Detailed information NTG0978064

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: ACM6AQ_RS05820
• Genome accession: NZ_CP181136
• Coordinates: 1194750..1195523 (+)
• Length: 257 a.a.
• NCBI ID: WP_000055337.1
• Uniprot ID: P63843
• Organism: Staphylococcus aureus strain AG21-0619
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1189750..1200523

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AQ_RS05800 (ACM6AQ_05800)	trmFO	1190094..1191401 (+)	1308	WP_072491544.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
ACM6AQ_RS05805 (ACM6AQ_05805)	xerC	1191818..1192714 (+)	897	WP_001015609.1	tyrosine recombinase XerC	-
ACM6AQ_RS05810 (ACM6AQ_05810)	hslV	1192711..1193256 (+)	546	WP_000072681.1	ATP-dependent protease subunit HslV	-
ACM6AQ_RS05815 (ACM6AQ_05815)	hslU	1193322..1194725 (+)	1404	WP_098817802.1	ATP-dependent protease ATPase subunit HslU	-
ACM6AQ_RS05820 (ACM6AQ_05820)	codY	1194750..1195523 (+)	774	WP_000055337.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
ACM6AQ_RS05825 (ACM6AQ_05825)	-	1195574..1195666 (+)	93	WP_031788481.1	hypothetical protein	-
ACM6AQ_RS05830 (ACM6AQ_05830)	rpsB	1195865..1196632 (+)	768	WP_031786209.1	30S ribosomal protein S2	-
ACM6AQ_RS05835 (ACM6AQ_05835)	-	1196666..1196779 (+)	114	WP_001789890.1	hypothetical protein	-
ACM6AQ_RS05840 (ACM6AQ_05840)	tsf	1196814..1197695 (+)	882	WP_000201387.1	translation elongation factor Ts	-
ACM6AQ_RS05845 (ACM6AQ_05845)	pyrH	1197832..1198554 (+)	723	WP_000057330.1	UMP kinase	-
ACM6AQ_RS05850 (ACM6AQ_05850)	frr	1198573..1199127 (+)	555	WP_001280006.1	ribosome recycling factor	-
ACM6AQ_RS05855 (ACM6AQ_05855)	-	1199500..1200270 (+)	771	WP_000473705.1	isoprenyl transferase	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28755.13 Da
• Isoelectric Point: 6.0680

>NTDB_id=978064 ACM6AQ_RS05820 WP_000055337.1 1194750..1195523(+) (codY) [Staphylococcus aureus strain AG21-0619]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide

• Length: 774 bp

>NTDB_id=978064 ACM6AQ_RS05820 WP_000055337.1 1194750..1195523(+) (codY) [Staphylococcus aureus strain AG21-0619]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTTTTCCCGCCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCAAT
TGAACATATCTTTGAAGAACTTGGTGGTACGGAAGGTCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAGTCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAGTAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (2-178)

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

3D structure

• AlphaFold DB: P63843

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	64.202	100	0.642
codY	Lactococcus lactis subsp. lactis strain DGCC12653	42.802	100	0.428