Detailed information NTG0099084

Bioinformatically predicted

Overview

• Name: comYH
• Type: Machinery gene
• Locus tag: SP4011_RS01330
• Genome accession: NZ_AP026968
• Coordinates: 236924..237877 (+)
• Length: 317 a.a.
• NCBI ID: WP_000345093.1
• Uniprot ID: -
• Organism: Streptococcus parapneumoniae strain SP4011
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	228272..236321	236924..237877	flank	603

Gene organization within MGE regions

Location: 228272..237877

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SP4011_RS01290 (SP4011_02310)	-	228272..229114 (-)	843	WP_000840058.1	helix-turn-helix domain-containing protein	-
SP4011_RS01295 (SP4011_02320)	-	229311..229787 (-)	477	WP_000777684.1	GNAT family N-acetyltransferase	-
SP4011_RS01300 (SP4011_02330)	-	229900..231102 (-)	1203	WP_000855226.1	ATP-grasp domain-containing protein	-
SP4011_RS01305 (SP4011_02340)	-	231104..232003 (-)	900	WP_000771264.1	hypothetical protein	-
SP4011_RS01310 (SP4011_02350)	-	232004..233065 (-)	1062	WP_000604329.1	ATP-grasp domain-containing protein	-
SP4011_RS01315 (SP4011_02360)	-	233209..234192 (-)	984	WP_000864435.1	hypothetical protein	-
SP4011_RS01320 (SP4011_02370)	-	234167..235186 (-)	1020	WP_000612003.1	pyridoxal-phosphate dependent enzyme	-
SP4011_RS01325 (SP4011_02380)	-	235188..236402 (-)	1215	WP_000059523.1	MFS transporter	-
SP4011_RS11420	-	236521..236592 (-)	72	WP_148255730.1	SHP2/SHP3 family peptide pheromone	-
SP4011_RS01330 (SP4011_02390)	comYH	236924..237877 (+)	954	WP_000345093.1	class I SAM-dependent methyltransferase	Machinery gene

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 35611.87 Da
• Isoelectric Point: 4.2952

>NTDB_id=99084 SP4011_RS01330 WP_000345093.1 236924..237877(+) (comYH) [Streptococcus parapneumoniae strain SP4011]
MDFEKIEQAYTYLLENVQIIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDVIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLAKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVAARHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKGWLKEEASLVAMISLPENLFANAKQSKTIFILQKKSEIAVEPFIYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide

• Length: 954 bp

>NTDB_id=99084 SP4011_RS01330 WP_000345093.1 236924..237877(+) (comYH) [Streptococcus parapneumoniae strain SP4011]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAATTATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAATAGCATCTATTTGGATGGTGAGACTGAGCTAAACCAGGTCAAAGACAACAATC
AAGCCCTTAAACGCTTAGCGCTTCGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCAGATGTCATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGGTCTGGGATGGGAATTCTGGGCGCTACTTTCTTAACCTCTCTTGCTAAGA
AAGTGGATTACTTGGGAATGGAAGTGGATGATTTGCTGATTGATTTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGTTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGTGATGTGGTCATCAGCGACTTGCCTGTCGG
CTATTATCCTGATGATGCCGTTGCAGCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTTA
TGGAACAAGGACTTAAGTACCTCAAGTCAGATGGATATGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGCCCTCAA
AGTGATTTGTTGAAAGGGTGGTTGAAAGAAGAAGCAAGTCTGGTTGCTATGATTAGTTTGCCTGAAAATCTCTTTGCTAA
TGCCAAACAATCTAAGACTATTTTTATCCTACAGAAGAAAAGTGAAATAGCAGTGGAGCCTTTTATTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

• N-6 DNA Methylase (N6_Mtase) (69-282)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYH	Streptococcus mutans UA140	54.633	98.738	0.539
comYH	Streptococcus mutans UA159	54.313	98.738	0.536