Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   R8635_RS09925 Genome accession   NZ_AP026924
Coordinates   1918140..1918964 (-) Length   274 a.a.
NCBI ID   WP_023396715.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700063     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1913140..1923964
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8635_RS09920 (PC0062_19510) - 1916518..1917849 (-) 1332 WP_000390042.1 hemolysin family protein -
  R8635_RS09925 (PC0062_19520) endA 1918140..1918964 (-) 825 WP_023396715.1 DNA-entry nuclease EndA Machinery gene
  R8635_RS09930 (PC0062_19530) - 1919003..1919191 (-) 189 WP_001036519.1 DNA-directed RNA polymerase subunit beta -
  R8635_RS09935 (PC0062_19540) murA 1919184..1920467 (-) 1284 WP_000358028.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  R8635_RS09940 (PC0062_19550) - 1920491..1920721 (-) 231 WP_000250391.1 DUF1146 family protein -
  R8635_RS09945 (PC0062_19560) sepM 1920779..1921816 (-) 1038 WP_000727277.1 SepM family pheromone-processing serine protease Regulator
  R8635_RS09950 (PC0062_19570) coaD 1921800..1922288 (-) 489 WP_001280746.1 pantetheine-phosphate adenylyltransferase -
  R8635_RS09955 (PC0062_19580) rsmD 1922278..1922817 (-) 540 WP_000691938.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  R8635_RS09960 (PC0062_19590) asnA 1922882..1923874 (-) 993 WP_000747993.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29935.62 Da        Isoelectric Point: 10.1197

>NTDB_id=98294 R8635_RS09925 WP_023396715.1 1918140..1918964(-) (endA) [Streptococcus pneumoniae strain PZ900700063]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLSQKKQAPEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSNATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=98294 R8635_RS09925 WP_023396715.1 1918140..1918964(-) (endA) [Streptococcus pneumoniae strain PZ900700063]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGACAGCTAATAGTCCTAAAACCAAGCTTAGTCAGAAAAAACAAGCGCCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAATGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

97.81

100

0.978
  endA Streptococcus pneumoniae D39

97.81

100

0.978
  endA Streptococcus pneumoniae R6

97.81

100

0.978
  endA Streptococcus pneumoniae TIGR4

97.81

100

0.978

Multiple sequence alignment