Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   HMPREF9425_RS01175 Genome accession   NZ_GL831112
Coordinates   219270..221618 (-) Length   782 a.a.
NCBI ID   WP_003093819.1    Uniprot ID   -
Organism   Streptococcus vestibularis ATCC 49124     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 214270..226618
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF9425_RS01160 (HMPREF9425_0237) - 215032..215964 (+) 933 WP_003094167.1 metal ABC transporter substrate-binding protein -
  HMPREF9425_RS01165 tpx 216052..216543 (+) 492 Protein_230 thiol peroxidase -
  HMPREF9425_RS01170 (HMPREF9425_0240) - 218975..219202 (-) 228 WP_003093611.1 hypothetical protein -
  HMPREF9425_RS01175 (HMPREF9425_0241) mutS/mutS2 219270..221618 (-) 2349 WP_003093819.1 endonuclease MutS2 Machinery gene
  HMPREF9425_RS01180 (HMPREF9425_0242) polA 221793..224432 (+) 2640 WP_003094257.1 DNA polymerase I -
  HMPREF9425_RS01185 (HMPREF9425_0243) mutY 224738..225889 (-) 1152 WP_003096042.1 A/G-specific adenine glycosylase -

Sequence

Protein


Download         Length: 782 a.a.        Molecular weight: 87706.98 Da        Isoelectric Point: 6.5913

>NTDB_id=989480 HMPREF9425_RS01175 WP_003093819.1 219270..221618(-) (mutS/mutS2) [Streptococcus vestibularis ATCC 49124]
MNTKILDQLEFNKVKDQFTEYLQTEQAQAELRDLVPMTNPERIQNQFTEIQEMSEIFVEHHSFAIGSLRDISESLRRLEL
DADLNIQELISIKKVLQASADLGRFYADLENVELVALKRLFEKIEAFPSLQGSLQSINDGGFIEHFASPELQNIRRQLKS
CDDAIRQTLQDILKKSGHMLAESLIASRNGRSVLPVKNTYRNRIAGVVHDISSSGNTVYIEPRAVIQLNEEITQLRADER
HEMTRILHELSNQLRPQAAAIANNAWILGHMDFIRGKYLYLQDKKAVIPKISDNQTLQLLNVRHPLLVNPVANDLHFDED
LTAIVITGPNTGGKTVMLKTLGLAQLMAQSGLPILADKGSRVAIFQEIFADIGDEQSIEQSLSTFSSHMTHIVEILDAAD
SNSLVLVDELGAGTDPQEGASLAMAILEHLRLSQIKTMATTHYPELKAYGIETQHVENASMEFDTATLSPTYRFMQGVPG
RSNAFEIARRLGLNEIIVKEAENLTDTDSDVNRIIEQLEAQTVETQKRLEHIKDVEQENLKFNRAVKKLYNEFSHEYDKE
LEKAQKDIQDMVDTALAESDSILKTLHDKSQLKPHEVIDAKGKLKKLAPQVDLSKNKVLRKAKKEKTTRAPRVGDDIIVT
AYGQRGTLTSQAKNGNWEAQVGLIKMTLKADEFTLVRAQAEVKQPKKKQINVVKKAKKASGGPRARLDLRGKRYEEAMQE
LDAFIDQALLNNMSQVDIIHGIGTGVIRDAVTKYLRRHRHVKSFEYAPQSAGGSGCTIATLG

Nucleotide


Download         Length: 2349 bp        

>NTDB_id=989480 HMPREF9425_RS01175 WP_003093819.1 219270..221618(-) (mutS/mutS2) [Streptococcus vestibularis ATCC 49124]
ATGAACACAAAGATTTTAGATCAATTAGAATTTAACAAGGTCAAGGACCAGTTCACAGAATACCTACAGACTGAGCAGGC
TCAGGCGGAGTTACGTGACTTGGTGCCTATGACCAATCCAGAAAGAATTCAAAATCAATTTACAGAAATCCAAGAAATGT
CTGAGATTTTCGTAGAGCATCATAGCTTTGCCATTGGGAGCTTAAGAGATATTTCTGAGTCCTTGCGTCGCTTGGAACTG
GATGCTGACCTCAACATCCAGGAGCTCATTTCCATCAAGAAGGTCTTGCAAGCTTCAGCTGACCTTGGTCGATTCTACGC
TGACCTTGAAAATGTTGAGCTCGTCGCTCTAAAACGTCTTTTCGAAAAGATTGAAGCCTTTCCAAGTCTACAAGGCAGTC
TTCAGAGCATCAATGACGGTGGTTTTATTGAGCATTTTGCTAGCCCAGAGTTGCAAAATATCCGTCGTCAACTTAAATCT
TGCGATGATGCCATTCGCCAGACCTTACAAGACATTCTCAAGAAATCTGGCCACATGTTGGCTGAGAGTTTGATTGCTAG
TCGTAATGGTCGTTCAGTGCTTCCTGTCAAAAATACCTACCGTAACCGTATTGCTGGGGTGGTGCATGACATCTCAAGCT
CTGGAAATACCGTTTATATCGAGCCACGCGCCGTTATCCAGCTTAACGAAGAAATTACACAATTACGTGCAGACGAACGC
CACGAGATGACCCGTATCCTGCATGAACTGTCTAATCAACTACGCCCACAAGCTGCTGCAATTGCTAACAACGCTTGGAT
TTTGGGCCACATGGACTTCATTCGAGGAAAATACCTCTATCTCCAAGATAAGAAGGCGGTTATTCCAAAGATTAGTGACA
ACCAAACACTCCAACTGCTTAACGTTCGTCACCCGCTCTTGGTCAATCCAGTAGCCAACGATTTACACTTTGATGAGGAC
CTCACAGCCATTGTCATTACAGGTCCCAATACCGGTGGTAAAACGGTCATGCTTAAAACTCTAGGACTAGCTCAACTGAT
GGCTCAATCTGGCCTTCCAATTTTGGCTGATAAGGGTAGTCGTGTAGCCATTTTCCAAGAGATTTTTGCGGACATCGGAG
ATGAACAGTCTATCGAACAGAGCTTGTCTACTTTCTCTAGTCACATGACGCACATTGTCGAGATTCTGGACGCTGCCGAC
AGCAACAGTCTTGTCTTGGTCGATGAGCTTGGGGCTGGTACTGACCCTCAGGAGGGGGCTAGTCTAGCCATGGCAATCCT
AGAGCACCTTCGTTTGAGCCAGATTAAGACCATGGCTACCACTCACTATCCTGAGCTTAAGGCCTATGGAATTGAGACGC
AACATGTGGAAAATGCCAGCATGGAGTTTGACACAGCGACTTTAAGCCCTACCTATCGTTTTATGCAGGGGGTTCCTGGT
CGTTCTAATGCCTTTGAGATTGCTCGCCGCCTCGGATTGAATGAAATTATTGTCAAGGAAGCAGAGAACCTCACGGATAC
TGATAGTGATGTCAACCGTATCATCGAGCAACTTGAAGCCCAAACCGTCGAAACGCAAAAACGTCTGGAACACATCAAGG
ACGTTGAGCAAGAGAACCTTAAATTCAACCGTGCGGTCAAGAAACTCTATAACGAATTCTCCCATGAGTACGACAAGGAA
CTCGAAAAGGCTCAAAAAGACATTCAAGATATGGTGGATACAGCTTTGGCTGAGAGCGATAGTATTCTCAAAACTCTCCA
TGATAAGAGTCAACTCAAGCCTCATGAAGTTATCGACGCCAAAGGAAAACTCAAGAAACTTGCCCCACAAGTGGACCTCT
CTAAGAATAAGGTCCTTCGTAAAGCCAAGAAAGAAAAGACTACGCGTGCCCCTCGTGTCGGAGACGATATCATCGTTACC
GCCTACGGTCAACGGGGTACTCTTACCAGTCAGGCCAAAAATGGTAACTGGGAAGCTCAGGTCGGTCTCATCAAGATGAC
TCTCAAGGCAGACGAATTCACTCTGGTTCGTGCTCAAGCTGAGGTGAAACAGCCTAAGAAAAAACAGATTAACGTAGTTA
AAAAAGCCAAGAAGGCATCTGGTGGTCCTCGTGCCCGTCTAGACCTTCGTGGGAAACGTTACGAAGAAGCCATGCAAGAG
CTTGATGCCTTTATTGACCAAGCCCTACTTAACAACATGAGTCAGGTGGACATCATCCACGGTATTGGTACCGGTGTCAT
CCGTGACGCAGTGACTAAATATCTCCGCCGTCATCGTCATGTTAAAAGTTTTGAATATGCTCCACAAAGTGCCGGTGGTT
CCGGATGCACCATTGCAACCTTGGGATAA

Domains

Predicted by InterProScan.

MutS domain V (MutS_V)

(324-505)

MutS2 and Smr-associated SH3 domain (MSSS)

(633-672)

Smr domain (Smr)

(707-781)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

39.47

100

0.4

Multiple sequence alignment