Detailed information NTG0098581

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: R8623_RS04565
• Genome accession: NZ_AP026928
• Coordinates: 893989..894942 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495911.1
• Uniprot ID: Q8DQ27
• Organism: Streptococcus pneumoniae strain PZ900700406
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 888989..899942

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8623_RS04540	rpmG	889732..889881 (+)	150	WP_001809104.1	50S ribosomal protein L33	-
R8623_RS04545 (PC0401_08860)	secG	889921..890154 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
R8623_RS04550 (PC0401_08870)	rnr	890256..892610 (+)	2355	WP_024477774.1	ribonuclease R	-
R8623_RS04555 (PC0401_08880)	smpB	892573..893040 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
R8623_RS04560 (PC0401_08890)	tehB	893056..893916 (+)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
R8623_RS04565 (PC0401_08900)	coiA	893989..894942 (+)	954	WP_000495911.1	competence protein CoiA	Machinery gene
R8623_RS04570 (PC0401_08910)	pepF	894961..896763 (+)	1803	WP_024477773.1	oligoendopeptidase F	Regulator
R8623_RS04575 (PC0401_08920)	-	896765..897478 (+)	714	WP_000230399.1	O-methyltransferase	-
R8623_RS04580 (PC0401_08930)	prsA	897545..898486 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
R8623_RS04585 (PC0401_08940)	-	898605..898946 (-)	342	Protein_905	transposase	-
R8623_RS04590	-	899358..899453 (+)	96	Protein_906	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38143.79 Da
• Isoelectric Point: 9.1135

>NTDB_id=98581 R8623_RS04565 WP_000495911.1 893989..894942(+) (coiA) [Streptococcus pneumoniae strain PZ900700406]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKGKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKKQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=98581 R8623_RS04565 WP_000495911.1 893989..894942(+) (coiA) [Streptococcus pneumoniae strain PZ900700406]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCTTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGGAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGCCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAAACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: Q8DQ27

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae Rx1	100	100	1
coiA	Streptococcus pneumoniae D39	100	100	1
coiA	Streptococcus pneumoniae R6	100	100	1
coiA	Streptococcus pneumoniae TIGR4	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435