Detailed information NTG0976829

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: ACM6AN_RS06685
• Genome accession: NZ_CP181102
• Coordinates: 1337463..1338236 (+)
• Length: 257 a.a.
• NCBI ID: WP_000055337.1
• Uniprot ID: P63843
• Organism: Staphylococcus aureus strain AG21-0614
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1332463..1343236

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AN_RS06665 (ACM6AN_06665)	trmFO	1332806..1334113 (+)	1308	WP_000195254.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
ACM6AN_RS06670 (ACM6AN_06670)	xerC	1334531..1335427 (+)	897	WP_001015601.1	tyrosine recombinase XerC	-
ACM6AN_RS06675 (ACM6AN_06675)	hslV	1335424..1335969 (+)	546	WP_000072681.1	ATP-dependent protease subunit HslV	-
ACM6AN_RS06680 (ACM6AN_06680)	hslU	1336035..1337438 (+)	1404	WP_000379054.1	ATP-dependent protease ATPase subunit HslU	-
ACM6AN_RS06685 (ACM6AN_06685)	codY	1337463..1338236 (+)	774	WP_000055337.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
ACM6AN_RS06690 (ACM6AN_06690)	-	1338310..1338384 (+)	75	WP_031761472.1	hypothetical protein	-
ACM6AN_RS06695 (ACM6AN_06695)	rpsB	1338583..1339350 (+)	768	WP_000268484.1	30S ribosomal protein S2	-
ACM6AN_RS06700 (ACM6AN_06700)	-	1339384..1339497 (+)	114	WP_001789890.1	hypothetical protein	-
ACM6AN_RS06705 (ACM6AN_06705)	tsf	1339532..1340413 (+)	882	WP_000201392.1	translation elongation factor Ts	-
ACM6AN_RS06710 (ACM6AN_06710)	pyrH	1340550..1341272 (+)	723	WP_000057330.1	UMP kinase	-
ACM6AN_RS06715 (ACM6AN_06715)	frr	1341291..1341845 (+)	555	WP_001280006.1	ribosome recycling factor	-
ACM6AN_RS06720 (ACM6AN_06720)	-	1342218..1342988 (+)	771	WP_000473699.1	isoprenyl transferase	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28755.13 Da
• Isoelectric Point: 6.0680

>NTDB_id=976829 ACM6AN_RS06685 WP_000055337.1 1337463..1338236(+) (codY) [Staphylococcus aureus strain AG21-0614]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide

• Length: 774 bp

>NTDB_id=976829 ACM6AN_RS06685 WP_000055337.1 1337463..1338236(+) (codY) [Staphylococcus aureus strain AG21-0614]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGGTCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (2-178)

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

3D structure

• AlphaFold DB: P63843

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	64.202	100	0.642
codY	Lactococcus lactis subsp. lactis strain DGCC12653	42.802	100	0.428