Detailed information NTG0978152

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: ACM6AD_RS06250
• Genome accession: NZ_CP181138
• Coordinates: 1274802..1275575 (+)
• Length: 257 a.a.
• NCBI ID: WP_000055337.1
• Uniprot ID: P63843
• Organism: Staphylococcus aureus strain AG21-0601
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1269802..1280575

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AD_RS06230 (ACM6AD_06230)	trmFO	1270145..1271452 (+)	1308	WP_000195254.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
ACM6AD_RS06235 (ACM6AD_06235)	xerC	1271870..1272766 (+)	897	WP_001015601.1	tyrosine recombinase XerC	-
ACM6AD_RS06240 (ACM6AD_06240)	hslV	1272763..1273308 (+)	546	WP_000072681.1	ATP-dependent protease subunit HslV	-
ACM6AD_RS06245 (ACM6AD_06245)	hslU	1273374..1274777 (+)	1404	WP_000379054.1	ATP-dependent protease ATPase subunit HslU	-
ACM6AD_RS06250 (ACM6AD_06250)	codY	1274802..1275575 (+)	774	WP_000055337.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
ACM6AD_RS06255 (ACM6AD_06255)	-	1275649..1275723 (+)	75	WP_031761472.1	hypothetical protein	-
ACM6AD_RS06260 (ACM6AD_06260)	rpsB	1275922..1276689 (+)	768	WP_000268486.1	30S ribosomal protein S2	-
ACM6AD_RS06265 (ACM6AD_06265)	-	1276723..1276836 (+)	114	WP_001789890.1	hypothetical protein	-
ACM6AD_RS06270 (ACM6AD_06270)	tsf	1276871..1277752 (+)	882	WP_000201392.1	translation elongation factor Ts	-
ACM6AD_RS06275 (ACM6AD_06275)	pyrH	1277889..1278611 (+)	723	WP_000057330.1	UMP kinase	-
ACM6AD_RS06280 (ACM6AD_06280)	frr	1278630..1279184 (+)	555	WP_001280006.1	ribosome recycling factor	-
ACM6AD_RS06285 (ACM6AD_06285)	-	1279557..1280327 (+)	771	WP_000473699.1	isoprenyl transferase	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28755.13 Da
• Isoelectric Point: 6.0680

>NTDB_id=978152 ACM6AD_RS06250 WP_000055337.1 1274802..1275575(+) (codY) [Staphylococcus aureus strain AG21-0601]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide

• Length: 774 bp

>NTDB_id=978152 ACM6AD_RS06250 WP_000055337.1 1274802..1275575(+) (codY) [Staphylococcus aureus strain AG21-0601]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGGTCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (2-178)

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

3D structure

• AlphaFold DB: P63843

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	64.202	100	0.642
codY	Lactococcus lactis subsp. lactis strain DGCC12653	42.802	100	0.428