Detailed information NTG0978240

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: ACM6AB_RS06460
• Genome accession: NZ_CP181140
• Coordinates: 1301249..1302022 (+)
• Length: 257 a.a.
• NCBI ID: WP_000055337.1
• Uniprot ID: P63843
• Organism: Staphylococcus aureus strain AG21-0599
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1296249..1307022

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AB_RS06440 (ACM6AB_06440)	trmFO	1296592..1297899 (+)	1308	WP_000195254.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
ACM6AB_RS06445 (ACM6AB_06445)	xerC	1298317..1299213 (+)	897	WP_001015601.1	tyrosine recombinase XerC	-
ACM6AB_RS06450 (ACM6AB_06450)	hslV	1299210..1299755 (+)	546	WP_000072681.1	ATP-dependent protease subunit HslV	-
ACM6AB_RS06455 (ACM6AB_06455)	hslU	1299821..1301224 (+)	1404	WP_000379054.1	ATP-dependent protease ATPase subunit HslU	-
ACM6AB_RS06460 (ACM6AB_06460)	codY	1301249..1302022 (+)	774	WP_000055337.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
ACM6AB_RS06465 (ACM6AB_06465)	-	1302096..1302170 (+)	75	WP_031761472.1	hypothetical protein	-
ACM6AB_RS06470 (ACM6AB_06470)	rpsB	1302369..1303136 (+)	768	WP_000268486.1	30S ribosomal protein S2	-
ACM6AB_RS06475 (ACM6AB_06475)	-	1303170..1303283 (+)	114	WP_001789890.1	hypothetical protein	-
ACM6AB_RS06480 (ACM6AB_06480)	tsf	1303318..1304199 (+)	882	WP_000201392.1	translation elongation factor Ts	-
ACM6AB_RS06485 (ACM6AB_06485)	pyrH	1304336..1305058 (+)	723	WP_000057330.1	UMP kinase	-
ACM6AB_RS06490 (ACM6AB_06490)	frr	1305077..1305631 (+)	555	WP_001280006.1	ribosome recycling factor	-
ACM6AB_RS06495 (ACM6AB_06495)	-	1306004..1306774 (+)	771	WP_000473699.1	isoprenyl transferase	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28755.13 Da
• Isoelectric Point: 6.0680

>NTDB_id=978240 ACM6AB_RS06460 WP_000055337.1 1301249..1302022(+) (codY) [Staphylococcus aureus strain AG21-0599]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide

• Length: 774 bp

>NTDB_id=978240 ACM6AB_RS06460 WP_000055337.1 1301249..1302022(+) (codY) [Staphylococcus aureus strain AG21-0599]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGGTCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (2-178)

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

3D structure

• AlphaFold DB: P63843

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	64.202	100	0.642
codY	Lactococcus lactis subsp. lactis strain DGCC12653	42.802	100	0.428