Detailed information NTG0978417

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: ACM6AW_RS06010
• Genome accession: NZ_CP181145
• Coordinates: 1235006..1235779 (+)
• Length: 257 a.a.
• NCBI ID: WP_000055337.1
• Uniprot ID: P63843
• Organism: Staphylococcus aureus strain AG21-0629
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1230006..1240779

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AW_RS05990 (ACM6AW_05990)	trmFO	1230349..1231656 (+)	1308	WP_000195254.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
ACM6AW_RS05995 (ACM6AW_05995)	xerC	1232074..1232970 (+)	897	WP_031898010.1	tyrosine recombinase XerC	-
ACM6AW_RS06000 (ACM6AW_06000)	hslV	1232967..1233512 (+)	546	WP_000072681.1	ATP-dependent protease subunit HslV	-
ACM6AW_RS06005 (ACM6AW_06005)	hslU	1233578..1234981 (+)	1404	WP_000379054.1	ATP-dependent protease ATPase subunit HslU	-
ACM6AW_RS06010 (ACM6AW_06010)	codY	1235006..1235779 (+)	774	WP_000055337.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
ACM6AW_RS06015 (ACM6AW_06015)	-	1235853..1235927 (+)	75	WP_031761472.1	hypothetical protein	-
ACM6AW_RS06020 (ACM6AW_06020)	rpsB	1236126..1236893 (+)	768	WP_000268484.1	30S ribosomal protein S2	-
ACM6AW_RS06025 (ACM6AW_06025)	-	1236927..1237040 (+)	114	WP_001789890.1	hypothetical protein	-
ACM6AW_RS06030 (ACM6AW_06030)	tsf	1237075..1237956 (+)	882	WP_000201392.1	translation elongation factor Ts	-
ACM6AW_RS06035 (ACM6AW_06035)	pyrH	1238093..1238815 (+)	723	WP_000057330.1	UMP kinase	-
ACM6AW_RS06040 (ACM6AW_06040)	frr	1238834..1239388 (+)	555	WP_001280006.1	ribosome recycling factor	-
ACM6AW_RS06045 (ACM6AW_06045)	-	1239761..1240531 (+)	771	WP_000473699.1	isoprenyl transferase	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28755.13 Da
• Isoelectric Point: 6.0680

>NTDB_id=978417 ACM6AW_RS06010 WP_000055337.1 1235006..1235779(+) (codY) [Staphylococcus aureus strain AG21-0629]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide

• Length: 774 bp

>NTDB_id=978417 ACM6AW_RS06010 WP_000055337.1 1235006..1235779(+) (codY) [Staphylococcus aureus strain AG21-0629]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGGTCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (2-178)

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

3D structure

• AlphaFold DB: P63843

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	64.202	100	0.642
codY	Lactococcus lactis subsp. lactis strain DGCC12653	42.802	100	0.428