Detailed information NTG0986516

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: ACOCJF_RS10245
• Genome accession: NZ_CP184555
• Coordinates: 2058541..2059314 (-)
• Length: 257 a.a.
• NCBI ID: WP_000055337.1
• Uniprot ID: P63843
• Organism: Staphylococcus aureus strain SCTW2018694
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 2053541..2064314

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACOCJF_RS10210 (ACOCJF_10210)	-	2053794..2054564 (-)	771	WP_000473705.1	isoprenyl transferase	-
ACOCJF_RS10215 (ACOCJF_10215)	frr	2054937..2055491 (-)	555	WP_001280006.1	ribosome recycling factor	-
ACOCJF_RS10220 (ACOCJF_10220)	pyrH	2055510..2056232 (-)	723	WP_000057330.1	UMP kinase	-
ACOCJF_RS10225 (ACOCJF_10225)	tsf	2056369..2057250 (-)	882	WP_000201387.1	translation elongation factor Ts	-
ACOCJF_RS10230 (ACOCJF_10230)	-	2057285..2057398 (-)	114	WP_001789890.1	hypothetical protein	-
ACOCJF_RS10235 (ACOCJF_10235)	rpsB	2057432..2058199 (-)	768	WP_000268484.1	30S ribosomal protein S2	-
ACOCJF_RS10240 (ACOCJF_10240)	-	2058398..2058490 (-)	93	WP_001790530.1	hypothetical protein	-
ACOCJF_RS10245 (ACOCJF_10245)	codY	2058541..2059314 (-)	774	WP_000055337.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
ACOCJF_RS10250 (ACOCJF_10250)	hslU	2059339..2060742 (-)	1404	WP_000379054.1	ATP-dependent protease ATPase subunit HslU	-
ACOCJF_RS10255 (ACOCJF_10255)	hslV	2060808..2061353 (-)	546	WP_000072681.1	ATP-dependent protease subunit HslV	-
ACOCJF_RS10260 (ACOCJF_10260)	xerC	2061350..2062246 (-)	897	WP_001015606.1	tyrosine recombinase XerC	-
ACOCJF_RS10265 (ACOCJF_10265)	trmFO	2062663..2063970 (-)	1308	WP_000195254.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28755.13 Da
• Isoelectric Point: 6.0680

>NTDB_id=986516 ACOCJF_RS10245 WP_000055337.1 2058541..2059314(-) (codY) [Staphylococcus aureus strain SCTW2018694]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide

• Length: 774 bp

>NTDB_id=986516 ACOCJF_RS10245 WP_000055337.1 2058541..2059314(-) (codY) [Staphylococcus aureus strain SCTW2018694]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTTTTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTTATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAGTAG

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (2-178)

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

3D structure

• AlphaFold DB: P63843

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	64.202	100	0.642
codY	Lactococcus lactis subsp. lactis strain DGCC12653	42.802	100	0.428