Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   R8623_RS08065 Genome accession   NZ_AP026928
Coordinates   1583432..1585411 (-) Length   659 a.a.
NCBI ID   WP_000614540.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700406     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1578432..1590411
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8623_RS08035 (PC0401_15790) - 1578530..1579804 (-) 1275 WP_000704379.1 hydroxymethylglutaryl-CoA reductase, degradative -
  R8623_RS08040 (PC0401_15800) - 1579804..1580976 (-) 1173 WP_000151960.1 hydroxymethylglutaryl-CoA synthase -
  R8623_RS08045 (PC0401_15810) - 1581107..1581355 (-) 249 WP_001818278.1 hypothetical protein -
  R8623_RS08050 (PC0401_15820) - 1581423..1582046 (-) 624 Protein_1593 transposase family protein -
  R8623_RS08055 (PC0401_15830) - 1582108..1582557 (-) 450 WP_000176924.1 threonine/serine exporter family protein -
  R8623_RS08060 (PC0401_15840) - 1582559..1583317 (-) 759 WP_000392877.1 threonine/serine exporter ThrE family protein -
  R8623_RS08065 (PC0401_15850) stkP 1583432..1585411 (-) 1980 WP_000614540.1 serine/threonine-protein kinase StkP Regulator
  R8623_RS08070 (PC0401_15860) - 1585408..1586148 (-) 741 WP_000406248.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  R8623_RS08075 (PC0401_15870) rsmB 1586163..1587476 (-) 1314 WP_001820765.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  R8623_RS08080 (PC0401_15880) fmt 1587469..1588404 (-) 936 WP_000163683.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 659 a.a.        Molecular weight: 72316.86 Da        Isoelectric Point: 9.0945

>NTDB_id=98596 R8623_RS08065 WP_000614540.1 1583432..1585411(-) (stkP) [Streptococcus pneumoniae strain PZ900700406]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYNRRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIK
NPSQAVTEETYQPQAPKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANFEIGEEKTE
ASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSDVIAELKEKKVPDNLIKIEEEESNESEAGTV
LKQSLPEGTTYDLSKATQIVLTVAKKATTIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAG
TTYDVSKPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVEGMVVEQSPRAGEKVDL
NKTRVKISIYKPKTTSATP

Nucleotide


Download         Length: 1980 bp        

>NTDB_id=98596 R8623_RS08065 WP_000614540.1 1583432..1585411(-) (stkP) [Streptococcus pneumoniae strain PZ900700406]
ATGATCCAAATCGGCAAGATTTTTGCCGGACGCTATCGGATTGTCAAACAGATTGGTCGAGGAGGCATGGCGGATGTTTA
CCTAGCCAAAGACTTAATCTTAGATGGGGAAGAAGTGGCAGTGAAGGTTCTGAGGACCAACTACCAGACGGACCCGATAG
CTGTAGCTCGTTTTCAGCGTGAAGCGAGAGCTATGGCAGATCTAGACCATCCTCATATCGTTCGGATAACAGATATTGGT
GAGGAAGACGGTCAACAGTATCTTGCAATGGAGTATGTTGCTGGACTAGACCTCAAACGCTATATCAAGGAACATTATCC
TCTTTCTAATGAAGAAGCCGTCCGTATCATGGGACAAATTCTCTTGGCTATGCGCTTGGCCCATACTCGAGGAATTGTTC
ACAGGGACTTGAAACCTCAAAATATCCTTTTGACACCAGATGGGACTGCCAAGGTCACAGACTTTGGGATTGCTGTAGCC
TTTGCAGAGACAAGTCTGACCCAGACTAACTCGATGTTGGGCTCAGTTCATTACTTGTCACCAGAGCAGGCGCGTGGTTC
TAAGGCGACTGTGCAGAGTGATATCTATGCCATGGGGATTATTTTCTATGAGATGTTGACAGGCCATATCCCTTATGACG
GGGATAGCGCGGTGACCATTGCCCTCCAGCATTTCCAGAAACCCCTGCCGTCCGTTATTGCAGAAAATCCATCTGTACCT
CAGGCTTTAGAAAATGTTATTATCAAGGCAACTGCTAAAAAGTTGACCAATCGCTACCGATCGGTTTCAGAGATGTATGT
GGACTTGTCTAGTAGCTTGTCCTACAATCGTAGAAATGAAAGTAAGTTAATCTTTGATGAAACGAGCAAGGCAGATACCA
AGACCTTGCCGAAGGTTTCTCAGAGTACCTTGACATCTATTCCTAAGGTTCAAGCGCAGACAGAACACAAATCAATCAAA
AACCCAAGCCAGGCTGTGACAGAGGAAACTTACCAACCACAAGCACCGAAAAAACATAGATTTAAGATGCGTTACCTGAT
TTTGTTGGCCAGCCTTGTATTGGTGGCAGCTTCTCTTATTTGGATCTTATCCAGAACTCCTGCAACCATTGCCATTCCGG
ATGTGGCAGGTCAGACAGTTGCAGAGGCCAAGGCAACGCTCAAAAAAGCCAATTTTGAGATTGGTGAGGAGAAGACAGAG
GCTAGTGAAAAGGTGGAAGAAGGGCGGATTATCCGTACAGATCCTGGCGCTGGAACTGGTCGAAAAGAAGGAACGAAAAT
CAATCTGGTTGTCTCATCAGGCAAACAATCCTTCCAAATTAGTAATTATGTCGGCCGGAAATCTTCTGATGTTATCGCGG
AATTAAAAGAGAAAAAAGTTCCAGATAATTTGATTAAAATTGAGGAAGAAGAGTCCAATGAGAGTGAGGCTGGAACGGTC
CTGAAGCAAAGTCTACCAGAAGGTACGACCTATGACTTGAGCAAGGCAACTCAAATTGTTTTGACAGTAGCTAAAAAAGC
TACGACGATTCAATTAGGGAACTATATTGGACGGAACTCTACAGAAGTAATCTCAGAACTCAAGCAGAAGAAGGTTCCTG
AGAATTTGATTAAGATAGAGGAAGAAGAGTCCAGCGAAAGCGAACCAGGAACGATTATGAAACAAAGTCCAGGTGCCGGA
ACGACTTATGATGTGAGTAAACCTACTCAAATTGTCTTGACAGTAGCTAAAAAAGTTACAAGTGTTGCCATGCCGAGTTA
CATTGGTTCCAGCTTGGAGTTTACTAAGAACAATTTGATTCAAATTGTTGGGATTAAGGAAGCTAATATAGAAGTTGTAG
AAGTGACGACAGCGCCTGCAGGTAGTGTAGAAGGCATGGTTGTTGAACAAAGTCCTAGAGCAGGTGAAAAGGTAGACCTA
AATAAGACTAGAGTCAAGATTTCAATCTACAAACCTAAAACAACTTCAGCTACTCCTTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(440-505)

PASTA domain (PASTA)

(582-651)

PASTA domain (PASTA)

(513-577)

PASTA domain (PASTA)

(371-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

99.848

100

0.998
  stkP Streptococcus pneumoniae D39

99.697

100

0.997
  stkP Streptococcus pneumoniae R6

99.697

100

0.997
  stkP Streptococcus pneumoniae Rx1

99.545

100

0.995
  pknB Streptococcus mutans UA159

52.65

88.771

0.467
  stkP/pknB Streptococcus salivarius strain HSISS4

51.807

88.164

0.457

Multiple sequence alignment