Detailed information NTG0978595

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: ACM6AA_RS05940
• Genome accession: NZ_CP181149
• Coordinates: 1227759..1228532 (+)
• Length: 257 a.a.
• NCBI ID: WP_000055337.1
• Uniprot ID: P63843
• Organism: Staphylococcus aureus strain AG21-0598
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1222759..1233532

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AA_RS05920 (ACM6AA_05920)	trmFO	1223103..1224410 (+)	1308	WP_000195259.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
ACM6AA_RS05925 (ACM6AA_05925)	xerC	1224827..1225723 (+)	897	WP_154283919.1	tyrosine recombinase XerC	-
ACM6AA_RS05930 (ACM6AA_05930)	hslV	1225720..1226265 (+)	546	WP_000072681.1	ATP-dependent protease subunit HslV	-
ACM6AA_RS05935 (ACM6AA_05935)	hslU	1226331..1227734 (+)	1404	WP_000379054.1	ATP-dependent protease ATPase subunit HslU	-
ACM6AA_RS05940 (ACM6AA_05940)	codY	1227759..1228532 (+)	774	WP_000055337.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
ACM6AA_RS05945 (ACM6AA_05945)	-	1228583..1228675 (+)	93	WP_001790530.1	hypothetical protein	-
ACM6AA_RS05950 (ACM6AA_05950)	rpsB	1228874..1229641 (+)	768	WP_000268484.1	30S ribosomal protein S2	-
ACM6AA_RS05955 (ACM6AA_05955)	-	1229675..1229788 (+)	114	WP_001789890.1	hypothetical protein	-
ACM6AA_RS05960 (ACM6AA_05960)	tsf	1229823..1230704 (+)	882	WP_154283920.1	translation elongation factor Ts	-
ACM6AA_RS05965 (ACM6AA_05965)	pyrH	1230841..1231563 (+)	723	WP_000057330.1	UMP kinase	-
ACM6AA_RS05970 (ACM6AA_05970)	frr	1231582..1232136 (+)	555	WP_001280006.1	ribosome recycling factor	-
ACM6AA_RS05975 (ACM6AA_05975)	-	1232509..1233279 (+)	771	WP_154283921.1	isoprenyl transferase	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28755.13 Da
• Isoelectric Point: 6.0680

>NTDB_id=978595 ACM6AA_RS05940 WP_000055337.1 1227759..1228532(+) (codY) [Staphylococcus aureus strain AG21-0598]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide

• Length: 774 bp

>NTDB_id=978595 ACM6AA_RS05940 WP_000055337.1 1227759..1228532(+) (codY) [Staphylococcus aureus strain AG21-0598]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGGTCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGGGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACTATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCAAT
TGAACATATCTTTGAAGAACTAGGCGGTACGGAAGGTCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (2-178)

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

3D structure

• AlphaFold DB: P63843

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	64.202	100	0.642
codY	Lactococcus lactis subsp. lactis strain DGCC12653	42.802	100	0.428