Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   R8522_RS09030 Genome accession   NZ_AP026916
Coordinates   1766477..1767136 (+) Length   219 a.a.
NCBI ID   WP_000565010.1    Uniprot ID   A0A0B7M2C6
Organism   Streptococcus pneumoniae strain PZ900700006     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1761477..1772136
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8522_RS09005 (PC0006_18340) - 1761782..1762099 (-) 318 WP_001151646.1 PTS sugar transporter subunit IIB -
  R8522_RS09010 (PC0006_18350) - 1762114..1763010 (-) 897 WP_000825669.1 PEP phosphonomutase -
  R8522_RS09015 (PC0006_18360) - 1763013..1764275 (-) 1263 WP_000413336.1 PTS sugar transporter subunit IIC -
  R8522_RS09020 (PC0006_18370) - 1764555..1765733 (+) 1179 WP_000175876.1 ROK family transcriptional regulator -
  R8522_RS09025 (PC0006_18380) - 1766009..1766407 (-) 399 WP_000155403.1 N-acetyltransferase -
  R8522_RS09030 (PC0006_18390) cclA/cilC 1766477..1767136 (+) 660 WP_000565010.1 A24 family peptidase Machinery gene
  R8522_RS09035 (PC0006_18400) - 1767188..1768339 (-) 1152 WP_000481750.1 ImmA/IrrE family metallo-endopeptidase -
  R8522_RS09040 (PC0006_18410) - 1768354..1769085 (-) 732 Protein_1793 hypothetical protein -
  R8522_RS09045 - 1769305..1769415 (+) 111 Protein_1794 prepilin peptidase -
  R8522_RS09050 (PC0006_18430) trpA 1769387..1770163 (-) 777 WP_054367390.1 tryptophan synthase subunit alpha -
  R8522_RS09055 (PC0006_18440) trpB 1770156..1771379 (-) 1224 WP_000331298.1 tryptophan synthase subunit beta -
  R8522_RS09060 (PC0006_18450) - 1771357..1771956 (-) 600 WP_000169893.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24845.99 Da        Isoelectric Point: 7.5762

>NTDB_id=97653 R8522_RS09030 WP_000565010.1 1766477..1767136(+) (cclA/cilC) [Streptococcus pneumoniae strain PZ900700006]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLSQVILITAGLTLGIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=97653 R8522_RS09030 WP_000565010.1 1766477..1767136(+) (cclA/cilC) [Streptococcus pneumoniae strain PZ900700006]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTTGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTACTTTCCTTGAGTCAAGTCATCCTAATCACTGCTGGTTTGACCTTGGGCAT
CTACGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTT
TTTTTAGCTTCTTGCGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTGCTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M2C6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae Rx1

100

100

1
  cclA/cilC Streptococcus pneumoniae D39

100

100

1
  cclA/cilC Streptococcus pneumoniae R6

100

100

1
  cclA/cilC Streptococcus pneumoniae TIGR4

94.977

100

0.95
  cclA/cilC Streptococcus mitis SK321

92.694

100

0.927
  cclA/cilC Streptococcus mitis NCTC 12261

87.671

100

0.877

Multiple sequence alignment