCCAGTATTAGCGGATAAAGGTAGTAAAATTGCAGTATTTAACAATATCTTTGCAGATATTGGCG
ATGAGCAATCTATTGAACAAAGTCTATCAACTTTTTCTAGTCATATGACGCACATAGTCAGTATTTTAAACGAGGCTGAC
CACAATAGTTTAGTTCTCTTTGATGAACTAGGAGCAGGAACGGATCCTCAAGAAGGTGCTAGTTTGGCCATGGCTATTTT
AGAACACCTTAGGTTAAGTCATATCAAAACGATGGCGACCACGCACTATCCAGAATTAAAAGCTTATGGGATTGAGACAA
ATTTTGTAGAGAATGCGAGCATGGAATTTGATGCAGAAACGCTTAGCCCCACATATCGCTTTATGCAAGGAGTTCCTGGA
CGCTCAAATGCATTTGAAATTGCTTCTCGCCTTGGTTTAGCTCCATTTATTGTTAAACAAGCTAAGCAGATGACAGATTC
TGACTCAGATGTTAACCGTATTATTGAACAGTTAGAGGCACAGACACTTGAGACACGTAGAAGACTGGATCATATTAAAG
AAGTTGAACAAGAAAACCTCAAATTCAATCGTGCGGTTAAGAAACTCTATAATGAATTTTCACATGAACGCGATAAAGAG
TTAGAAAAAATCTATCAAGAAGCTCAAGAAATTGTAGATATGGCTTTGAATGAGAGTGATACTATCTTAAAAAAACTCAA
TGATAAGAGCCAATTAAAACCTCACGAAATTATAGATGCTAAGGCACAAATAAAAAAATTAGCACCTCAAGTTGATTTAT
CAAAAAATAAAGTCTTAAATAAGGCTAAAAAAATCAAAGCAGCTCGTGCCCCTAGAATTGGTGATGATATTATAGTGACT
AGTTATGGACAGCGAGGTACCTTAACTAGTCAATTAAAAGATGGCCGTTGGGAAGCACAAGTGGGAATTATCAAAATGAC
ATTAACACAAGATGAATTTAGCCTCGTTAGAGTCCAAGAAGAACAGAAAGTCAAAAATAAACAGATTAATGTGGTTAAAA
AGGCTGATGGTTCTGGACCAAGGGCTCGACTTGATCTTAGAGGTAAAAGATACGAAGAAGCAATGCAAGAGTTAGATCAT
TTTATTGATCAAGCATTGCTTAACAATATGGGACAAGTTGATATCATTCATGGTATTGGTACAGGCGTTATTCGTGAGGG
AGTGACAAAATATCTTCGTCGTAATAAGCATGTTAAGCATTTTGCTTATGCCCCACAAAATGCAGGGGGATCTGGTGCCA
CAATTGTAACGTTAGGGTAA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (324-505)

• Smr domain (Smr) (704-778)

• MutS2 and Smr-associated SH3 domain (MSSS) (633-669)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
mutS/mutS2	Bacillus subtilis subsp. subtilis str. 168	40.506	100	0.411