Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   AAHH81_RS08875 Genome accession   NZ_CP152418
Coordinates   1745152..1745976 (-) Length   274 a.a.
NCBI ID   WP_050204516.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 20234287     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1740152..1750976
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAHH81_RS08870 (AAHH81_08855) - 1743592..1744923 (-) 1332 WP_000390049.1 hemolysin family protein -
  AAHH81_RS08875 (AAHH81_08860) endA 1745152..1745976 (-) 825 WP_050204516.1 DNA-entry nuclease EndA Machinery gene
  AAHH81_RS08880 (AAHH81_08865) - 1746015..1746203 (-) 189 WP_001818955.1 DNA-directed RNA polymerase subunit beta -
  AAHH81_RS08885 (AAHH81_08870) murA 1746196..1747479 (-) 1284 WP_000358028.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  AAHH81_RS08890 (AAHH81_08875) - 1747503..1747733 (-) 231 WP_000250393.1 DUF1146 family protein -
  AAHH81_RS08895 (AAHH81_08880) sepM 1747791..1748828 (-) 1038 WP_000727277.1 SepM family pheromone-processing serine protease Regulator
  AAHH81_RS08900 (AAHH81_08885) coaD 1748812..1749300 (-) 489 WP_001280740.1 pantetheine-phosphate adenylyltransferase -
  AAHH81_RS08905 (AAHH81_08890) rsmD 1749290..1749829 (-) 540 WP_369916964.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  AAHH81_RS08910 (AAHH81_08895) asnA 1749894..1750886 (-) 993 WP_000747995.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29969.67 Da        Isoelectric Point: 10.1700

>NTDB_id=989095 AAHH81_RS08875 WP_050204516.1 1745152..1745976(-) (endA) [Streptococcus pneumoniae strain 20234287]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLSQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKTTRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=989095 AAHH81_RS08875 WP_050204516.1 1745152..1745976(-) (endA) [Streptococcus pneumoniae strain 20234287]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGACAGCTAATAGTCCTAAAACCAAGCTTAGTCAGAAAAAACAAGCGTCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGACCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCTAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

98.175

100

0.982
  endA Streptococcus pneumoniae D39

98.175

100

0.982
  endA Streptococcus pneumoniae R6

98.175

100

0.982
  endA Streptococcus pneumoniae TIGR4

98.175

100

0.982

Multiple sequence alignment