Detailed information NTG0977976

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: ACM6EM_RS06265
• Genome accession: NZ_CP181134
• Coordinates: 1279892..1280665 (+)
• Length: 257 a.a.
• NCBI ID: WP_000055337.1
• Uniprot ID: P63843
• Organism: Staphylococcus aureus strain AG21-0594
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1274892..1285665

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6EM_RS06245 (ACM6EM_06245)	trmFO	1275236..1276543 (+)	1308	WP_000195254.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
ACM6EM_RS06250 (ACM6EM_06250)	xerC	1276960..1277856 (+)	897	WP_001015597.1	tyrosine recombinase XerC	-
ACM6EM_RS06255 (ACM6EM_06255)	hslV	1277853..1278398 (+)	546	WP_000072681.1	ATP-dependent protease subunit HslV	-
ACM6EM_RS06260 (ACM6EM_06260)	hslU	1278464..1279867 (+)	1404	WP_416152307.1	ATP-dependent protease ATPase subunit HslU	-
ACM6EM_RS06265 (ACM6EM_06265)	codY	1279892..1280665 (+)	774	WP_000055337.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
ACM6EM_RS06270 (ACM6EM_06270)	-	1280716..1280808 (+)	93	WP_001790530.1	hypothetical protein	-
ACM6EM_RS06275 (ACM6EM_06275)	rpsB	1281007..1281774 (+)	768	WP_000268484.1	30S ribosomal protein S2	-
ACM6EM_RS06280 (ACM6EM_06280)	-	1281808..1281921 (+)	114	WP_001789890.1	hypothetical protein	-
ACM6EM_RS06285 (ACM6EM_06285)	tsf	1281956..1282837 (+)	882	WP_000201387.1	translation elongation factor Ts	-
ACM6EM_RS06290 (ACM6EM_06290)	pyrH	1282974..1283696 (+)	723	WP_000057330.1	UMP kinase	-
ACM6EM_RS06295 (ACM6EM_06295)	frr	1283715..1284269 (+)	555	WP_001280006.1	ribosome recycling factor	-
ACM6EM_RS06300 (ACM6EM_06300)	-	1284642..1285412 (+)	771	WP_000473705.1	isoprenyl transferase	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28755.13 Da
• Isoelectric Point: 6.0680

>NTDB_id=977976 ACM6EM_RS06265 WP_000055337.1 1279892..1280665(+) (codY) [Staphylococcus aureus strain AG21-0594]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide

• Length: 774 bp

>NTDB_id=977976 ACM6EM_RS06265 WP_000055337.1 1279892..1280665(+) (codY) [Staphylococcus aureus strain AG21-0594]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGGGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (2-178)

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

3D structure

• AlphaFold DB: P63843

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	64.202	100	0.642
codY	Lactococcus lactis subsp. lactis strain DGCC12653	42.802	100	0.428