Detailed information NTG0978327

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: ACM6AX_RS06015
• Genome accession: NZ_CP181142
• Coordinates: 1236526..1237299 (+)
• Length: 257 a.a.
• NCBI ID: WP_000055337.1
• Uniprot ID: P63843
• Organism: Staphylococcus aureus strain AG21-0630
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1231526..1242299

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AX_RS05995 (ACM6AX_05995)	trmFO	1231869..1233176 (+)	1308	WP_000195254.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
ACM6AX_RS06000 (ACM6AX_06000)	xerC	1233594..1234490 (+)	897	WP_031898010.1	tyrosine recombinase XerC	-
ACM6AX_RS06005 (ACM6AX_06005)	hslV	1234487..1235032 (+)	546	WP_000072681.1	ATP-dependent protease subunit HslV	-
ACM6AX_RS06010 (ACM6AX_06010)	hslU	1235098..1236501 (+)	1404	WP_000379054.1	ATP-dependent protease ATPase subunit HslU	-
ACM6AX_RS06015 (ACM6AX_06015)	codY	1236526..1237299 (+)	774	WP_000055337.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
ACM6AX_RS06020 (ACM6AX_06020)	-	1237373..1237447 (+)	75	WP_031761472.1	hypothetical protein	-
ACM6AX_RS06025 (ACM6AX_06025)	rpsB	1237646..1238413 (+)	768	WP_000268484.1	30S ribosomal protein S2	-
ACM6AX_RS06030 (ACM6AX_06030)	-	1238447..1238560 (+)	114	WP_001789890.1	hypothetical protein	-
ACM6AX_RS06035 (ACM6AX_06035)	tsf	1238595..1239476 (+)	882	WP_000201392.1	translation elongation factor Ts	-
ACM6AX_RS06040 (ACM6AX_06040)	pyrH	1239613..1240335 (+)	723	WP_000057330.1	UMP kinase	-
ACM6AX_RS06045 (ACM6AX_06045)	frr	1240354..1240908 (+)	555	WP_001280006.1	ribosome recycling factor	-
ACM6AX_RS06050 (ACM6AX_06050)	-	1241281..1242051 (+)	771	WP_000473699.1	isoprenyl transferase	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28755.13 Da
• Isoelectric Point: 6.0680

>NTDB_id=978327 ACM6AX_RS06015 WP_000055337.1 1236526..1237299(+) (codY) [Staphylococcus aureus strain AG21-0630]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide

• Length: 774 bp

>NTDB_id=978327 ACM6AX_RS06015 WP_000055337.1 1236526..1237299(+) (codY) [Staphylococcus aureus strain AG21-0630]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGGTCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (2-178)

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

3D structure

• AlphaFold DB: P63843

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	64.202	100	0.642
codY	Lactococcus lactis subsp. lactis strain DGCC12653	42.802	100	0.428