Detailed information NTG0977004

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: ACM6AL_RS06260
• Genome accession: NZ_CP181107
• Coordinates: 1278626..1279399 (+)
• Length: 257 a.a.
• NCBI ID: WP_000055337.1
• Uniprot ID: P63843
• Organism: Staphylococcus aureus strain AG21-0612
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1273626..1284399

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AL_RS06240 (ACM6AL_06240)	trmFO	1273970..1275277 (+)	1308	WP_000195254.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
ACM6AL_RS06245 (ACM6AL_06245)	xerC	1275694..1276590 (+)	897	WP_001015597.1	tyrosine recombinase XerC	-
ACM6AL_RS06250 (ACM6AL_06250)	hslV	1276587..1277132 (+)	546	WP_000072681.1	ATP-dependent protease subunit HslV	-
ACM6AL_RS06255 (ACM6AL_06255)	hslU	1277198..1278601 (+)	1404	WP_000379054.1	ATP-dependent protease ATPase subunit HslU	-
ACM6AL_RS06260 (ACM6AL_06260)	codY	1278626..1279399 (+)	774	WP_000055337.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
ACM6AL_RS06265 (ACM6AL_06265)	-	1279450..1279542 (+)	93	WP_001790530.1	hypothetical protein	-
ACM6AL_RS06270 (ACM6AL_06270)	rpsB	1279741..1280508 (+)	768	WP_000268484.1	30S ribosomal protein S2	-
ACM6AL_RS06275 (ACM6AL_06275)	-	1280542..1280655 (+)	114	WP_001789890.1	hypothetical protein	-
ACM6AL_RS06280 (ACM6AL_06280)	tsf	1280690..1281571 (+)	882	WP_000201387.1	translation elongation factor Ts	-
ACM6AL_RS06285 (ACM6AL_06285)	pyrH	1281708..1282430 (+)	723	WP_000057330.1	UMP kinase	-
ACM6AL_RS06290 (ACM6AL_06290)	frr	1282449..1283003 (+)	555	WP_001280006.1	ribosome recycling factor	-
ACM6AL_RS06295 (ACM6AL_06295)	-	1283376..1284146 (+)	771	WP_000473705.1	isoprenyl transferase	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28755.13 Da
• Isoelectric Point: 6.0680

>NTDB_id=977004 ACM6AL_RS06260 WP_000055337.1 1278626..1279399(+) (codY) [Staphylococcus aureus strain AG21-0612]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide

• Length: 774 bp

>NTDB_id=977004 ACM6AL_RS06260 WP_000055337.1 1278626..1279399(+) (codY) [Staphylococcus aureus strain AG21-0612]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGGGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (2-178)

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

3D structure

• AlphaFold DB: P63843

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	64.202	100	0.642
codY	Lactococcus lactis subsp. lactis strain DGCC12653	42.802	100	0.428