Detailed information NTG0098758

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: R8624_RS08495
• Genome accession: NZ_AP026930
• Coordinates: 1670136..1671203 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159554.1
• Uniprot ID: A0A062WMA1
• Organism: Streptococcus pneumoniae strain PZ900701208
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1665136..1676203

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8624_RS08470 (PC1195_16750)	treR	1665323..1666033 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
R8624_RS08475 (PC1195_16760)	-	1666066..1666869 (-)	804	WP_000157656.1	ABC transporter ATP-binding protein	-
R8624_RS08480	-	1666882..1667759 (-)	878	Protein_1679	ABC transporter permease	-
R8624_RS08485	-	1667771..1668580 (-)	810	Protein_1680	ABC transporter substrate-binding protein	-
R8624_RS08490 (PC1195_16810)	amiF	1669199..1670125 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
R8624_RS08495 (PC1195_16820)	amiE	1670136..1671203 (-)	1068	WP_000159554.1	ABC transporter ATP-binding protein	Regulator
R8624_RS08500 (PC1195_16830)	amiD	1671212..1672138 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
R8624_RS08505 (PC1195_16840)	amiC	1672138..1673634 (-)	1497	WP_000759907.1	ABC transporter permease	Regulator
R8624_RS08510 (PC1195_16850)	amiA3	1673701..1675680 (-)	1980	WP_000742233.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39490.09 Da
• Isoelectric Point: 4.8727

>NTDB_id=98758 R8624_RS08495 WP_000159554.1 1670136..1671203(-) (amiE) [Streptococcus pneumoniae strain PZ900701208]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=98758 R8624_RS08495 WP_000159554.1 1670136..1671203(-) (amiE) [Streptococcus pneumoniae strain PZ900701208]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A062WMA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541