Detailed information NTG0976941

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: MGAS38289_RS07405
• Genome accession: NZ_CP151440
• Coordinates: 1446113..1446838 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain MGAS38289
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1441113..1451838

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS38289_RS07370 (MGAS38289_03020)	-	1441247..1441630 (+)	384	WP_002988673.1	ImmA/IrrE family metallo-endopeptidase	-
MGAS38289_RS07375 (MGAS38289_03022)	-	1441641..1442192 (+)	552	WP_002988670.1	hypothetical protein	-
MGAS38289_RS07380 (MGAS38289_03024)	-	1442309..1443388 (+)	1080	WP_002988667.1	site-specific integrase	-
MGAS38289_RS07390 (MGAS38289_03028)	trmB	1443586..1444221 (-)	636	WP_002983387.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
MGAS38289_RS07395 (MGAS38289_03030)	ccrZ	1444221..1445012 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
MGAS38289_RS07400 (MGAS38289_03032)	-	1445076..1446110 (-)	1035	WP_010922583.1	ABC transporter permease	-
MGAS38289_RS07405 (MGAS38289_03034)	pptA	1446113..1446838 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
MGAS38289_RS07410 (MGAS38289_03036)	-	1446910..1447329 (+)	420	WP_002983376.1	HIT family protein	-
MGAS38289_RS07415 (MGAS38289_03038)	-	1447326..1447682 (+)	357	WP_002988657.1	hypothetical protein	-
MGAS38289_RS07420 (MGAS38289_03040)	brpA	1447793..1449067 (-)	1275	WP_010922584.1	biofilm formation/cell division transcriptional regulator BrpA	-
MGAS38289_RS07425 (MGAS38289_03042)	-	1449076..1449600 (-)	525	WP_009880752.1	GNAT family N-acetyltransferase	-
MGAS38289_RS07430 (MGAS38289_03044)	tsaE	1449575..1450036 (-)	462	WP_009880751.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
MGAS38289_RS07435 (MGAS38289_03046)	-	1450190..1451650 (-)	1461	WP_011285677.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=976941 MGAS38289_RS07405 WP_002983379.1 1446113..1446838(-) (pptA) [Streptococcus pyogenes strain MGAS38289]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=976941 MGAS38289_RS07405 WP_002983379.1 1446113..1446838(-) (pptA) [Streptococcus pyogenes strain MGAS38289]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714