Detailed information NTG0978773

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: ACM6AP_RS06220
• Genome accession: NZ_CP181151
• Coordinates: 1280550..1281323 (+)
• Length: 257 a.a.
• NCBI ID: WP_000055337.1
• Uniprot ID: P63843
• Organism: Staphylococcus aureus strain AG21-0618
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1275550..1286323

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AP_RS06200 (ACM6AP_06200)	trmFO	1275893..1277200 (+)	1308	WP_000195254.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
ACM6AP_RS06205 (ACM6AP_06205)	xerC	1277618..1278514 (+)	897	WP_001015601.1	tyrosine recombinase XerC	-
ACM6AP_RS06210 (ACM6AP_06210)	hslV	1278511..1279056 (+)	546	WP_000072681.1	ATP-dependent protease subunit HslV	-
ACM6AP_RS06215 (ACM6AP_06215)	hslU	1279122..1280525 (+)	1404	WP_000379054.1	ATP-dependent protease ATPase subunit HslU	-
ACM6AP_RS06220 (ACM6AP_06220)	codY	1280550..1281323 (+)	774	WP_000055337.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
ACM6AP_RS06225 (ACM6AP_06225)	-	1281397..1281471 (+)	75	WP_031761472.1	hypothetical protein	-
ACM6AP_RS06230 (ACM6AP_06230)	rpsB	1281670..1282437 (+)	768	WP_000268486.1	30S ribosomal protein S2	-
ACM6AP_RS06235 (ACM6AP_06235)	-	1282471..1282584 (+)	114	WP_001789890.1	hypothetical protein	-
ACM6AP_RS06240 (ACM6AP_06240)	tsf	1282619..1283500 (+)	882	WP_000201392.1	translation elongation factor Ts	-
ACM6AP_RS06245 (ACM6AP_06245)	pyrH	1283637..1284359 (+)	723	WP_000057330.1	UMP kinase	-
ACM6AP_RS06250 (ACM6AP_06250)	frr	1284378..1284932 (+)	555	WP_001280006.1	ribosome recycling factor	-
ACM6AP_RS06255 (ACM6AP_06255)	-	1285305..1286075 (+)	771	WP_000473699.1	isoprenyl transferase	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28755.13 Da
• Isoelectric Point: 6.0680

>NTDB_id=978773 ACM6AP_RS06220 WP_000055337.1 1280550..1281323(+) (codY) [Staphylococcus aureus strain AG21-0618]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide

• Length: 774 bp

>NTDB_id=978773 ACM6AP_RS06220 WP_000055337.1 1280550..1281323(+) (codY) [Staphylococcus aureus strain AG21-0618]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGGTCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (2-178)

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

3D structure

• AlphaFold DB: P63843

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	64.202	100	0.642
codY	Lactococcus lactis subsp. lactis strain DGCC12653	42.802	100	0.428