Detailed information NTG0978860

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: ACM599_RS05920
• Genome accession: NZ_CP181152
• Coordinates: 1235778..1236551 (+)
• Length: 257 a.a.
• NCBI ID: WP_000055337.1
• Uniprot ID: P63843
• Organism: Staphylococcus aureus strain AG21-0597
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1230778..1241551

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM599_RS05900 (ACM599_05900)	trmFO	1231121..1232428 (+)	1308	WP_000195263.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
ACM599_RS05905 (ACM599_05905)	xerC	1232846..1233742 (+)	897	WP_001015609.1	tyrosine recombinase XerC	-
ACM599_RS05910 (ACM599_05910)	hslV	1233739..1234284 (+)	546	WP_000072681.1	ATP-dependent protease subunit HslV	-
ACM599_RS05915 (ACM599_05915)	hslU	1234350..1235753 (+)	1404	WP_000379051.1	ATP-dependent protease ATPase subunit HslU	-
ACM599_RS05920 (ACM599_05920)	codY	1235778..1236551 (+)	774	WP_000055337.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
ACM599_RS05925 (ACM599_05925)	-	1236602..1236694 (+)	93	WP_031788481.1	hypothetical protein	-
ACM599_RS05930 (ACM599_05930)	rpsB	1236893..1237660 (+)	768	WP_000268484.1	30S ribosomal protein S2	-
ACM599_RS05935 (ACM599_05935)	-	1237694..1237807 (+)	114	WP_001791405.1	hypothetical protein	-
ACM599_RS05940 (ACM599_05940)	tsf	1237842..1238723 (+)	882	WP_000201387.1	translation elongation factor Ts	-
ACM599_RS05945 (ACM599_05945)	pyrH	1238860..1239582 (+)	723	WP_000057330.1	UMP kinase	-
ACM599_RS05950 (ACM599_05950)	frr	1239601..1240155 (+)	555	WP_001280006.1	ribosome recycling factor	-
ACM599_RS05955 (ACM599_05955)	-	1240528..1241298 (+)	771	WP_000473705.1	isoprenyl transferase	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28755.13 Da
• Isoelectric Point: 6.0680

>NTDB_id=978860 ACM599_RS05920 WP_000055337.1 1235778..1236551(+) (codY) [Staphylococcus aureus strain AG21-0597]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide

• Length: 774 bp

>NTDB_id=978860 ACM599_RS05920 WP_000055337.1 1235778..1236551(+) (codY) [Staphylococcus aureus strain AG21-0597]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTTTTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGCGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACACGATG
ACTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCAAT
TGAACATATCTTTGAAGAACTTGGCGGTACAGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAGTAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (2-178)

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

3D structure

• AlphaFold DB: P63843

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	64.202	100	0.642
codY	Lactococcus lactis subsp. lactis strain DGCC12653	42.802	100	0.428